Art. -Nr.: HY-10007

NPS-2143

(Synonyms: SB-262470A)

30 Cited Publications

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Based on 30 publication(s) in Google Scholar

NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca²⁺ concentrations (IC₅₀=43 nM) elicited by activating the Ca²⁺ receptor in HEK 293 cells expressing the human Ca²⁺ receptor.

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Reinheit: 99.94%
CAS. Nr.: 284035-33-2
Formel: C₂₄H₂₅ClN₂O₂
Molecular Weight:408.92

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year

NPS-2143 Chemical Structure

CAS. Nr.: 284035-33-2

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
- In Vivo
Chemical Information
Publications (30)
Lösungsmittel & Löslichkeit
- In Vitro
- In Vivo
Protokoll
Reinheit & Dokumentation
Verweise
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

IC50: 43 nM (Ca²⁺ receptor)

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	0.46 μM Compound: 3, NPS 2143	Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulation	[PMID: 16913701]
HEK293	IC₅₀	0.003 nM Compound: 3	Displacement of [3H](2-(2-hydroxyphenyl)-6-methyl-5-(2-methylpropyl)-3-(2-phenylethyl)-4(3H)-pyrimidinone) from human calcium receptor expressed in human HEK293 4.0-7 cells by liquid scintillation counting Displacement of [3H](2-(2-hydroxyphenyl)-6-methyl-5-(2-methylpropyl)-3-(2-phenylethyl)-4(3H)-pyrimidinone) from human calcium receptor expressed in human HEK293 4.0-7 cells by liquid scintillation counting	[PMID: 19821575]
HEK293	IC₅₀	0.043 μM Compound: NPS-2143	Inhibitory concentration against human calcium receptor expressed in HEK 293 cells Inhibitory concentration against human calcium receptor expressed in HEK 293 cells	[PMID: 15745796]
HEK293	IC₅₀	0.058 nM Compound: 3	Antagonist activity at human calcium receptor expressed in HEK293 4.0-7 cells assessed as inhibition of intracellular calcium release by FLIPR assay Antagonist activity at human calcium receptor expressed in HEK293 4.0-7 cells assessed as inhibition of intracellular calcium release by FLIPR assay	[PMID: 19821575]
HEK293	IC₅₀	0.08 μM Compound: NPS-2143	Inhibitory concentration for the inhibition of intracellular [Ca2+] release in HEK cells by using FLIPR technology Inhibitory concentration for the inhibition of intracellular [Ca2+] release in HEK cells by using FLIPR technology	[PMID: 15686947]
HEK293	IC₅₀	23 nM Compound: NPS-2143	Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cells Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cells	[PMID: 19442519]
HEK293	IC₅₀	43 nM Compound: 27, NPS2143	Inhibition of human CaSR expressed in HEK293 cells Inhibition of human CaSR expressed in HEK293 cells	[PMID: 20218623]
PC-12	IC₅₀	0.026 μM Compound: NPS-2143	Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assay Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assay	[PMID: 20472433]
TT	IC₅₀	0.05 μM Compound: 1, NPS-2143	Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPR	[PMID: 16216508]

In Vitro

NPS-2143 (SB-262470A) stimulates parathyroid hormone (PTH) secretion from bovine parathyroid cells with EC₅₀ of 41 nM. Moreover, NPS 214 also blocks the inhibitory effects of calcimimetic NPS R-467 on PTH secretion from bovine parathyroid cells and the inhibitory effects of extracellular Ca²⁺ on isoproterenol-stimulated increases in cyclic AMP formation^[1].
In HEK 293 cells transiently expressing hCaSRs, NPS-2143 significantly suppresses the kokumi taste by effectively inhibiting the activity of both GSH and γ-Glu-Val-Gly^[3]. NPS-2143 treatment suppresses low molecular weight fractions of azuki hydrolysate-induced cholecystokinin (CCK) secretion in CaSR-transfected HEK 293 cells^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

NPS-2143 (SB-262470A) results in a rapid 4- to 5-fold increase in plasma PTH levels in rats^[1].
In normotensive rats, NPS-2143 administration (1 mg/kg, i.v.) markedly increases mean arterial blood pressure (MAP) in the presence of parathyroid glands^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 284035-33-2
Appearance Solid
Molecular Weight 408.92
Formel C₂₄H₂₅ClN₂O₂
Color White to off-white
SMILES

N#CC1=C(OC[C@@H](CNC(C)(CC2=CC=C3C=CC=CC3=C2)C)O)C=CC=C1Cl
Synonyms

SB-262470A
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Publications (30)

All WB

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Journal Impact Factor

Int J Biol Sci

The Interaction of Calcium-Sensing Receptor with KIF11 Enhances Cisplatin Resistance in Lung Adenocarcinoma via BRCA1/cyclin B1 pathway. [Abstract]

2024 Jul 15;20(10):3892-3910. PMID: 39113697
Food Chem

Targeted discovery of pea protein-derived GLP-1-secreting peptides by CaSR activation-based molecular docking and their digestive stability. [Abstract]

2024 Oct 10;464(Pt 1):141569. PMID: 39418954
Phytomedicine

Matrine, as a CaSR agonist promotes intestinal GLP-1 secretion and improves insulin resistance in diabetes mellitus. [Abstract]

2021 Apr:84:153507. PMID: 33636577
J Agric Food Chem

Novel Cholecystokinin Secretion-Stimulating Peptides from Oat Protein Hydrolysate: Sequence Identification and Insight into the Mechanism of Action. [Abstract]

2025 Apr 25. PMID: 40275796
Int J Mol Med

Astragaloside IV attenuates cerebral ischemia‑reperfusion injury in rats through the inhibition of calcium‑sensing receptor‑mediated apoptosis. [Abstract]

2021 Jan;47(1):302-314. PMID: 33416112
Acta Physiol

Upregulated Calcium Sensing Receptor Mediates Pulmonary Venous Remodeling in Pulmonary Hypertension. [Abstract]

2026 Jan;242(1):e70142. PMID: 41387174
Acta Physiol

The CaSR/TRPV4 coupling mediates pro-inflammatory macrophage function. [Abstract]

2023 Apr;237(4):e13926. PMID: 36606511
Food Funct

Bioactive peptides from barley protein hydrolysate stimulate cholecystokinin secretion via calcium-sensing receptor signaling in enteroendocrine cells. [Abstract]

2025 Mar 26. PMID: 40134323
Food Funct

Digestion characteristics of quinoa, barley and mungbean proteins and the effects of their simulated gastrointestinal digests on CCK secretion in enteroendocrine STC-1 cells. [Abstract]

2022 Jun 6;13(11):6233-6243. PMID: 35587126
J Clin Endocrinol Metab

Heterogenous Origins of Calcium Homeostasis Disorders Arising from Five Heterozygous Calcium-Sensing Receptor Variants. [Abstract]

2024 Oct 16:dgae735. PMID: 39413244
Int J Mol Sci

The CaSR Modulator NPS-2143 Reduced UV-Induced DNA Damage in Skh:hr1 Hairless Mice but Minimally Inhibited Skin Tumours. [Abstract]

2023 Mar 3;24(5):4921. PMID: 36902353
Front Pharmacol

Ca2+-Permeable Channels/Ca2+ Signaling in the Regulation of Ileal Na+/Gln Co-Transport in Mice. [Abstract]

2022 Feb 23;13:816133. PMID: 35281933
Bioorg Chem

L-tetrahydropalmatine attenuates methamphetamine-induced pulmonary vascular remodeling via CaSR-BMP2/mTOR signaling. [Abstract]

2025 Dec 21:169:109418. PMID: 41443015
Am J Physiol Heart Circ Physiol

Calcium-sensing receptor: a sensor and mediator of ischemic preconditioning in the heart. [Abstract]

2010 Nov;299(5):H1309-17. PMID: 20833954

NPS-2143 purchased from MedChemExpress. Usage Cited in: Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1309-17. [Abstract]

Distribution of cardioprotective signaling kinases among fractions prepared from perfusion, IPC, and NPS2143-treated IPC hearts. After nondetergent caveolae fractionation via sucrose gradient ultracentrifugation, equal volume of each collected sucrose fraction is subjected to 4–12% SDS-PAGE under reducing condition and followed with p-ERK1/2 (A), p-AKT (B), and p-GSK-3β (C) IB detection. The representative IBs are taken and shown from one out of three independent experiments.
Sci Rep

NPS-2143 suppresses malignant phenotypes of retinoblastoma cells involved in regulating NF-κB pathway. [Abstract]

2025 May 9;15(1):16209. PMID: 40346093
Sci Rep

Shape-dependent toxicity and mineralization of hydroxyapatite nanoparticles in A7R5 aortic smooth muscle cells. [Abstract]

2019 Dec 12;9(1):18979. PMID: 31831831
J Food Sci

Sensing of L-Arginine by Gut-Expressed Calcium Sensing Receptor Stimulates Gut Satiety Hormones Cholecystokinin and Glucose-Dependent Insulinotropic Peptide Secretion in Pig Model. [Abstract]

2018 Sep;83(9):2394-2401. PMID: 30088839
J Tradit Complement Med

Xinbao pill attenuated water retention by regulating the CaSR/AQP2 pathway in LAD-induced chronic heart failure rats. [Abstract]

2024 Jul 2;15(5):495-508. PMID: 40979484
Photochem Photobiol

UV-induced DNA Damage in Skin is Reduced by CaSR Inhibition. [Abstract]

2022 Sep;98(5):1157-1166. PMID: 35288938
PeerJ

Cholesterol and steroid synthesis pathways may be involved in the inhibition of osteosarcoma cell viability by calcium-sensing receptor antagonism. [Abstract]

2026 Jan 5:14:e20546. PMID: 41522513
Toxicon

Deoxynivalenol-induced anorexia is mediated by brain-gut peptides through CaSR-TRPM5 signaling axis. [Abstract]

2026 Jan:269:108660. PMID: 41241198
FEBS Open Bio

Calcium-sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter. [Abstract]

2025 Oct 13. PMID: 41081312
FASEB Bioadv

Levo-Tryptophan Promotes Osteogenesis Through Calcium-Sensing Receptor. [Abstract]

2025 Sep 3;7(8):e70045. PMID: 40909871
Neurosci Lett

Inhibition of calcium-sensing receptor by its antagonist protects dopaminergic neurons from MPTP/MPP+-induced neurotoxicity via regulating mitochondrial function, autophagy, and apoptosis in vivo and in vitro. [Abstract]

2025 Aug 9:865:138351. PMID: 40789434
Gen Comp Endocrinol

Phenylalanine and tryptophan stimulate gastrin and somatostatin secretion and H+-K+-ATPase activity in pigs through calcium-sensing receptor. [Abstract]

2018 Oct 1:267:1-8. PMID: 29782837
J Vet Sci

Calcium-sensing receptor-mediated L-tryptophan-induced secretion of cholecystokinin and glucose-dependent insulinotropic peptide in swine duodenum. [Abstract]

2018 Mar 31;19(2):179-187. PMID: 29284209

NPS-2143 purchased from MedChemExpress. Usage Cited in: J Vet Sci. 2018 Mar 31;19(2):179-187. [Abstract]

The protein levels of calcium-sensing receptor (CaSR) and its signal molecules regulated by CaSR antagonist NPS 2143. The protein images of CaSR, protein kinase C (PKC), and inositol trisphosphate receptor (IP3R) in the presence of 20 mM tryptophan and NPS 2143.
University of Verona

2025.
University of Verona

2025.
Oxid Med Cell Longev

Exosomes Released from CaSR-Stimulated PMNs Reduce Ischaemia/Reperfusion Injury. [Abstract]

2021 Jan 12;2021:3010548. PMID: 33505580
Oxid Med Cell Longev

Expression and Role of the Calcium-Sensing Receptor in Rat Peripheral Blood Polymorphonuclear Neutrophils. [Abstract]

2017:2017:3869561. PMID: 29081886

NPS-2143 purchased from MedChemExpress. Usage Cited in: Oxid Med Cell Longev. 2017:2017:3869561. [Abstract]

N-formyl-Met-Leu-Phe (fMLP; 10 nM) are used to stimulate the cells for 2 min, and the polymorphonuclear neutrophils (PMNs) without fMLP serve as the control. NPS-2143 (100 nM), Cinacalcet (100 nM), and PDTC (100 nM) are added and incubated. Protein expression results are representative of three experiments.

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (244.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4455 mL

12.2273 mL

24.4546 mL

5 mM

0.4891 mL

2.4455 mL

4.8909 mL

10 mM

0.2445 mL

1.2227 mL

2.4455 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline

Solubility: ≥ 2.5 mg/mL (6.11 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil

Solubility: ≥ 2.5 mg/mL (6.11 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Protokoll

Kinase Assay^[1]

This clonal cell line, referred to as HEK 293 4.0-7 cells, are used in a high-throughput screening format to detect agonists and allosteric activators of the Ca²⁺ receptor. Changes in the concentration of cytoplasmic [Ca²⁺]i provide a quantitative and functional assessment of Ca²⁺ receptor activity in these cells and the results using this assay parallel those obtained using a homologous expression system of bovine parathyroid cells. On-line continuous measurements of fluorescence in fluo-3- or fura-2-loaded HEK 293 4.0-7 cells are obtained using a custom-built spectrofluorimeter or a fluorescence imaging plate reader instrument. NPS-2143 is incubated with cells for 1 minute before increasing the concentration of extracellular Ca²⁺ from 1.0 mM to 1.75 mM. NPS-2143 is tested individually at a concentration of 100 μg/mL (20 μM-80 μM) and those causing more than a 40% inhibition of the control response are considered to be biologically active. To determine the potencies (IC₅₀) of NPS-2143 with biological activity, concentration-response curves are obtained and then, as an initial assessment of selectivity, the effects of NPS-2143 on [Ca²⁺]i evoked by other G protein-coupled receptors are examined at a concentration several times their IC₅₀. Wild-type HEK 293 cells (and HEK 293 4.0-7 cells) express receptors for thrombin, bradykinin, and ATP, which couple to the mobilization of intracellular Ca²⁺. These responses can be studied to quickly assess any nonselective action of compounds on G protein-coupled receptors. Additional assays for selectivity include HEK 293 cells engineered to express receptors most homologous in sequence and topology to the Ca²⁺ receptor. These include native or chimeric receptors for various metabotropic glutamate and γ-aminobutyric acid type B receptors (GABABRs). Chimeric receptors are created using partial sequences of metabotropic glutamate receptors and Ca²⁺ receptors, engineered to couple to activation of phospholipase C and release of intracellular Ca²⁺ in HEK 293 cells. NPS-2143 lacking pan-activity are then subjected to structural modifications and their potencies and selectivities monitored using these HEK 293 4.0-7 cell assays in an iterative process.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Administration^[1]

Rats: On the day of study, the rats are infused intravenously (0.1 mL/kg·min) for 120 min with NPS-2143 (0.1 μmol/kg·min) or vehicle, a 20% aqueous solution of 2-hydroxypropyl-β-cyclodextrin. Blood samples (0.5 mL) are collected before and at various times after the start of the infusion for measurements of plasma levels of PTH and Ca²⁺. To prevent excessive blood volume loss during the course of the experiment, for each blood sample the erythrocyte pellet is resuspended in an equal volume of normal rat plasma and reinjected. Plasma levels of Ca²⁺ are measured immediately after collection using a model 634 ionized calcium analyzer. PTH levels are measured using the Immutopics rat PTH(1-34) immunoradiometric assay kit.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (280 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Nemeth EF, et al. Calcilytic compounds: potent and selective Ca2+ receptor antagonists that stimulate secretion of parathyroid hormone. J Pharmacol Exp Ther. 2001 Oct;299(1):323-31. [Content Brief]

[2]. Rybczynska A, et al. Hypertensive effect of calcilytic NPS 2143 administration in rats. J Endocrinol. 2006 Oct;191(1):189-95. [Content Brief]

[3]. Ohsu T, et al. Involvement of the calcium-sensing receptor in human taste perception. J Biol Chem. 2010 Jan 8;285(2):1016-22 [Content Brief]

[4]. Nakajima S, et al. Calcium-sensing receptor mediates dietary peptide-induced CCK secretion in enteroendocrine STC-1 cells. Mol Nutr Food Res. 2012 May;56(5):753-60 [Content Brief]

[5]. Sun J, et al. Calcium-sensing receptor: a sensor and mediator of ischemic preconditioning in the heart. Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1309-17. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4455 mL	12.2273 mL	24.4546 mL	61.1366 mL
	5 mM	0.4891 mL	2.4455 mL	4.8909 mL	12.2273 mL
	10 mM	0.2445 mL	1.2227 mL	2.4455 mL	6.1137 mL
	15 mM	0.1630 mL	0.8152 mL	1.6303 mL	4.0758 mL
	20 mM	0.1223 mL	0.6114 mL	1.2227 mL	3.0568 mL
	25 mM	0.0978 mL	0.4891 mL	0.9782 mL	2.4455 mL
	30 mM	0.0815 mL	0.4076 mL	0.8152 mL	2.0379 mL
	40 mM	0.0611 mL	0.3057 mL	0.6114 mL	1.5284 mL
	50 mM	0.0489 mL	0.2445 mL	0.4891 mL	1.2227 mL
	60 mM	0.0408 mL	0.2038 mL	0.4076 mL	1.0189 mL
	80 mM	0.0306 mL	0.1528 mL	0.3057 mL	0.7642 mL
	100 mM	0.0245 mL	0.1223 mL	0.2445 mL	0.6114 mL

Keywords

NPS-2143

30 Cited Publications

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NPS-2143

GPCR/G Protein Compound Library

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Anti-Cardiovascular Disease Compound Library

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Publications Citing Use of MedChemExpress (MCE) NPS-2143

Biologische Aktivität

Chemical Information

Publications (30)

Lösungsmittel & Löslichkeit

Protokoll

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

NPS-2143

GPCR/G Protein Compound Library

Clinical Compound Library

Drug Repurposing Compound Library

Anti-Cardiovascular Disease Compound Library

Orally Active Compound Library

Targeted Diversity Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Highly Selective Inhibitors Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Drug Repurposing Compound Library Plus

Clinical Compound Library Plus

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Lactylation Compound Library

Publications Citing Use of MedChemExpress (MCE) NPS-2143

Biologische Aktivität

Chemical Information

Publications (30)

Lösungsmittel & Löslichkeit

Protokoll

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

NPS-2143 Related Classifications

Art. -Nr.: HY-10007