- Natural Products
- Plants
- Valerianaceae
- Nardostachys jatamansi (D. Don) DC.
Nardostachys jatamansi (D. Don) DC.
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Nardostachys jatamansi (D. Don) DC. (23)
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- Formula: C15H22O3
- Molecular Weight: 250.33
Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances.
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- Formula: C15H20O3
- Molecular Weight: 248.32
Kanshone C is a sesquiterpenoid of Nardostachys chinensis roots.
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- Formula: C16H24O10
- Molecular Weight: 376.36
Adoxosidic acid is a SERT enhancer can be extracted from N. jatamansi and can be used in antidepressant research.
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- Formula: C15H24
- Molecular Weight: 204.35
Valerena-4,7(11)-diene is a tranquilizer. Valerena-4,7(11)-diene suppresses stress-induced excitatory behaviors. Valerena-4,7(11)-diene is expressed via olfactory stimulation and pulmonary absorption.
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- Formula: C15H22O2
- Molecular Weight: 234.33
Nardoguaianone K, a guaiane-type compound, can be isolated from Nardostachys chinensis roots. Nardoguaianone K cam be used in the research of pancreatic cancer.
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- Formula: C15H22O2
- Molecular Weight: 234.33
Nardoguaianone J, a guaiane-type compound, can be isolated from Nardostachys chinensis roots. Nardoguaianone J can enhance SERT activity.
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- Formula: C32H34O8
- Molecular Weight: 546.61
Nardochalaristolone B is a natural sesquiterpene.
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- Formula: C15H22O3
- Molecular Weight: 250.33
Nardosinone (Standard) is the analytical standard of Nardosinone. This product is intended for research and analytical applications. Nardosinone, isolated from Nardostachys chinensis, is the first enhancer of the neuritogenic action of dbcAMP and staurosporine. Nardosinone may become a useful pharmacological tool for studying the mechanism of action of not only nerve growth factor (NGF) but also both the neuritogenic substances.
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- Formula: C15H22O3
- Molecular Weight: 250.33
2-Deoxokanshone L is a degradation product of Nardosinone (HY-N0380).
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- Formula: C12H16O2
- Molecular Weight: 192.25
2-Deoxokanshone M (Nardosinone acid) is a degradation product of Nardosinone (HY-N0380) and has potent vasodilatory activity.
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- Formula: C15H20O
- Molecular Weight: 216.32
Kanshone H (compound 6) is a sesquiterpene compound isolated from the underground parts of spikenard.
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- Formula: C15H22O4
- Molecular Weight: 266.33
Kanshone B (Compound 5) is isolated from the natural Nardostachys chinensis. Kanshone B shows inhibitory activity against LPS-induced NO production (IC50=11.5 μM) .
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- Formula: C12H16O3
- Molecular Weight: 208.25
Narchinol B (Compound 4) is a sesquiter penoid compound. Narchinol B has anti-inflammatory effects. Narchinol B works by inhibiting proinflammatory mediators, including prostaglandin E2 (PGE2), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2) proteins, as well as proinflammatory cytokines, such as interleukin-1b, IL-6, and tumor necrosis factor-α (TNF-α). Narchinol B significantly inhibits LPS-induced overproduction of NO in BV2 cells (IC50=2.43 μM) .
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- Formula: C14H18O2
- Molecular Weight: 218.29
Nardoaristolone B, a non-sesquiterpene compound isolated from the root of Nardostachys jatamansi, has protective effects on cardiomyocyte injury in neonatal rats.
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- Formula: C15H22O2
- Molecular Weight: 234.33
Debilon, a diterpene compound, is a natural product that could be isolated from the roots and rhizomes of Nardostachys chinensis.
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- Formula: C15H22O2
- Molecular Weight: 234.33
Kanshone A is a sesquiterpene isolated from the roots of Nardostachys chinensis (Valerianaceae). Kanshone A shows cytotoxic with an IC50 value of 7.0 µg/ml in P388 cells.
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- Formula: C15H22O2
- Molecular Weight: 234.33
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- Formula: C15H22O4
- Molecular Weight: 266.33
Secoaristolenedioic acid (Compound 1) is a sesquiterpene, which is found in ethanol extract of the roots and rhizomes of Nardostachys chinensis.
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- Formula: C15H24O2
- Molecular Weight: 236.35
Nardoeudesmol A is a natural product.
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