Kanshone B
Kanshone B (Compound 5) is isolated from the natural Nardostachys chinensis. Kanshone B shows inhibitory activity against LPS-induced NO production (IC50=11.5 μM) .
For research use only. We do not sell to patients.
- CAS No.: 115370-61-1
- Formula: C15H22O4
- Molecular Weight:266.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
11.5 μM
Compound: 5
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 24 hrs by Griess method
|
[PMID: 22079762] |
Chemical Information
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CAS No. 115370-61-1
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Molecular Weight 266.33
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Formula C15H22O4
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SMILES
C[C@@]12[C@@]3([H])[C@@](OOC3(C)C)([H])CC(C1=C[C@@H](C[C@H]2C)O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)