Peganum nigellastrum Bunge
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Peganum nigellastrum Bunge (4)
- Formula: C18H11N3O
- Molecular Weight: 285.30
Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity.
- Formula: C11H12N2
- Molecular Weight: 172.23
Desoxypeganine (Deoxypeganine), an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine can be used for alcohol abuse research.
- Formula: C11H12N2O2
- Molecular Weight: 204.23
Pegamine is a quinazoline-quinoline alkaloid that can be isolated from Peganum nigellastrum.
- Formula: C18H11N3O2
- Molecular Weight: 301.30
Luotonin F is an alkaloid found in the aerial parts of the P. nigellastrum Bunge. Luotonin F shows cytotoxic activity against mouse leukemia P-388 cells by inhibiting human topoisomerase II.
