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PF-CBP1 hydrochloride 

Cat. No.: HY-19999A Purity: 99.77%
Data Sheet SDS Handling Instructions

PF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain.

For research use only. We do not sell to patients.
PF-CBP1 hydrochloride Chemical Structure

PF-CBP1 hydrochloride Chemical Structure

CAS No. : 2070014-93-4

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $81 In-stock
5 mg $70 In-stock
10 mg $120 In-stock
25 mg $240 In-stock
50 mg $440 In-stock
100 mg $800 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

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Description

PF-CBP1 hydrochloride is a highly selective inhibitor of the CREB binding protein bromodomain. Target: CREB in vitro: PF-CBP1 modulates key inflammatory genes in primary macrophages. PF-CBP1 downregulates RGS4 in neurons, a target linked to Parkinson's disease. PF-CBP1 is 139-fold selective over BRD4 in the biochemical assays and >105-fold selective by ITC. F-CBP1 is also a potent inhibitor of EP300 (a result observed for other CBP inhibitors. [1]

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.9045 mL 9.5224 mL 19.0447 mL
5 mM 0.3809 mL 1.9045 mL 3.8089 mL
10 mM 0.1904 mL 0.9522 mL 1.9045 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

525.08

Formula

C₂₉H₃₇ClN₄O₃

CAS No.

2070014-93-4

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 34 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
PF-CBP1 hydrochloride
Cat. No.:
HY-19999A
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