1. Metabolic Enzyme/Protease
  2. Xanthine Oxidase
    Endogenous Metabolite
  3. Phytic acid

Phytic acid (Synonyms: myo-Inositol, hexakis(dihydrogen phosphate); Inositol hexaphosphate)

Cat. No.: HY-N0814
Handling Instructions

Phytic acid is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

For research use only. We do not sell to patients.

Phytic acid Chemical Structure

Phytic acid Chemical Structure

CAS No. : 83-86-3

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10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
250 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

Other Forms of Phytic acid:

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Description

Phytic acid is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects[1][2][3][4].

IC50 & Target

Xanthine oxidase[3]

In Vitro

Phytic acid (myo-Inositol) inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by phytic acid; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[3].

Clinical Trial
Molecular Weight

660.04

Formula

C₆H₁₈O₂₄P₆

CAS No.

83-86-3

SMILES

O=P(O)(O)O[[email protected]]([[email protected]]([[email protected]](OP(O)(O)=O)[[email protected]]1OP(O)(O)=O)OP(O)(O)=O)[[email protected]]([[email protected]]1OP(O)(O)=O)OP(O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 30 mg/mL (45.45 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5151 mL 7.5753 mL 15.1506 mL
5 mM 0.3030 mL 1.5151 mL 3.0301 mL
10 mM 0.1515 mL 0.7575 mL 1.5151 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[4]

Mice: MPTP (20 mg/kg/day, i.p.) is administrated for 5 days and animals are killed at 7 days later. Phytic acid (30 mg/kg/day, i.p.) or normalsaline is injected 4 days before MPTP administration and con-tinued until mice are killed, reaching a total treatment period of16 days[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Phytic acid
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