1. Metabolic Enzyme/Protease
  2. Xanthine Oxidase
    Endogenous Metabolite
  3. Phytic acid

Phytic acid (Synonyms: myo-Inositol, hexakis(dihydrogen phosphate); Inositol hexaphosphate)

Cat. No.: HY-N0814
Handling Instructions

Phytic acid is a major phosphorus storage compound of most seeds and cereal grains.

For research use only. We do not sell to patients.

Phytic acid Chemical Structure

Phytic acid Chemical Structure

CAS No. : 83-86-3

Size Price Stock Quantity
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
250 mg USD 50 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Other Forms of Phytic acid:

Top Publications Citing Use of Products
  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Phytic acid is a major phosphorus storage compound of most seeds and cereal grains.

In Vitro

Phytic acid, a major phosphorus storage compound of most seeds and cereal grains, contributes about 1 to 7% of their dry weight. It may account for more than 70% of the total kernel phosphorus. Phytic acid has the strong ability to chelate multivalent metal ions, especially zinc, calcium, and iron. The binding can result in very insoluble salts that are poorly absorbed from the gastrointestinal tract, which results in poor bioavailability of minerals. Phytic acid is also considered to be a natural antioxidant and is suggested to have potential functions of reducing lipid peroxidation and as a preservative in foods[1]. Phytic acid inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by phytic acid; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[2]. There has been observed an inhibition of tumor growth and induction of cell differentiation in the presence of phytic acid in a few cancer cell lines including colon, nipple, breast, prostate, cervix, liver, pancreas, melanoma and glioblastoma[3].

In Vivo

Phytic acid has a neuroprotective effect in MPTP-induced PD model and the neuroprotection is correlated with its anti-inflammatory effect which may be associated with suppression of pathways that involved in NF-κB and p-ERK. Phytic acid significantly inhibits MPTP-induced dopaminergic cell loss in the substantia nigra (SN). Moreover, using immunohistochemistry method and quantitative polymerase chain reaction (qPCR), microglial activation and inducible nitric oxide synthase (iNOS) are found to be markedly repressed by phytic acid[4].

Clinical Trial
Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 30 mg/mL (45.45 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5151 mL 7.5753 mL 15.1506 mL
5 mM 0.3030 mL 1.5151 mL 3.0301 mL
10 mM 0.1515 mL 0.7575 mL 1.5151 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Animal Administration
[4]

Mice: MPTP (20 mg/kg/day, i.p.) is administrated for 5 days and animals are killed at 7 days later. Phytic acid (30 mg/kg/day, i.p.) or normalsaline is injected 4 days before MPTP administration and con-tinued until mice are killed, reaching a total treatment period of16 days[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

660.04

Formula

C₆H₁₈O₂₄P₆

CAS No.

83-86-3

SMILES

O=P(O)(O)O[[email protected]]([[email protected]]([[email protected]](OP(O)(O)=O)[[email protected]]1OP(O)(O)=O)OP(O)(O)=O)[[email protected]]([[email protected]]1OP(O)(O)=O)OP(O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Phytic acid
Cat. No.:
HY-N0814
Quantity:

Phytic acid

Cat. No.: HY-N0814