1. Metabolic Enzyme/Protease
  2. Xanthine Oxidase
    Endogenous Metabolite
  3. Phytic acid dodecasodium salt hydrate

Phytic acid dodecasodium salt hydrate (Synonyms: myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate; Inositol hexaphosphate dodecasodium salt hydrate)

Cat. No.: HY-N0814A Purity: >98.0%
Handling Instructions

Phytic acid dodecasodium salt hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

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Phytic acid dodecasodium salt hydrate Chemical Structure

Phytic acid dodecasodium salt hydrate Chemical Structure

CAS No. : 123408-98-0

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Based on 1 publication(s) in Google Scholar

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Description

Phytic acid dodecasodium salt hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium salt hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium salt hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects[1][2][3][4].

IC50 & Target

Xanthine oxidase[3]

In Vitro

Phytic acid dodecasodium salt hydrate (myo-Inositol) inhibits the formation of uric acid from xanthine with an IC50 of about 30 mM. The generation of the superoxide is greatly affected by Phytic acid dodecasodium salt hydrate; the IC50 is about 6 mM, indicating that the superoxide generating domain of XO is more sensitive to phytic acid[3].

Clinical Trial
Formula

C₆H₁₈O₂₄P₆.XH₂O.₁₂Na

CAS No.

123408-98-0

SMILES

O=P(O[Na])(O[Na])O[[email protected]]1[[email protected]]([[email protected]]([[email protected]](OP(O[Na])(O[Na])=O)[[email protected]@H](OP(O[Na])(O[Na])=O)[[email protected]@H]1OP(O[Na])(O[Na])=O)OP(O[Na])(O[Na])=O)OP(O[Na])(O[Na])=O.[x].O.[12Na]

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Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 250 mg/mL

*"≥" means soluble, but saturation unknown.

References

Purity: >98.0%

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Phytic acid dodecasodium salt hydrate
Cat. No.:
HY-N0814A
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