2. Endocrinology

Endocrinology

Endocrinology

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Found in most species of the animal kingdom, the endocrine system consists of glands that secrete hormones, and receptors that detect and react to the hormones. In response to environmental stimuli, the endocrine system secretes hormones and uses them as chemical messengers to orchestrate physiological, developmental and reproductive changes that affect the entire body for a long period of time. In order to maintain the proper functioning of the body through its entire life cycle, the endocrine system utilizes a complex feedback mechanism to fine-tune the balance of hormones in the bloodstream. Even a slight disruption to endocrine system’s function can throw off the delicate balance of hormones in the human body and lead to an endocrine disorder, or endocrine disease, such as diabetes, adrenal insufficiency, hyper- or hypothyroidism, and polycystic ovary syndrome (PCOS).

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1895S1
    Levodropropizine-d5 98%
    Levodropropizine-d5 ((S)-(-)-Dropropizine-d5) is deuterium labeled Levodropropizine. Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent.
    Levodropropizine-d5
  • HY-N0132AR
    Synephrine hydrochloride (Standard) 5985-28-4 98%
    Synephrine (hydrochloride) (Standard) is the analytical standard of Synephrine (hydrochloride). This product is intended for research and analytical applications. Synephrine (Oxedrine) hydrochloride, an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine hydrochloride is a sympathomimetic compound and can be used for weight loss.
    Synephrine hydrochloride (Standard)
  • HY-N2037AR
    Higenamine hydrochloride (Standard) 11041-94-4 98%
    Higenamine (hydrochloride) (Standard) is the analytical standard of Higenamine (hydrochloride). This product is intended for research and analytical applications. Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases.
    Higenamine hydrochloride (Standard)
  • HY-N8460AR
    Cortisol sulfate sodium (Standard) 1852-36-4 98%
    Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin.
    Cortisol sulfate sodium (Standard)
  • HY-P0009S1
    Cetrorelix-d10 98%
    Cetrorelix-d10 (SB-75-d10) is deuterium labeled Cetrorelix. Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice.
    Cetrorelix-d10
  • HY-P0036S2
    Octreotide-d8 1240797-41-4 98%
    Octreotide-d8 (SMS 201-995-d8) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide-d8
  • HY-P0036S3
    Octreotide-13C9,15N 98%
    Octreotide-13C9,15N (SMS 201-995-13C9,15N) is 13C and 15N labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide-13C9,15N
  • HY-P0036S4
    Octreotide-d8 acetate 98%
    Octreotide-d8 (acetate) (SMS 201-995-d8 (acetate)) is deuterium labeled Octreotide. Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide-d8 acetate
  • HY-P990721
    Inpegsomatropin 2656386-75-1 98%
    Inpegsomatropin is a pegylated long-acting recombinant human growth hormone.
    Inpegsomatropin
  • HY-P991291
    XOMA 129 98%
    XOMA 129 is a human monoclonal antibody targeting INSR. XOMA 129 is an insulin receptor (IR) antagonist that inhibits the drop in blood glucose. XOMA 129 can be used in the study of hypoglycemia .
    XOMA 129
  • HY-P991677
    Efmirenpase alfa 2770242-54-9 98%
    Efmirenpase alfa is an Fc-ENPP1 fusion protein (human IgG1 Fc domain linked to a modified human ENPP1). Efmirenpase alfa has prolonged half-life and enhanced receptor affinity compared with native human ENPP1. Efmirenpase alfa can be used as an enzyme replacement therapy for ENPP1 deficiency such as arterial calcification and hypophosphatemic rickets research.
    Efmirenpase alfa
  • HY-RS29468
    Spaca1 Mouse Pre-designed siRNA Set A 98%
    Spaca1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for SPACA1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Components
    SPACA1 siRNA-1: 5 nmol (HPLC)
    SPACA1 siRNA-2: 5 nmol (HPLC)
    SPACA1 siRNA-3: 5 nmol (HPLC)
    siRNA Negative Control: 5 nmol (HPLC)
    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    Spaca1 Mouse Pre-designed siRNA Set A
  • HY-RS29489
    Eqtn Mouse Pre-designed siRNA Set A 98%
    Eqtn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eqtn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Components
    Eqtn siRNA-1: 5 nmol (HPLC)
    Eqtn siRNA-2: 5 nmol (HPLC)
    Eqtn siRNA-3: 5 nmol (HPLC)
    siRNA Negative Control: 5 nmol (HPLC)
    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    Eqtn Mouse Pre-designed siRNA Set A
  • HY-U00098R
    Prednisolone Tebutate (Standard) 7681-14-3
    Prednisolone Tebutate (Standard) is the analytical standard of Prednisolone Tebutate. This product is intended for research and analytical applications. Prednisolone tebutate is a synthetic glucocorticoid used as an antiinflammatory and immunosuppressant.
    Prednisolone Tebutate (Standard)
  • HY-U00399A
    Fiduxosin hydrochloride 208992-74-9 98%
    Fiduxosin hydrochloride (ABT 980) is a potent α1-adrenoceptor antagonist, with Ki of 0.160 nM, 24.9 nM, and 0.920 nM for α1a-, α1b-, and α1d-adrenoceptors, respectively.
    Fiduxosin hydrochloride
  • HY-W008769
    Ethychlozate 27512-72-7 98%
    Ethychlozate is a plant growth regulator on the promotion of flowering in citrus.
    Ethychlozate
  • HY-W014885
    Decyl acetate 112-17-4 98%
    Decyl acetate is a synthetic pheromone attracting male false codling moths (Cryptophlebia leucotreta).
    Decyl acetate
  • HY-W106688
    Triisopropyl phosphate 513-02-0 98%
    Triisopropyl phosphate inhibits TFF1 and EGR3 gene expression, exhibits anti-estrogenic activity that inhibits Estradiol (HY-B0141)-induced MCF-7 cell proliferation with an EC50 of 341 μM. Triisopropyl phosphate inhibits the estrogen response element (ERE)-stimulated luciferase activity in MVLN cells with an EC50 of 900 μM.
    Triisopropyl phosphate
  • HY-W150752
    Triphenylethylene 58-72-0
    Triphenylethylene is an aromatic hydrocarbon that possesses weak estrogenic activity. Triphenylethylene antiestrogens relax duodenal intestinal muscle via a mechanism that involves inhibition of L-type Ca2+ channels but not activation of K+ channels.
    Triphenylethylene
  • HY-W150928
    Tridecyl acetate 1072-33-9 98%
    Tridecyl acetate is a species-specific female sex pheromone isolated from Adoxophyes sp. (smaller tea tortrix, STT).
    Tridecyl acetate
Cat. No. Product Name / Synonyms Application Reactivity