2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7232
    Limocrocin 24112-57-0 98%
    Limochromin is a pigment produced by Streptomyces limosus that strongly inhibits the reverse transcriptase of avian myeloid leukemia virus (AMV). The inhibitory activity of limochromin is not affected by changes in the concentration of template-primer, substrate or carrier protein, but its inhibitory effect is significantly reduced when the concentration of AMV reverse transcriptase increases. Limochromin can be used to develop antiviral treatments.
    Limocrocin
  • HY-N7250
    (+)-trans-Isolimonene 5113-87-1 98%
    (+)-trans-Isolimonene is a natural monoterpene isolated from essential oil.
    (+)-trans-Isolimonene
  • HY-N7281
    Aphadilactone C 1522004-70-1 98%
    Aphadilactone C is a potent and selective DGAT-1 inhibitor with an IC50 of 0.46 μM. Aphadilactone C shows significant antimalarial activities with an IC50 value of 170 nM.
    Aphadilactone C
  • HY-N7329
    Corymbosin 18103-41-8 98%
    Corymbosin is a glucoside. Corymbosin can be isolated from the aerial parts of Ballota glandulosissima. Corymbosin also has antifungal flavonoid activity.
    Corymbosin
  • HY-N7330
    Integracin B 224186-05-4 98%
    Integracin B is a potent dimeric alkyl aromatic inhibitor of HIV-1 integrase discovered from the screening of fungal extracts using an in vitro assay. Integracin B inhibits both coupled and strand transfer activity of HIV-1 integrase.
    Integracin B
  • HY-N7430
    3-O-Methylellagic acid 51768-38-8 98%
    3-O-Methylellagic acid is a nature product that can be isolated from Myrciaria cauliflora, with anti-inflammatory activity. 3-O-Methylellagic acid shows an inhibitory effect on glucose transport assay. 3-O-Methylellagic acid has antibacterial activity, with a MIC of 32 μg/mL for Staph. Aureus ATCC 25923.
    3-O-Methylellagic acid
  • HY-N7454
    Anhydroerythromycin A 23893-13-2 98%
    Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.
    Anhydroerythromycin A
  • HY-N7505
    Norchelerythrine 6900-99-8 98%
    Norchelerythrine is an alkaloid isolated from the roots of Zanthoxylum capense with antibacterial activity against gram-positive and gram-negative bacteria. Norchelerythrine exhibits inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Enterococcus faecalis and Escherichia coli with MIC values >50 µg/mL.
    Norchelerythrine
  • HY-N7519
    5-(12Z-Heptadecenyl)-resorcinol 103462-06-2 98%
    5-(12Z-Heptadecenyl)-resorcinol serves as the main component of Antifungal mixtures. 5-(12Z-Heptadecenyl)-resorcinol can be isolated from mango peels. Antifungal mixtures composed of 5-(12Z-Heptadecenyl)-resorcinol exhibit activity against Alternaria alternata. 5-(12Z-Heptadecenyl)-resorcinol can be used in studies related to mango fruit black spot disease.
    5-(12Z-Heptadecenyl)-resorcinol
  • HY-N7572
    Eupatoriopicrin 6856-01-5 98%
    Eupatoriopicrin is an antitrypanosomic agent with an IC50 value of 1.2 μM (T. b. rhodesiense). Eupatoriopicrin is cytotoxic to L6 cells with an IC50 value of 1.6 μM.
    Eupatoriopicrin
  • HY-N7609
    Kipukasin D 948574-00-3 98%
    Kipukasin D is an natural nucleoside derived from Aspergillus versicolor with antibacterial activity.
    Kipukasin D
  • HY-N7647
    Methyl brevifolincarboxylate 154702-76-8 98%
    Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate has anti-oxidant activity. Methyl brevifolincarboxylate also inhibits platelet aggregation, lipid metabolism and inflammation.
    Methyl brevifolincarboxylate
  • HY-N7672
    Isoeuphorbetin 50886-61-8 98%
    Isoeuphorbetin, a dimeric coumarin isolated from Viola philippica, is a potent HCV protease inhibitor with an IC50 of 3.63 µg/mL.
    Isoeuphorbetin
  • HY-N7699
    D-Dimannuronic acid 34044-53-6 98%
    D-Dimannuronic acid is an alginate extract from brown algae which can be used to synthesize sulfated polymannuronate (SPMG)-derived oligosaccharides.
    D-Dimannuronic acid
  • HY-N7701
    L-Diguluronic acid 34044-54-7 98%
    L-Diguluronic acid is a linear polysaccharide copolymer composed of two L-guluronic acid (G) and can be used to from Alginate. Alginate is a generic name of unbranched polyanionic polysaccharides and can be used for the research of antifungal agents delivery carries.
    L-Diguluronic acid
  • HY-N7718
    (−)-Rugulosin 21884-45-7 98%
    (−)-Rugulosin is a fungal metabolite and an orally active anti-influenzal agent.
    (−)-Rugulosin
  • HY-N7739
    Lavandulyl senecioate 23960-07-8 98%
    Lavandulyl senecioate is a senecioyl ester of lavandulol.Lavandulyl senecioate’s (S)-enantiomer serves as the sex pheromone of the vine mealybug (Planococcus ficus). Lavandulyl senecioate can be used in research related to pest control.
    Lavandulyl senecioate
  • HY-N7788
    cis-2-Dodecenoic acid 55928-65-9 98%
    cis-2-Dodecenoic acid, originally discovered in Burkholderia cenocepacia, can interfere with the bacterial quorum sensing system and inhibit bacterial biofilm formation and virulence factor production.
    cis-2-Dodecenoic acid
  • HY-N7869
    Celangulin VII 337969-86-5 98%
    Celangulin VII is a β-dihydroagarofuran sesquiterpene polyol ester present in the root bark of Celastrus angulatus. Celangulin VII exhibits insecticidal and narcotic activities against the 4th-instar larvae of Mythimna separata. Celangulin VII can be used in insecticide-related research.
    Celangulin VII
  • HY-N7915
    Nepasaikosaponin K 405229-61-0 98%
    Nepasaikosaponin K is an anti-influenza agent. Nepasaikosaponin K shows an EC50 of 17.91 μM against influenza virus A/WSN/33 (H1N1) in 239T-Gluc cells.
    Nepasaikosaponin K
Cat. No. Product Name / Synonyms Application Reactivity