2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N15251
    Isovalerylspiramycin II 848080-53-5 98%
    Isovalerylspiramycin II is one of the core active components of the multi-component antibiotic Bitespiramycin. Isovalerylspiramycin II shows antibacterial activity and can be used for research of bacterial infection.
    Isovalerylspiramycin II
  • HY-N15263
    Cepafungin III 130743-09-8
    Cepafungin III is an acylpeptide antibiotic that can be isolated from the culture broth of Pseudomonas species. Cepafungin III exhibits inhibitory activity against yeast and fungi, and antitumor activity against P388 leukemia in mice, when mixed with Cepafungin I and II.
    Cepafungin III
  • HY-N15300
    Acremorin E 98%
    Acremorin E (Compound 7) is a terpenoid compound with antifungal activity. Acremorin E exerts its anti-C. gattiii effect by upregulating genes related to biosynthesis and RNA binding of ribosomes, as well as inhibiting RNA and nucleic acid metabolism and ATPase activity (MIC: 8 μg/mL).
    Acremorin E
  • HY-N15365
    Antcin B 163597-25-9 98%
    Antcin B is a SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) inhibitor. Antcin B binds to multiple key amino acid residues of 3CL Pro(such as Leu141, Asn142, Glu166, His163, etc.) through hydrogen bonds, salt bridges, and hydrophobic interactions, thereby inhibiting the activity of 3CL Pro, blocking the cleavage process of viral polyproteins, and suppressing the replication of the SARS-CoV-2 virus in host cells. Antcin B is promising for research of COVID-19.
    Antcin B
  • HY-N15479
    Nanangenine F
    Nanangenine F is a drimane sesquiterpenoid with weak antibacterial and anticancer activities. Nanangenine F inhibits Bacillus subtilis (ATCC 6633) with an IC50 of 78 µg/mL. Nanangenine F inhibits NS-1, DU-145, MCF-7 and human fibroblast NFF cells with IC50s of 49 µg/mL, 95 µg/mL, 49 µg/mL, and 84 µg/mL, respectively.
    Nanangenine F
  • HY-N15546
    Thaigranatumin H
    Thaigranatumin H is a limonoid compound that can be obtained from the fruit of the Thai mangrove plant.
    Thaigranatumin H
  • HY-N15548
    Armeniaspirol A 1206881-47-1
    Armeniaspirol A (Armeniaspirole A) is an antibacterial agent targeting Helicobacter pylori cell membranes. Armeniaspirol A induces membrane permeabilization, cytoplasmic leakage, and biofilm inhibition/eradication. Armeniaspirol A is promising for research of H. pylori infection.
    Armeniaspirol A
  • HY-N15550
    Armeniaspirol B 1206881-48-2 98%
    Armeniaspirol B is a selective antibiotic targeting Gram-positive pathogens, showing MIC values of 0.5 μg/mL against S. aureus Newman and 2.0 μg/mL against S. aureus USA300. Armeniaspirol B is promising for research of Gram-positive bacterial infections (e.g., MRSA, VRE infections).
    Armeniaspirol B
  • HY-N15551
    Armeniaspirol C 1206881-49-3
    Armeniaspirol C is a potent antibacterial agent targeting Gram-positive bacteria. Armeniaspirol C is is promising for research of infections caused by multidrug-resistant Gram-positive bacteria.
    Armeniaspirol C
  • HY-N15618
    Antiviral agent 68 87095-75-8
    Antiviral agent 68 (Compound 3) is a diarylheptanoid that can be isolated from Alpinia katsumadai. Antiviral agent 68 has weak inhibitory activity against the neuraminidase of influenza virus A/PR/8/34, with an IC50 of 29.75 μM.
    Antiviral agent 68
  • HY-N15619
    Pterygospermin 11054-42-5
    Pterygospermin is an antibiotic compound found in Moringa. Pterygospermin has antibacterial has fungicidal activity.
    Pterygospermin
  • HY-N15635
    Withacoagin 119539-81-0 98%
    Withacoagin is a withanolide that can be isolated from the roots of Withania coagulans. Withacoagin has various biological activites such as adaptogenic, anti-inflammatory, and antioxidant properties. Withacoagin regulates the activity of various enzymes and pathways related to oxidative stress and inflammation. Withacoagin can attenuates HIV-1 infection.
    Withacoagin
  • HY-N15640
    Filiformin 62311-75-5 98%
    Filiformin ((-)-Filiformin) is a sesquiterpene compound that can be isolated from Laurencia filiformis forma heteroclada. Filiformin exhibits certain cytotoxicity against P388 and BSC-1 cells. Filiformin has antimicrobial activity against Bacillus subtilis, Trichophyton mentagrophytes and Candida albicans. In addition, Filiformin can inhibit oxygen uptake in isolated rat liver mitochondria at a concentration of 150 μM.
    Filiformin
  • HY-N15643
    α-Mycolic acid (C80) 23040-84-8
    α-Mycolic acid (C80) is a structural lipid component of mycobacterial cell wall. α-Mycolic acid (C80) can be isolated from Mycobacterium tuberculosis Canetti. α-Mycolic acid (C80) significantly modulates membrane permeability and stability, promising for mycobacterium tuberculosis infection research.
    α-Mycolic acid (C80)
  • HY-N15644
    Mycolic acid IIa 23599-54-4
    Mycolic acid IIa is a structural lipid component of mycobacterial cell wall. Mycolic acid IIa can be isolated from Mycobacterium bovis BCG. Mycolic acid IIa significantly modulates membrane permeability and stability, promising for mycobacterium tuberculosis infection research.
    Mycolic acid IIa
  • HY-N15645
    α-Mycolic acid, keto cis 2260795-20-6
    α-Mycolic acid, keto cis is a structural lipid component of mycobacterial cell wall. α-Mycolic acid, keto cis can be isolated from Mycobacterium tuberculosis Canetti. α-Mycolic acid, keto cis significantly modulates membrane permeability and stability, promising for mycobacterium tuberculosis infection research.
    α-Mycolic acid, keto cis
  • HY-N15653
    Heveadride 39595-41-0 98%
    Heveadride is a fungal metabolite and an antifungal agent. Heveadride is active against various filamentous fungi and some human pathogenic yeasts. Heaveadride induces down-regulation of TNFα-induced NF-κB activity in human chronic myeloid leukemia cells with an IC50 of 82.7 μM.
    Heveadride
  • HY-N15655
    Ravenelin 479-44-7 98%
    Ravenelin is a xanthone that can be isolated from the endophytic fungus Exserohilum rostratum. Ravenelin exhibits antiprotozoal and antibacterial activity. Ravenelin is active against gram-positive bacterial strains. Ravenelin can be studied for hit-to-lead development, especially for Chagas Disease.
    Ravenelin
  • HY-N15661
    Maculine 524-89-0
    Maculine is a furoquinoline alkaloid that can be isolated from the bark of Helietta apiculate. Maculine has potent inhibitory effect on the growth of C. fragariae and L. gongliophoorus.
    Maculine
  • HY-N15662
    Coumestan 479-12-9
    Coumestan is a secondary metabolite found in leguminous plants and can be used as drug intermediate Coumestan can be used to synthesize various coumarin compounds such as Coumestrol (HY-N2335), Glytabastan B, and Coumestan Pks13 inhibitor. Coumestans can be used for the study of anti-cancer, anti-inflammatory, anti-oxidative, antibacterial, neuroprotective and organ protective.
    Coumestan
Cat. No. Product Name / Synonyms Application Reactivity