2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W749483
    Iprovalicarb-d8 98%
    Iprovalicarb-d8 is the deuterium labeled Iprovalicarb (HY-121766). Iprovalicarb (Fencaramid; SZX-0722) is a fungicide that can be used for the study of?fungal?diseases in the wine sector.
    Iprovalicarb-d8
  • HY-W750153
    Propoxur-d7 2140327-65-5 98%
    Propoxur-d7 is the deuterium labeled Propoxur. Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests.
    Propoxur-d7
  • HY-W750355
    Azadirachtin D 99399-65-2 98%
    Azadirachtin D is an insect growth regulator targeting ecdysone receptor (EcR) in insects. Azadirachtin D blocks the 20-hydroxyecdysone signaling pathway, leading to developmental arrest or death in insects. Azadirachtin D is promising for research of agricultural pests.
    Azadirachtin D
  • HY-W750724
    Spheroidenone 13836-70-9 98%
    Spheroidenone is an organic carbon source isolated from the metabolites of aerobic anoxic cells of marine dinoflagellates.
    Spheroidenone
  • HY-W750848
    Raja 42-d10 2469575-54-8 98%
    Raja 42-d10 is the deuterium labeled Raja 42 (HY-W749146). Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains.
    Raja 42-d10
  • HY-W751002
    Orthosporin 118063-79-9 98%
    Orthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity.
    Orthosporin
  • HY-W751350
    Cyclobenzaprine-d6 1261396-60-4 98%
    Cyclobenzaprine-d6 is the deuterium labeled Cyclobenzaprine. Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT2 receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases.
    Cyclobenzaprine-d6
  • HY-W751460
    (R)-(-)-Curcumene 4176-17-4 98%
    (R)-(-)-Curcumene is a 7-epizingiberene derivative and repellent. (R)-(-)-Curcumene can be derived from Tomato. (R)-(-)-Curcumene repells B. tabaci.
    (R)-(-)-Curcumene
  • HY-W751750
    Urethane-13C,15N 98%
    Urethane-13C,15N (Ethyl carbamate-13C,15N) is the 13C- and 15N-labeled Urethane (HY-B1207). Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro.
    Urethane-13C,15N
  • HY-W752451
    Amenamevir-d6 98%
    Amenamevir-d6 (ASP2151-d6) is the deuterium labeled Amenamevir (HY-14809). Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC50 of 14 ng/mL.
    Amenamevir-d6
  • HY-W753521
    Deleobuvir sodium 1370023-80-5 98%
    Deleobuvir sodium (BI 207127 sodium) is a non-nucleoside hepatitis C virus NS5B polymerase inhibitor with anti-hepatitis C virus activity.
    Deleobuvir sodium
  • HY-W754608
    EIDD 1931-13C,15N2 98%
    EIDD 1931-13C,15N2 (β-D-N4-Hydroxycytidine-13C,15N2) is the 13C- and 15N-labeled EIDD 19312 (HY-125033). EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent?anti-virus agent. EIDD-1931 effectively inhibits the replication activity of?venezuelan equine encephalitis?virus (VEEV),?Chikungunya?virus (CHIKV) and?hepatitis?C virus (HCV)
    EIDD 1931-13C,15N2
  • HY-W754691
    Glaziovine 6808-72-6 98%
    Glaziovine is an antiviral agent found in Hypserpa nitida. Glaziovine exhibits significant inhibitory activity against HBV, capable of suppressing hepatitis B virus surface antigen (HBsAg) secretion in Hep G2.2.15 cells transfected with HBV, with an IC50 of 8 nM.
    Glaziovine
  • HY-W756467
    Antibacterial agent 265-13C,d3 2733149-80-7 98%
    Antibacterial agent 265-13C,d3 (1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid-13C,d3) is the deuterium labeled and 13C-labeled Antibacterial agent 265 (HY-W018629). Antibacterial agent 265 (Compound 2) is an antibacterial agent. Antibacterial agent 265 shows antibacterial activity against Staphylococcus Aureus, Micrococcus Luteus, Bacillus subtilis, gram-negative Escherichia coli, Pseudomonas aeruginosa and Flavobacterium devorans.
    Antibacterial agent 265-13C,d3
  • HY-W758425
    1-Tetradecanol-d7 98%
    1-Tetradecanol-d7 is the deuterium labeled 1-Tetradecanol (HY-W004294). 1-Tetradecanol is a straight-chain saturated fatty alcohol and antibacterial agent. 1-Tetradecanol can be isolated from Myristica fragrans. 1-Tetradecanol possesses antibacterial and anti-inflammatory (periodontitis) activity.
    1-Tetradecanol-d7
  • HY-W760546
    SARS-CoV-2 3CLpro-IN-15 3156-41-0 98%
    SARS-CoV-2 3CLpro-IN-15 (compound a) is a beta-nitrostyrene coronavirus SARS-CoV-2 inhibitor that targets the SARS-CoV-2 3CL protease (3CLpro). SARS-CoV-2 3CLpro-IN-15 inhibits viral replication and transcription and plays a key role in the discovery of anti-COVID-19 lead compounds.
    SARS-CoV-2 3CLpro-IN-15
  • HY-W762018
    2,3,4,6,7,8-Hexachlorodibenzofuran 60851-34-5 98%
    2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 2,3,4,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 0.687 and 0.575 nM, respectively).
    2,3,4,6,7,8-Hexachlorodibenzofuran
  • HY-W765261
    Eprinomectin B1a-13C,d3 98%
    Eprinomectin B1a-13C,d3 is the deuterium and 13C labeled Eprinomectin B1a (HY-N8483). Eprinomectin B1a is a Eprinomectin (HY-12643) metabolite (an antiparasitic compound).
    Eprinomectin B1a-13C,d3
  • HY-W765997
    Didanosine-13C2,15N 98%
    Didanosine-13C2,15N (2',3'-Dideoxyinosine-13C2,15N; ddI-13C2,15N) is the 13C- and 15N-labeled labeled Didanosine (HY-B0249). Didanosine (2',3'-Dideoxyinosine; ddI) is a a potent and orally active dideoxynucleoside analogue, and also is a potent nucleoside reverse transcriptase inhibitor. Didanosine shows antiretroviral activity for HIV.
    Didanosine-13C2,15N
  • HY-W766078
    1-beta-D-Arabinofuranosyluracil-13C,15N2 98%
    1-beta-D-Arabinofuranosyluracil-13C,15N2 (1-b-D-Arabinofuranosyluracil-13C,15N2; Uracil 1-β-D-arabinofuranoside-13C,15N2) is the 13C- and 15N-labeled labeled 1-beta-D-Arabinofuranosyluracil (HY-N6652). 1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has demonstrated a diverse bioactivity profile including anti-inflammatory activity, analgesic and vasodilation properties. 1-beta-D-Arabinofuranosyluracil reduces a proliferation of mouse lymphoma cells.
    1-beta-D-Arabinofuranosyluracil-13C,15N2
Cat. No. Product Name / Synonyms Application Reactivity