2. Infection

Infection

Infection

Related Products

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-124365
    Rhamnetin tetraacetate 16280-26-5 98%
    Rhamnetin tetraacetate (compound 4) is a xanthone compound with antiplatelet activity. Rhamnetin tetraacetate inhibited platelet aggregation induced by arachidonic acid.
    Rhamnetin tetraacetate
  • HY-124431
    Kikumycin A 37913-77-2 98%
    Kikumycin A is an antibiotic, which can be generated from Streptomyces. Kikumycin A exhibits antibacterial activity against Gram-positive and Gram-negative bacteria. Kikumycin A exhibits antitrichomonal activity, with MIC of 25 μg/mL for Trichomonas foetus.
    Kikumycin A
  • HY-124469
    UM-C162 1799734-10-3 98%
    UM-C162, a benzimidazole derivative, can rescue nematodes from a S. aureus infection. UM-C162 prevents the formation of biofilm without interfering with bacterial viability. UM-C162 mediates the disruption of S. aureus hemolysins, proteases and clumping factors production. UM-C162 has the potential to be used as an anti-virulence agent to control S. aureus infections.
    UM-C162
  • HY-124477
    Stachybotrylactam 163391-76-2 98%
    Stachybotrylactam (17) is a phenylspirodrimane isolated from Stachybotrys chartarum with antihyperlipidemic activity. Stachybotrylactam also has antiviral activity.
    Stachybotrylactam
  • HY-124485
    Nitroscanate 19881-18-6
    Nitroscanate is an anthelmintic that has a calming effect on animals.
    Nitroscanate
  • HY-124508
    Lambertellin 28980-51-0 98%
    Lambertellin is an effective antibiotic that can be used as a bactericide and as a fungicide. Lambertellin exerts its anti-inflammatory effect in LPS (HY-D1056)-stimulated RAW 264.7 macrophage cells by modulating the activation of the MAPK and NF-κB signaling pathways.
    Lambertellin
  • HY-124509
    Pyrocoll 484-73-1 98%
    Pyrocoll is a bacterial metabolite originally isolated from Streptomyces. It inhibits the growth of A. aurescens, A. globiformis, A. oxydans, A. pascens, and R. erythropolis bacteria (MICs=10, 1, 10, 3, and 10 μg/mL, respectively) and HMO2, HepG2, and MCF-7 cancer cells (GI50s=0.28, 0.42, and 2.2 μg/mL, respectively) in vitro. Pyrocoll is also active against P. falciparum and T. rhodesiense (IC50s=1.19 and 1.97 μg/mL, respectively).
    Pyrocoll
  • HY-124522
    (E)-Metominostrobin 133408-50-1 98%
    (E)-Metominostrobin is a strobilurin fungicide that can be used for pest control during strawberry cultivation.
    (E)-Metominostrobin
  • HY-124545
    N,N-Diethylbenzamide 1696-17-9
    N,N-Diethylbenzamide (Benzoyldiethylamine) is a mosquito repellent with highly effective mosquito-repellent properties.
    N,N-Diethylbenzamide
  • HY-124590
    IDX-17119 1987906-92-2 98%
    IDX-17119 is a non-nucleoside HCV NS5B RdRp inhibitor with an IC50 of 0.4 nM.
    IDX-17119
  • HY-124598
    MRL-1237 276704-21-3 98%
    MRL-1237 is an inhibitor of the replication of several enteroviruses targeting the non-structural protein 2C of the virus. MRL-1237 shows effective inhibition against poliovirus and various other enteroviruses. MRL-1237 does not inhibit the NTPase (ATPase) activity of 2C protein. MRL-1237 can be used for the research of infection.
    MRL-1237
  • HY-124777
    NPD4456 859668-98-7 98%
    NPD4456 (Compound 3) is a 3-phenylcoumarin Vpr inhibitor. NPD4456 binds to Vpr in a competitive manner. NPD4456 inhibits HIV-1 viral infection.
    NPD4456
  • HY-12479B
    Epetraborole (R-mandelate) 1234563-15-5 98%
    Epetraborole R-mandelate is a novel leucyl-tRNA synthetase (LeuRS) inhibitor (IC50=0.31 μM), thereby inhibiting protein synthesis. Epetraborole R-mandelate can be used in multidrug-resistant gram-negative pathogens infection research.
    Epetraborole (R-mandelate)
  • HY-124870
    N.41 357441-99-7 98%
    N.41 is an antiviral agent. N.41 protects APOBEC3G (an antiviral factor) from HIV Vif protein-mediated degradation. N.41 inhibits the Vif-A3G interaction and increases cellular A3G levels and incorporation of A3G into virions, thereby attenuating virus infectivity in a Vif-dependent manner. N.41 inhibits HIV-1 viral replication in PBMCs (IC50: 8.4 μM).
    N.41
  • HY-124879
    MF 961 138372-62-0 98%
    MF 961 is a quinolone biocide. The MIC50 values ​of MF 961 against E. coli, Klebsiella sp., Enterobacter sp., Citrobacter sp., Citrobacter sp., and Shlgella sp. are all in the range of 0-25 mg/L.
    MF 961
  • HY-124920
    Methiocarb 2032-65-7 98%
    Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals.
    Methiocarb
  • HY-125042
    Sarothralin G 130756-15-9 98%
    Sarothralin G is an antibacterial compound isolated from Hypericum japonicum Thunb. (Japanese spurfle). The structure of Sarothralin G contains phenolic and aromatic acid moieties and shows excellent antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis and Nocardia spp., which is stronger than Sarothralen A, B and Saroaspidin A, B, C. Sarothralin G exhibits significant antibacterial potential.
    Sarothralin G
  • HY-125048
    Racemomycin B 3776-37-2 98%
    Racemomycin B (229-B; Streptothricin D), the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three β-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of β-lysine groups.
    Racemomycin B
  • HY-125066
    Reveromycin B 144860-68-4 98%
    Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells (IC50=6 μg/mL) and exhibits pH-dependent antifungal activity against C. albicans (MICs=15.6 and >500 μg/mL at pH 3.0 and 7.4, respectively). Unlike reveromycin A and reveromycin C, reveromycin B does not inhibit proliferation of KB and K562 cells.
    Reveromycin B
  • HY-125070
    Saframycin C 66082-29-9 98%
    Racemomycin C is an analog of the antibiotic soramycin and is probably the 0-methyl derivative of racemomycin B.
    Saframycin C
Cat. No. Product Name / Synonyms Application Reactivity