2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-105840R
    Dichloramine-T (Standard) 473-34-7
    Dichloramine-T (Standard) is the analytical standard of Dichloramine-T (HY-105840). This product is intended for research and analytical applications. Dichloramine-T is a strong oxidizer and disinfectant, with strong oxidation and sterilization. Dichloramine-T is also widely used in the medical and health field for disinfection and sterilization operations.
    Dichloramine-T (Standard)
  • HY-106005R
    MMV390048 (Standard) 1314883-11-8
    MMV390048 (Standard) is the analytical standard of MMV390048 (HY-106005). This product is intended for research and analytical applications. MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent.
    MMV390048 (Standard)
  • HY-106161R
    Rupintrivir (Standard) 223537-30-2 98%
    Rupintrivir (Standard) is the analytical standard of Rupintrivir (HY-106161). This product is intended for research and analytical applications. Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC50 of 0.023 μM. Rupintrivirvr shows immune-modulatory effect.
    Rupintrivir (Standard)
  • HY-106282R
    BIT-225 (Standard) 917909-71-8
    BIT-225 (Standard) is the analytical standard of BIT-225 (HY-106282). This product is intended for research and analytical applications. BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM).
    BIT-225 (Standard)
  • HY-106296R
    WIN 54954 (Standard) 107355-45-3
    WIN 54954 (Standard) is the analytical standard of WIN 54954. This product is intended for research and analytical applications. WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.
    WIN 54954 (Standard)
  • HY-106350A
    Cefpimizole sodium 85287-61-2 98%
    Cefpimizole (U-63196E) sodium is a broad-spectrum cephalosporin antibiotic. Cefpimizole sodium inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole sodium augments phagocytosis of macrophages and neutrophils.
    Cefpimizole sodium
  • HY-106382R
    PMEDAP (Standard) 113852-41-8
    PMEDAP (Standard) is the analytical standard of PMEDAP (HY-106382). This product is intended for research and analytical applications. PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality.
    PMEDAP (Standard)
  • HY-106506R
    Desciclovir (Standard) 84408-37-7 98%
    Desciclovir (Standard) is the analytical standard of Desciclovir. This product is intended for research and analytical applications. Desciclovir is a potent and orally active proagent of the antiherpetic agent Acyclovir (ACV). Desciclovir is converted to acyclovir in vivo by xanthine oxidase.
    Desciclovir (Standard)
  • HY-106541R
    Neticonazole (Standard) 130726-68-0 98%
    Neticonazole (Standard) is the analytical standard of Neticonazole. This product is intended for research and analytical applications. Neticonazole is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole has anti-infection and anti-cancer effects.
    Neticonazole (Standard)
  • HY-106571R
    Cefteram pivoxil (Standard) 82547-81-7
    Cefteram pivoxil (Standard) is the analytical standard of Cefteram pivoxil. This product is intended for research and analytical applications. Cefteram pivoxil (Ro 19-5248), an orally active cephalosporin antibiotic, is used for bacterial infections.
    Cefteram pivoxil (Standard)
  • HY-106634R
    Mitoguazone (Standard) 459-86-9
    Mitoguazone (Standard) is the analytical standard of Mitoguazone. This product is intended for research and analytical applications. Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment.
    Mitoguazone (Standard)
  • HY-106662R
    Chloroquinoxaline sulfonamide (Standard) 97919-22-7 98%
    Chloroquinoxaline sulfonamide (Standard) is the analytical standard of Chloroquinoxaline sulfonamide. This product is intended for research and analytical applications. Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle. Antitumor activity.
    Chloroquinoxaline sulfonamide (Standard)
  • HY-106755R
    Tucaresol (Standard) 84290-27-7 98%
    Tucaresol (Standard) is the analytical standard of Tucaresol. This product is intended for research and analytical applications. Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti-HIV effect.
    Tucaresol (Standard)
  • HY-106852A
    KP 736 sodium 133686-28-9 98%
    KP 736 sodium is a broad-spectrum antibacterial agent. KP 736 sodium exhibits excellent broad-spectrum anti Gram negative bacterial activity in vitro, especially effective against Pseudomonas aeruginosa and multiple drug-resistant bacteria. KP 736 sodium can be used for research on bacterial infections.
    KP 736 sodium
  • HY-106859R
    Letrazuril (Standard) 103337-74-2 98%
    Letrazuril (Standard) is the analytical standard of Letrazuril (HY-106859). This product is intended for research and analytical applications. Letrazuril is an anti-HIV agent.
    Letrazuril (Standard)
  • HY-107033R
    Tetroxoprim (Standard) 53808-87-0 98%
    Tetroxoprim (Standard) is the analytical standard of Tetroxoprim. This product is intended for research and analytical applications. Tetroxoprim is an antimicrobial DHFR inhibitor.
    Tetroxoprim (Standard)
  • HY-107075A
    WCK-1152 1332393-03-9 98%
    WCK-1152 is a fluoroquinolone antibacterial agent. WCK-1152 is active against resistant pathogens bearing mutations of DNA gyrase and/or topoisomerase IV which also express efflux pumps. WCK-1152 can be used for the research of infection, such as respiratory infections caused by resistant pneumococci and staphylococci.
    WCK-1152
  • HY-107123R
    TMC310911 (Standard) 1000287-05-7 98%
    TMC310911 (Standard) (ASC-09 (Standard)) is the analytical standard of TMC310911 (HY-107123). This product is intended for research and analytical applications. TMC310911 is a potent and orally active HIV type-1 (HIV-1) protease inhibitor with EC50 values ranged from 2.2 nM to 14.2 nM for wild-type HIV-1. TMC310911 has potent activity against a wide spectrum of recombinant HIV-1 isolates. TMC310911 has strong antiviral activity.
    TMC310911 (Standard)
  • HY-107329R
    Cefathiamidine (Standard) 33075-00-2
    Cefathiamidine (Standard) is the analytical standard of Cefathiamidine. This product is intended for research and analytical applications. Cefathiamidine is a first-generation cephalosporin antibacterial agent and is used to treat infections caused by susceptible bacteria. Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis[1][2].
    Cefathiamidine (Standard)
  • HY-107373R
    β-Chloro-L-alanine (Standard) 2731-73-9
    β-Chloro-L-alanine (Standard) (L-β-Chloroalanine (Standard)) is the analytical standard of β-Chloro-L-alanine (HY-107373). This product is intended for research and analytical applications. β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.
    β-Chloro-L-alanine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity