2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-131130A
    Neomycin C hexaacetate
    Neomycin C hexaacetate is an impurity of Neomycin (HY-150520) and a stereoisomer of Neomycin B (HY-17624). Neomycin C hexaacetate exerts in vitro antimicrobial activity against Staphylococcus epidermidis and Staphylococcus aureus. Neomycin C hexaacetate can be used for the research of bacterial infection.
    Neomycin C hexaacetate
  • HY-131146R
    AMOZ (Standard) 43056-63-9 98%
    AMOZ (Standard) is the analytical standard of AMOZ. This product is intended for research and analytical applications. AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used
    AMOZ (Standard)
  • HY-131150R
    Ristomycin sulfate (Standard) 11140-99-1
    Norfenefrine (hydrochloride) (Standard) is the analytical standard of Norfenefrine (hydrochloride). This product is intended for research and analytical applications. Norfenefrine hydrochloride is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence.
    Ristomycin sulfate (Standard)
  • HY-131165R
    Amoxicillin trihydrate mixture with potassium clavulanate (4:1) (Standard) 98%
    Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (Standard) is the analytical standard of Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1). This product is intended for research and analytical applications. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.
    Amoxicillin trihydrate mixture with potassium clavulanate (4:1) (Standard)
  • HY-131546R
    Levofloxacin Q-acid (Standard) 100986-89-8 98%
    Levofloxacin Q-acid (Standard) is the analytical standard of Levofloxacin Q-acid. This product is intended for research and analytical applications.
    Levofloxacin Q-acid (Standard)
  • HY-131611R
    6-Azuridine (Standard) 54-25-1 98%
    6-Azuridine (Standard) is the analytical standard of 6-Azuridine. This product is intended for research and analytical applications. 6-Azuridine (6-Azauridine) is an orally active purine nucleoside analogue. 6-Azuridine activates autophagic flux, induces Apoptosis that depends on AMPK and p53. 6-Azuridine exhibit both antitumor and antiviral activities.
    6-Azuridine (Standard)
  • HY-13238S2
    Dolutegravir-d5 2249814-82-0 98%
    Dolutegravir-d5 is deuterium labeled Dolutegravir. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM).
    Dolutegravir-d5
  • HY-132508S
    Etravirine-d8 1142096-06-7 98%
    Etravirine-d8 is the deuterium labeled Etravirine. Etravirine (R165335) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
    Etravirine-d8
  • HY-133004R
    Fenbutatin oxide (Standard) 13356-08-6
    Fenbutatin oxide (Standard) is the analytical standard of Fenbutatin oxide. This product is intended for research and analytical applications. Fenbutatin oxide is an organotin acaricide.
    Fenbutatin oxide (Standard)
  • HY-133216R
    Bupirimate (Standard) 41483-43-6
    Bupirimate (Standard) is the analytical standard of Bupirimate (HY-133216). This product is intended for research and analytical applications. Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew.
    Bupirimate (Standard)
  • HY-134033A
    2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium 98%
    2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium (2'-fluoro dATP) is a fluorinated derivative of ATP (HY-B2176). 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium is a substrate and an inhibitor for E.coli DNA-dependent RNA polymerase, with a Ki of 200 µM.
    2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium
  • HY-134116R
    Isoflupredone acetate (Standard) 338-98-7 98%
    Isoflupredone acetate (Standard) is the analytical standard of Isoflupredone acetate. This product is intended for research and analytical applications. Isoflupredone acetate is a corticosteroids with anti-inflammatory activity. Isoflupredone acetate can be used for research ketosis, musculoskeletal disorders, hypersensitivity, infections, inflammatory diseases in cows, horse, pigs, et al..
    Isoflupredone acetate (Standard)
  • HY-134248A
    Tubercidin 5'-triphosphate tetrasodium 98%
    Tubercidin 5'-triphosphate (7-Deazaadenosine 5'-triphosphate) tetrasodium, a nucleoside analog, is an active metabolite of Tubercidin (HY-100126).
    Tubercidin 5'-triphosphate tetrasodium
  • HY-134372A
    Bis-Br-ANT-ATP tetrasodium 98%
    Bis-Br-ANT-ATP (tetrasodium) is a fluorescent derivative of adenosine-5’-triphosphate (ATP) (HY-B2176). Bis-Br-ANT-ATP (tetrasodium) selectively inhibits B. pertussis adenylyl cyclase toxin CyaA (Ki: 12.6 nM). Bis-Br-ANT-ATP (tetrasodium) can be used in Whooping cough research.
    Bis-Br-ANT-ATP tetrasodium
  • HY-134373A
    Bis-Cl-ANT-ATP tetrasodium 98%
    Bis-Cl-ANT-ATP (tetrasodium) is a fluorescent ATP derivative, which undergo spontaneous isomerization. Bis-Cl-ANT-ATP (tetrasodium) selectively inhibits B. pertussis Adenylyl Cyclase (AC) toxin CyaA over mammalian AC1, AC2, and AC5 (Kis = 16, 1,700, 2,400, and 1,600 nM, respectively). Bis-Br-ANT-ATP (tetrasodium) can be used in the study of whooping cough.
    Bis-Cl-ANT-ATP tetrasodium
  • HY-13451AS
    Finafloxacin-d4 hydrochloride 2012598-36-4 98%
    Finafloxacin-d4 (hydrochloride) is deuterium-labeled Finafloxacin (hydrochloride) (HY-13451A).
    Finafloxacin-d4 hydrochloride
  • HY-134635R
    Dehydrozingerone (Standard) 1080-12-2 98%
    Dehydrozingerone (Standard) is the analytical standard of Dehydrozingerone. This product is intended for research and analytical applications. Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM.
    Dehydrozingerone (Standard)
  • HY-134666A
    Dioctatin A hydrochloride
    Dioctatin A hydrochloride is a metabolite of Streptomyces and an inhibitor of human dipeptidyl aminopeptidase II. Dioctatin A hydrochloride can inhibit aflatoxin production by Aspergillus parasiticus with an IC50 of 4.0 μM. Dioctatin A hydrochloride can reduce the mRNA levels of aflatoxin biosynthetic genes and the regulatory gene aflR, inhibit conidiation and decrease the mRNA level of the brlA gene, and also promote kojic acid production. In addition, Dioctatin A hydrochloride can inhibit sterigmatocystin production. Dioctatin A hydrochloride has pleiotropic regulatory effects on the production and differentiation of fungal secondary metabolites.
    Dioctatin A hydrochloride
  • HY-134940S
    Quabodepistat-d7 98%
    Quabodepistat-d7 (OPC-167832-d7) is deuterium labeled Quabodepistat. Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with?an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis?caused by?Mycobacterium tuberculosis.
    Quabodepistat-d7
  • HY-134991A
    3'-Deoxy-GTP trisodium 98%
    3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, is a RNA chain terminator and suppresses RNA synthesis. 3'-Deoxy-GTP trisodium inhibits DENV NS5 RdRp (IC50: 0.02 μM).
    3'-Deoxy-GTP trisodium
Cat. No. Product Name / Synonyms Application Reactivity