1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-158148
    CSF1R-IN-23 2935480-17-2 98%
    CSF1R-IN-23 (Compound 7dri) is a selective inhibitor for colony-stimulating factor-1 receptor (CSF1R), with IC50 of 36.1 nM. CSF1R-IN-23 serves as antineuroinflammatory agent in mouse model. CSF1R-IN-23 is blood brain barrier (BBB) permeable.
    CSF1R-IN-23
  • HY-158159
    IL17A-IN-1 98%
    IL17A-IN-1 (compound 72) is an orally active Interleukin 17A inhibitor. IL17A-IN-1 can be used in the study of inflammatory and autoimmune diseases (plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, etc.), as well as cancer.
    IL17A-IN-1
  • HY-158163
    Herbicidal agent 4 3038564-39-2 98%
    Herbicidal agent 4 (compound V-2) is an auxinic herbicidal agent. Herbicidal agent 4 may also be an immune activator while upregulating the defense genes and increasing content of jasmonic acid.
    Herbicidal agent 4
  • HY-158167
    AhR agonist 5 3033281-95-4 98%
    AhR agonist 5 is an AHR agonist (EC50 = 6 nM). From patent WO2024061187A1, compound 5.
    AhR agonist 5
  • HY-158168
    AhR agonist 6 3033281-96-5 98%
    AhR agonist 6 (Compound 6) is an agonist for aryl hydrocarbon receptor (AhR), with an EC50 of 0.01 nM.
    AhR agonist 6
  • HY-158169
    AhR agonist 7 3033281-98-7 98%
    AhR agonist 7 (Compound 8) has a good activation activity against AhR (ECsub>50 = 13nM).
    AhR agonist 7
  • HY-158171
    Cbl-b-IN-17 98%
    Cbl-b-IN-17 (Example-40) is an inhibitor of Cbl-b with an IC50 value <100 nM.
    Cbl-b-IN-17
  • HY-158173
    Cbl-b-IN-19 98%
    Cbl-b-IN-19 (Compound 49) is an inhibitor for casitas B-lineage lymphoma b(Cbl-b), that inhibits Cbl-b phosphorylation with an IC50 < 100 nM.
    Cbl-b-IN-19
  • HY-158180
    A3AR agonist 4 3032475-23-0 98%
    A3AR agonist 4 is an A3 adenosine receptor (A3AR) agonist (Ki: 1.24 nM for hA3AR). A3AR agonist 4 inhibits cAMP production with an EC50 of 0.17 nM. A3AR agonist 4 can be used for research of inflammation and pain.
    A3AR agonist 4
  • HY-158181
    A3AR agonist 5 3032475-38-7 98%
    A3AR agonist 5 (Compound 6b) is a A3 adenosine receptor (A3AR) activator, with EC50 and Ki values of 0.14 nM and 6.36 nM for cAMP and hA3, respectively. A3AR agonist 5 can be used in pain and inflammatory research.
    A3AR agonist 5
  • HY-158205
    HPO-DAEE 1895934-61-8 98%
    HPO-DAEE (4-Hydroperoxy-2-decenoic acid ethyl ester) elicits nuclear accumulation of Nrf2 and activated antioxidant response element (ARE). HPO-DAEE induces antioxidant genes upregulation (eg: HO-1) through Nrf2-ARE signaling. HPO-DAEE induces reactive oxygen species generation. HPO-DAEE also inhibits histone deacetylase and upregulate expression of extracellular superoxide dismutase via histone acetylation. HPO-DAEE protects against 6-hydroxydopamine-induced cell death via activation of Nrf2-ARE and eIF2α-ATF4 pathways.
    HPO-DAEE
  • HY-158267
    Enrofloxacin/OVA 98%
    Enrofloxacin/OVA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Enrofloxacin/OVA
  • HY-158268
    4-Hydroxynonenal/BSA 98%
    4-Hydroxynonenal/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    4-Hydroxynonenal/BSA
  • HY-158270
    Ethambutol-KLH 98%
    Ethambutol-KLH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Ethambutol-KLH
  • HY-158272
    Penicillin/OVA 98%
    Penicillin/OVA is a conjugate of penicillin and Ovalbumins, that is utilized as an antigen in immunological research. Penicillin/OVA causes IgE-dependent anaphylactic response to penicillin in mice.
    Penicillin/OVA
  • HY-158273
    2,4-D/BSA 98%
    2,4-D/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    2,4-D/BSA
  • HY-158274
    Gibberellins/BSA 98%
    Gibberellins/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Gibberellins/BSA
  • HY-158275
    Rifampin/BSA 98%
    Rifampin/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Rifampin/BSA
  • HY-158276
    Rifampin/KLH 98%
    Rifampin/KLH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Rifampin/KLH
  • HY-158277
    Streptomycin/BSA 98%
    Streptomycin/BSA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Streptomycin/BSA
Cat. No. Product Name / Synonyms Application Reactivity