Cbl-b-IN-17
Cbl-b-IN-17 (Example-40) is an inhibitor of Cbl-b with an IC50 value <100 nM.
For research use only. We do not sell to patients.
- Formula: C28H31F3N6O
- Molecular Weight:524.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: <100 nM (Cbl-b)[1].
Chemical Information
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Molecular Weight 524.58
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Formula C28H31F3N6O
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SMILES
O=C1N(C2=CC=CC(C(C3CCC3)C4=NN=CN4C)=C2)C=NC5=C1C=C(CNCC(C)C)C=C5C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)