2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-174611
    Human IL2RA mRNA 98%
    Human IL2RA mRNA encodes the human interleukin 2 receptor subunit alpha (IL2RA) protein, a receptor for interleukin-2. IL2RA is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
    Human IL2RA mRNA
  • HY-174612
    Human IL27RA mRNA 98%
    Human IL27RA mRNA encodes the human interleukin 27 receptor subunit alpha (IL27RA) protein, a protein that is similar to the mouse T-cell cytokine receptor (Tccr) at the amino acid level. IL27RA is predicted to be a glycosylated transmembrane protein.
    Human IL27RA mRNA
  • HY-174613
    Human IL27 mRNA 98%
    Human IL27 mRNA encodes the human interleukin 27 (IL27) protein, one of the subunits of a heterodimeric cytokine complex. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity and induce isotype switching in B-cells.
    Human IL27 mRNA
  • HY-174614
    Human IL26 mRNA 98%
    Human IL26 mRNA encodes the human interleukin 26 (IL26) protein, a member of the IL10 family of cytokines. IL26 is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri.
    Human IL26 mRNA
  • HY-174615
    Human IL24 mRNA 98%
    Human IL24 mRNA encodes the human interleukin 24 (IL24) protein, a member of the IL10 family of cytokines. IL24 can induce apoptosis selectively in various cancer cells.
    Human IL24 mRNA
  • HY-174616
    Human IL23R mRNA 98%
    Human IL23R mRNA encodes the human interleukin 23 receptor (IL23R) protein, a subunit of the receptor for IL23A/IL23. IL23R pairs with the receptor molecule IL12RB1/IL12R beta1, and both are required for IL23A signaling.
    Human IL23R mRNA
  • HY-174617
    Human IL23A mRNA 98%
    Human IL23A mRNA encodes the human interleukin 23A (IL23A) protein, a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23A associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity.
    Human IL23A mRNA
  • HY-174618
    Human IL22RA2 mRNA 98%
    Human IL22RA2 mRNA encodes the human interleukin 22 receptor subunit alpha 2 (IL22RA2) protein, a member of the class II cytokine receptor family. IL22RA2 may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon.
    Human IL22RA2 mRNA
  • HY-174619
    Human IL22RA1 mRNA 98%
    Human IL22RA1 mRNA encodes the human interleukin 22 receptor subunit alpha 1 (IL22RA1) protein, a member of the class II cytokine receptor family. IL22RA1 has been shown to be a receptor for interleukin 22 (IL22).
    Human IL22RA1 mRNA
  • HY-174620
    Human IL22 mRNA 98%
    Human IL22 mRNA encodes the human interleukin 22 (IL22) protein, a member of the IL10 family of cytokines that mediate cellular inflammatory responses. IL22 functions in antimicrobial defense at mucosal surfaces and in tissue repair. It also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases.
    Human IL22 mRNA
  • HY-174621
    Human IL21R mRNA 98%
    Human IL21R mRNA encodes the human interleukin 21 receptor (IL21R) protein, a cytokine receptor for interleukin 21 (IL21). IL21R can transduce the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.
    Human IL21R mRNA
  • HY-174622
    Human IL21 mRNA 98%
    Human IL21 mRNA encodes the human interleukin 21 (IL21) protein, a member of the common-gamma chain family of cytokines. IL21 plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells.
    Human IL21 mRNA
  • HY-174623
    Human IL20RA mRNA 98%
    Human IL20RA mRNA encodes the human interleukin 20 receptor subunit alpha (IL20RA) protein, a member of the type II cytokine receptor family. IL20RA is a subunit of the receptor for interleukin 20, a cytokine that may involve in epidermal function.
    Human IL20RA mRNA
  • HY-174624
    Human IL20 mRNA 98%
    Human IL20 mRNA encodes the human interleukin 20 (IL20) protein, a proinflammatory and angiogenic cytokine that may involves in epidermal function and psoriasis.
    Human IL20 mRNA
  • HY-174625
    Human IL2 mRNA
    Human IL2 mRNA encodes the human interleukin 2 (IL2) protein, a member of the interleukin 2 (IL2) cytokine subfamily. IL2 is produced by activated CD4+ and CD8+ T lymphocytes. It is important for the proliferation of T and B lymphocytes.
    Human IL2 mRNA
  • HY-174626
    Human IL1R1 mRNA 98%
    Human IL1R1 mRNA encodes the human interleukin 1 receptor type 1 (IL1R1) protein, a cytokine receptor that belongs to the interleukin-1 receptor family. IL1R1 is an important mediator involved in many cytokine-induced immune and inflammatory responses.
    Human IL1R1 mRNA
  • HY-174627
    Human IL1B mRNA 98%
    Human IL1B mRNA encodes the human interleukin 1 beta (IL1B) protein, a member of the interleukin 1 cytokine family. IL1B is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.
    Human IL1B mRNA
  • HY-174628
    Human IL1A mRNA 98%
    Human IL1A mRNA encodes the human interleukin 1 alpha (IL1A) protein, a member of the interleukin 1 cytokine family. IL1A is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis.
    Human IL1A mRNA
  • HY-174629
    Human IL19 mRNA 98%
    Human IL19 mRNA encodes the human interleukin 19 (IL19) protein, a cytokine that belongs to the IL10 cytokine subfamily. IL19 may play some important roles in inflammatory responses.
    Human IL19 mRNA
  • HY-174630
    Human IL18R1 mRNA 98%
    Human IL18R1 mRNA encodes the human interleukin 18 receptor 1 (IL18R1) protein, a cytokine receptor that belongs to the interleukin 1 receptor family. IL18R1 is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells.
    Human IL18R1 mRNA
Cat. No. Product Name / Synonyms Application Reactivity