2. Signaling Pathways
  3. Anti-infection
  4. Bacterial

Bacterial

Bacterial

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Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14886
    Pyridindolol K2
    		Inhibitor
    Pyridindolol K2 is an alkaloid antibiotic found in Str. Sp. K93-0711. Pyridindolol K2 can inhibit the adhesion of HL-60 cells.
    Pyridindolol K2
  • HY-B0343AR
    Sarafloxacin hydrochloride (Standard)
    		Inhibitor
    Sarafloxacin (hydrochloride) (Standard) is the analytical standard of Sarafloxacin (hydrochloride). This product is intended for research and analytical applications. Sarafloxacin (hydrochloride) (A-56620 (hydrochloride)) is a quinolone antibiotic agent.
    Sarafloxacin hydrochloride (Standard)
  • HY-N7322
    Swietemahalactone
    		Inhibitor
    Swietemahalactone is a natural compound isolated from Swietenia mahagoni. Swietemahalactone exhibits antibacterial activity aganist E. coli.
    Swietemahalactone
  • HY-17359S1
    Deferasirox-13C6
    		Inhibitor
    Deferasirox-13C6 (ICL 670-13C6) is 13C labeled Deferasirox. Deferasirox (ICL 670) is an orally available iron chelator used for the management of transfusional iron overload.
    Deferasirox-<sup>13</sup>C<sub>6</sub>
  • HY-W736195
    5-Hydroxy-4-oxo-L-norvaline
    		Inhibitor
    5-Hydroxy-4-oxo-L-norvaline is an antifungal antibiotic. 5-Hydroxy-4-oxo-L-norvaline can inhibit protein biosynthesis.
    5-Hydroxy-4-oxo-L-norvaline
  • HY-119963A
    trans-β-Terpineol
    		Inhibitor
    trans-β-Terpineol is a cyclic monoterpene alcohol present in Greek propolis and the essential oil of Peganum harmala seeds, with biological activities. trans-β-Terpineol serves as a substrate for biotransformation in tobacco suspension cells, where allylic hydroxylation occurs at specific sites. trans-β-Terpineol can be isolated from the leaves of Euryops arabicus. Terpineol (HY-N7851) exhibits antioxidant and antibacterial activities, and trans-β-terpineol is the bioactive compound responsible for the antibacterial effect in Euryops arabicus.
    trans-β-Terpineol
  • HY-N13941
    Baciphelacin
    		Inhibitor
    Baciphelacin is mainly resistant to gram-positive bacteria and has the activity of inhibiting Newcastle disease virus and leukemia P-388 cells.
    Baciphelacin
  • HY-123098
    Tetrahydromethotrexate
    Tetrahydromethotrexate is a more potent folate antagonist than Methotrexate (HY-14519) in studies against certain bacteria (Streptococcus faecalis, Pediococcus erevisiae) and in animal models. Tetrahydromethotrexate is used in the research of cancer and autoimmune diseases.
    Tetrahydromethotrexate
  • HY-168995
    BAR-072
    		Inhibitor
    BAR-072 is a small-molecule inhibitor targeting TraE, with a KD of 2.7 µM. It significantly inhibits the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 shows promise as a candidate compound for blocking the spread of bacterial resistance genes and holds potential for research in infectious disease and antimicrobial resistance control.
    BAR-072
  • HY-A0253R
    Cefacetrile (Standard)
    		Inhibitor
    Cefacetrile (Standard) is the analytical standard of Cefacetrile. This product is intended for research and analytical applications. Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection.
    Cefacetrile (Standard)
  • HY-W088066A
    Trisodium phosphate (dodecahydrate), 98%
    		Inhibitor
    Trisodium phosphate dodecahydrate, 98% is an Antibacterial agent. Trisodium phosphate dodecahydrate, 98% reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate, 98% modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate, 98% is used in poultry processing.
    Trisodium phosphate (dodecahydrate), 98%
  • HY-161094
    Metallo-β-lactamase-IN-12
    		Inhibitor
    Metallo-β-lactamase-IN-12 is a dual inhibitor of metal β-lactamases (MβLs (NDM-1, IMP-1)) and serine β-lactamases (SβLs (OXA-48, KPC-2)), with IC50 values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM, respectively. Metallo-β-lactamase-IN-12 has antibacterial activity.
    Metallo-β-lactamase-IN-12
  • HY-N14616
    Reumycin
    		Inhibitor
    Reumycin is a 7-azapteridine antibiotic. Reumycin is toxic to Airy carcinoma, sarcoma-180, sarcoma-37, lymphosarcoma and other tumor cells.
    Reumycin
  • HY-179301
    GuaB-IN-2
    GuaB-IN-2 (Compound 54) is a GuaB inhibitor, with an IC50 of 0.2 nM for M. tuberculosis GuaB. GuaB-IN-2 can be used in the research of bacterial infections and tuberculosis.
    GuaB-IN-2
  • HY-B0337AR
    Sulfadimethoxine sodium (Standard)
    		Inhibitor
    Sulfadimethoxine (sodium) (Standard) is the analytical standard of Sulfadimethoxine sodium (HY-B0337A). This product is intended for research and analytical applications. Sulfadimethoxine (Sulphadimethoxine) sodium is an orally active sulfonamide antibiotic. Sulfadimethoxine sodium reduces Eimeria-related mortality, weight loss, and lesions. Sulfadimethoxine sodium can be used for the research of avian coccidiosis.
    Sulfadimethoxine sodium (Standard)
  • HY-131130A
    Neomycin C hexaacetate
    		Inhibitor
    Neomycin C hexaacetate is an impurity of Neomycin (HY-150520) and a stereoisomer of Neomycin B (HY-17624). Neomycin C hexaacetate exerts in vitro antimicrobial activity against Staphylococcus epidermidis and Staphylococcus aureus. Neomycin C hexaacetate can be used for the research of bacterial infection.
    Neomycin C hexaacetate
  • HY-173077
    PD-L1/LpxC-IN-1
    		Inhibitor
    PD-L1/LpxC-IN-1 (Conpound 12b) is the inhibitor for PD-L1 and LpxC with IC50 of 5.2 μM and 0.081 μM. PD-L1/LpxC-IN-1 inhibits the biosynthesis of bacterial lipopolysaccharide, causes the lysis and death of bacterial cells. PD-L1/LpxC-IN-1 inhibits Gram-negative bacteria, MIC for K. pneumoniae ATCC 13883, E. coli ATCC 8739, S. typhimurium ATCC 14028 and P. aeruginosa ATCC 9027 is 0.25-0.5 μg/mL. PD-L1/LpxC-IN-1 downregulates the expression of inflammatory factors IL-2 and IFN-γ, upregulates the expression of CD4+ and CD8+ cells, thereby activating the immune system and inhibiting excessive inflammatory responses. PD-L1/LpxC-IN-1 exhibits antibacterial activity in K. pneumoniae ATCC 13883 infected mouse models.
    PD-L1/LpxC-IN-1
  • HY-N14459
    Pluracidomycin C2
    		Inhibitor
    Pluracidomycin C2 is a carbapenem antibiotic. Pluracidomycin C2 has anti-Gram-positive bacteria and Gram-negative bacteria activities.
    Pluracidomycin C2
  • HY-N14155
    Epelmycin A
    		Inhibitor
    Epelmycin A has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.
    Epelmycin A
  • HY-119172R
    NSC-60339 (Standard)
    		Inhibitor
    NSC-60339 (Standard) is the analytical standard of NSC-60339. This product is intended for research and analytical applications. NSC-60339, an efflux pump inhibitor and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent.
    NSC-60339 (Standard)
Cat. No. Product Name / Synonyms Application Reactivity