2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3819):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-105020
    Derpanicate
    Derpanicate is a Nicotinic acid (HY-B0143) ester. Derpanicate has antihypercholesterolaemic and/or vasodilating effects.
    Derpanicate
  • HY-176938
    AfaPhos1
    AfaPhos1 is a new, Afatinib (HY-10261)-based EGFR PhosTAC. AfaPhos1 induces EGFR dephosphorylation at both pY1068 and pY845. AfaPhos1 induces Apoptosis. AfaPhos1 has anticancer activity against non-small cell lung cancer.
    AfaPhos1
  • HY-133160
    Valproic acid hydroxamate
    Valproic acid hydroxamate (VPA-HA) has shown anticonvulsant activity in a mouse neural tube defect model, without any teratogenic effects.
    Valproic acid hydroxamate
  • HY-131390
    S-Ethylglutathione
    S-Ethylglutathione is a biochemical.
    S-Ethylglutathione
  • HY-N17157
    1β-Hydroxy-8α-methoxyeremophila-7(11),9-dien-12,8β-olide
    1β-Hydroxy-8α-methoxyeremophila-7(11),9-dien-12,8β-olide is a natural sesquiterpene.
    1β-Hydroxy-8α-methoxyeremophila-7(11),9-dien-12,8β-olide
  • HY-N13805
    1-Oxohederagenin
    1-Oxohederagenin is a natural triterpene.
    1-Oxohederagenin
  • HY-N17010
    Quassidine B
    Quassidine B (Dihydropicrasidine A) is a natural alkaloid.
    Quassidine B
  • HY-P992482
    VIR-2482
    VIR-2482 is a monoclonal antibody targeting influenza A hemagglutinin (HA). VIR-2482 is generated by introducing LS mutations (M428L/N434S) into the Fc region of MEDI8852 (HY-P991446). VIR-2482 binds to the conserved HA stem epitope across all 18 influenza A HA subtypes, neutralizes a broad spectrum of H1N1 and H3N2 strains, binds to FcγRIIIa, FcγRIIa and C1q, and induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. VIR-2482 reduces morbidity and mortality caused by seasonal influenza A strains and provides prophylactic protection in mice. VIR-2482 can be used in research related to influenza A disease.
    VIR-2482
  • HY-N17083
    Lucidafuranocoumarin B
    Lucidafuranocoumarin B is a natural coumarin.
    Lucidafuranocoumarin B
  • HY-N7301
    Glabratine
    Glabratine is a natural alkaloid.
    Glabratine
  • HY-N16936
    (Z)-Pinosylvin monomethyl ether
    (Z)-Pinosylvin monomethyl ether is a natural phenolic compound.
    (Z)-Pinosylvin monomethyl ether
  • HY-N13761
    Physaminimin N
    Physaminimin N is a natural steroid.
    Physaminimin N
  • HY-N9864
    Mahanimbinol
    Mahanimbinol is a natural alkaloid.
    Mahanimbinol
  • HY-N17104
    Bisandrographolide G
    Bisandrographolide G is a natural diterpene.
    Bisandrographolide G
  • HY-N16712
    Powelline
    Powelline is a natural alkaloid.
    Powelline
  • HY-126071
    (-)-Mitorubrinic acid
    (-)-Mitorubrinic acid (Mitorubrinic acid) is a polyketide. (-)-Mitorubrinic acid is synthesis by two non-reducing polyketide synthase (PKS) genes (pks12 and pks11) in a sequential manner. (-)-Mitorubrinic is a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages.
    (-)-Mitorubrinic acid
  • HY-158595
    15(R),19(R)-Hydroxy prostaglandin F2α
    15(R),19(R)-Hydroxy prostaglandin F2α (15(R),19(R)-Hydroxy PGF2α) is an analog of 19(R)-Hydroxy-prostaglandin F2α. 19(R)-Hydroxy-prostaglandin F2α (HY-N7857) is an ω-1 hydroxylase metabolite of PGF2α found in human semen.
    15(R),19(R)-Hydroxy prostaglandin F2α
  • HY-181124
    Idebenone-SS-20
    Idebenone-SS-20 (Idebenone-2S-FrFK-NH2) is a Idebenone (HY-N0303) derivative conjugated to the mitochondria-targeting peptide SS-20. Idebenone-SS-20 shows neuroprotective and anti-inflammatory effects. Idebenone-SS-20 can preserve mitochondrial membrane potential, enhance ATP production, reduce ROS accumulation, maintain mitochondrial morphology and elevate NAD+/NADH ratio. Idebenone-SS-20 confers robust neuroprotection in a murine model of transient middle cerebral artery occlusion. Idebenone-SS-20 can be used for the research of cerebral.
    Idebenone-SS-20
  • HY-120700
    L-682,679
    L-682,679 is an active compound.
    L-682,679
  • HY-169479
    Betulinic glycine amide
    Betulinic glycine amide (compound 5a) is a pentacyclic triterpenoid and derivative of Betulinic acid (HY-10529). Betulinic glycine amide has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity.
    Betulinic glycine amide