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Cat. No.: HY-169479

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Betulinic glycine amide

Name: Betulinic glycine amide
Brand: MedChemExpress
SKU: HY-169479
Price: 122.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Betulinic glycine amide (compound 5a) is a pentacyclic triterpenoid and derivative of Betulinic acid (HY-10529). Betulinic glycine amide has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity.

For research use only. We do not sell to patients.

CAS No.: 174740-40-0
Formula: C₃₂H₅₁NO₄
Molecular Weight:513.75

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Betulinic glycine amide Chemical Structure

CAS No.: 174740-40-0

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Biological Activity
- Description
- Cellular Effect
Chemical Information
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	>10 μM Compound: 33	Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assay Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assay	[PMID: 19911773]
KB	ED₅₀	>20 μg/mL Compound: 16	In vitro cytotoxicity (antitumor activity) against human epidermoid carcinoma of mouth cell line (KB) In vitro cytotoxicity (antitumor activity) against human epidermoid carcinoma of mouth cell line (KB)	[PMID: 10328313]
SK-MEL-2	ED₅₀	4.2 μg/mL Compound: 16	In vitro cytotoxicity (antitumor activity) against human melanoma (MEL-2) cell lines In vitro cytotoxicity (antitumor activity) against human melanoma (MEL-2) cell lines	[PMID: 10328313]

Chemical Information

CAS No. 174740-40-0
Molecular Weight 513.75
Formula C₃₂H₅₁NO₄
SMILES

OC(CNC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)([C@H](CC5)O)C)([H])CC4)C)([H])CC3)C)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. F Soler, et al. Betulinic Acid Derivatives: A New Class of Specific Inhibitors of Human Immunodeficiency Virus Type 1 Entry. J Med Chem. 1996 Mar 1;39(5):1069-83. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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