2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Cytoskeleton
  4. Microtubule/Tubulin
  5. α-Tubulin Isoform
  6. α-Tubulin Activator

α-Tubulin Activator

α-Tubulin Activator (1):

Cat. No. Product Name Effect Purity
  • HY-182904
    GV-001
    		Activator
    GV-001 is a selective and orally active HDAC6 inhibitor with an IC50 of 1.18 nM against HDAC6. GV-001 selectively enhances α-tubulin acetylation, reduces sIL-6 and Collagen I levels, suppresses renal cyst growth, and upregulates PC1 expression. GV-001 can be used for the study of autosomal dominant polycystic kidney disease (ADPKD).