2. Signaling Pathways
  3. GPCR/G Protein
  4. Prostaglandin Receptor
  5. FP Isoform
  6. FP Inhibitor

FP Inhibitor

FP Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-100441
    Treprostinil
    		Inhibitor 99.98%
    Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
  • HY-118014
    CAY10535
    		Inhibitor
    CAY10535 is a FP and TP receptor inhibitor and can be used for research of cardiovascular diseases.
  • HY-101438A
    Darbufelone mesylate
    		Inhibitor 98.45%
    Darbufelone mesylate (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone potently inhibits PGHS-2 (IC50 = 0.19 μM) but is much less potent with PGHS-1 (IC50= 20 μM).
  • HY-P4160
    PDC31
    		Inhibitor 99.76%
    PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca2+-dependent large-conductance K+-channel in human myometrial cells.
  • HY-113756A
    Latanoprost acid
    		Inhibitor 99.62%
    Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes.