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Cat. No.: HY-118014

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CAY10535

CAY10535 is a FP and TP receptor inhibitor and can be used for research of cardiovascular diseases.

For research use only. We do not sell to patients.

CAS No.: 945716-28-9
Formula: C₁₈H₂₁N₃O₇S
Molecular Weight:423.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

CAY10535 Chemical Structure

CAS No.: 945716-28-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CAY10535 is a FP and TP receptor inhibitor and can be used for research of cardiovascular diseases^[1].

IC₅₀ & Target

TP Receptor

FP Receptor

All Prostaglandin Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	1970 nM Compound: 9ag	Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization	[PMID: 17630727]
HEK293	IC₅₀	99 nM Compound: 9ag	Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobilization	[PMID: 17630727]

In Vitro

CAY10535 (10 μM) significantly inhibits PGF_2α (1 μM) and/or capsaicin (2 μM) induced coronary rings contractions^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 945716-28-9
Molecular Weight 423.44
Formula C₁₈H₂₁N₃O₇S
SMILES

O=S(C1=CC([N+]([O-])=O)=CC=C1OC2=CC=CC(OC)=C2)(NC(NC(C)(C)C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. S Christopher Hiett, et al. Mechanisms underlying capsaicin effects in canine coronary artery: implications for coronary spasm. Cardiovasc Res. 2014 Sep 1;103(4):607-18. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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CAY10535

High-Throughput Bioactive Compound Library

All Prostaglandin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CAY10535 Related Classifications

HY-118014 Related Classifications