1. Signaling Pathways
  2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. TXA2/TP Isoform

TXA2/TP

 

TXA2/TP Related Products (26):

Cat. No. Product Name Effect Purity
  • HY-50901
    ONO-AE3-208
    Antagonist 98.65%
    ONO-AE3-208 is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM.
  • HY-50175
    Laropiprant
    Antagonist 99.73%
    Laropiprant is a potent and selective DP receptor antagonist with Ki values of 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively.
  • HY-100441
    Treprostinil
    Inhibitor 99.98%
    Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
  • HY-B0428
    Ozagrel
    Inhibitor 99.96%
    Ozagrel (OKY-046)is an anti-asthmatic agent and a thromboxane A2 (TXA2) synthase inhibitor.
  • HY-111271
    L 888607
    Agonist 99.95%
    L 888607 is a potent, selective, stable and orally active CRTH2 agonist.
  • HY-108563A
    SC 51089 free base
    Antagonist 98.64%
    SC 51089 free base is a selective antagonist of prostaglandin E2 EP1 receptor, with Kis of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively.
  • HY-118044
    I-SAP
    Antagonist
    I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist.
  • HY-113350
    Thromboxane A2
    Activator
    Thromboxane A2 (TXA2) is a prostanoid mediator produced by the metabolism of Arachidonic acid (HY-109590) through the cyclooxygenase pathway.
  • HY-N0607
    Ginsenoside Ro
    Inhibitor 99.21%
    Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) exhibits a Ca2+-antagonistic antiplatelet effect with an IC50 of 155  μM.
  • HY-16504
    Treprostinil sodium
    Agonist ≥98.0%
    Treprostinil (UT-15) sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
  • HY-129851
    NTP42
    Antagonist 98.02%
    NTP42 is a thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46619.
  • HY-B0745
    Ramatroban
    Antagonist 99.10%
    Ramatroban is a selective thromboxane A2 (TxA2, IC50=14 nM) antagonist, which also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding.
  • HY-15853
    MK-7246
    Antagonist 98.95%
    MK-7246 is a potent and selective CRTH2 antagonist with a Ki of 2.5±0.5 nM.
  • HY-B0428B
    Ozagrel hydrochloride
    Inhibitor 99.68%
    Ozagrel hydrochloride (OKY-046 hydrochloride) is a thromboxane A2 (TXA2) synthase inhibitor.
  • HY-111271A
    L 888607 Racemate
    Antagonist 99.83%
    L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.
  • HY-U00253
    KP496
    Antagonist
    KP496 is a selective, dual antagonist for Leukotriene D4 receptor and Thromboxane A2 receptor.
  • HY-B0428A
    Ozagrel sodium
    Inhibitor 99.98%
    Ozagrel sodium (OKY-046 sodium) is a thromboxane A2 (TXA2) synthase inhibitor.
  • HY-108563
    SC 51089
    Antagonist
    SC 51089 is a selective antagonist of prostaglandin E2 EP1 receptor, with Kis of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively.
  • HY-50175A
    Laropiprant sodium
    Antagonist
    Laropiprant sodium is a potent and selective DP receptor antagonist with Ki values of 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively.
  • HY-121018
    Daltroban
    Antagonist
    Daltroban (BM-13505) is a selective and specific thromboxane A2 (TXA2) receptor antagonist.