1. Signaling Pathways
  2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. TXA2/TP Isoform
  5. TXA2/TP Antagonist

TXA2/TP Antagonist

TXA2/TP Antagonists (14):

Cat. No. Product Name Effect Purity
  • HY-50901
    ONO-AE3-208
    Antagonist 98.65%
    ONO-AE3-208 is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM.
  • HY-50175
    Laropiprant
    Antagonist 99.73%
    Laropiprant is a potent and selective DP receptor antagonist with Ki values of 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively.
  • HY-108563A
    SC 51089 free base
    Antagonist
    SC 51089 free base is a selective antagonist of prostaglandin E2 EP1 receptor, with Kis of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively.
  • HY-B0745
    Ramatroban
    Antagonist 99.10%
    Ramatroban is a selective thromboxane A2 (TxA2, IC50=14 nM) antagonist, which also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding.
  • HY-129851
    NTP42
    Antagonist 98.02%
    NTP42 is a thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609.
  • HY-111271A
    L 888607 Racemate
    Antagonist 99.83%
    L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.
  • HY-15853
    MK-7246
    Antagonist 98.95%
    MK-7246 is a potent and selective CRTH2 antagonist with a Ki of 2.5±0.5 nM.
  • HY-U00253
    KP496
    Antagonist
    KP496 is a selective, dual antagonist for Leukotriene D4 receptor and Thromboxane A2 receptor.
  • HY-108563
    SC 51089
    Antagonist
    SC 51089 is a selective antagonist of prostaglandin E2 EP1 receptor, with Kis of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively.
  • HY-50175A
    Laropiprant sodium
    Antagonist
    Laropiprant sodium is a potent and selective DP receptor antagonist with Ki values of 0.57 nM and 2.95 nM for DP receptor and TP Receptor, respectively.
  • HY-121018
    Daltroban
    Antagonist
    Daltroban (BM-13505) is a selective and specific thromboxane A2 (TXA2) receptor antagonist.
  • HY-101700
    LCB-2853
    Antagonist
    LCB-2853 is an antagonist of thromboxane A2 (TXA2) receptor, with antiplatelet and antithrombotic activities.
  • HY-U00072
    RS-601
    Antagonist
    RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities.
  • HY-U00355
    YM158 free base
    Antagonist
    YM158 free base is a potent and selective LTD4 and TXA2 receptor antagonist with pA2 values of about 8.87 and 8.81, respectively.