I-SAP
I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC).
For research use only. We do not sell to patients.
- CAS No.: 133538-58-6
- Formula: C22H30INO4S
- Molecular Weight:531.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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TXA2 Receptor |
Chemical Information
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CAS No. 133538-58-6
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Molecular Weight 531.45
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Formula C22H30INO4S
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SMILES
OC(CCC/C=C\C[C@H]1[C@@](C[C@]2([H])C[C@@H]1N[S](=O)(C(C=C3)=CC=C3I)=O)([H])C2(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Saussy DL Jr, et al. Binding of a novel radioiodinated thromboxane A2/prostaglandin H2 antagonist to guinea pig lung membranes. Eicosanoids. 1992;5(1):1-4. [Content Brief]
[2]. Schrör K, et al. Inhibition of ligand binding to thromboxane A2/prostaglandin H2 receptors by diethylpyrocarbonate. Protection by receptor ligands and reversal by hydroxylamine. Biochem Pharmacol. 1995 Mar 30;49(7):921-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)