2. Signaling Pathways
  3. GPCR/G Protein
  4. Prostaglandin Receptor
  5. EP Isoform

EP

 

EP Related Products (61):

Cat. No. Product Name Effect Purity
  • HY-18966
    PF-04418948
    		Antagonist 99.56%
    PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM.
  • HY-50901
    ONO-AE3-208
    		Antagonist 98.65%
    ONO-AE3-208 is a selective and orally active EP4 receptor antagonist with a Ki of 1.3 nM.
  • HY-16781
    Grapiprant
    		Antagonist 99.20%
    Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2).
  • HY-106420
    16,16-Dimethyl prostaglandin E2
    		Modulator ≥98.0%
    16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator.
  • HY-16963
    GW627368
    		Antagonist 99.81%
    GW627368 (GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor with additional human TP receptor affinity, with pKi values of 7.0 and 6.8 for human prostanoid EP4 and TP receptors respectively.
  • HY-108563A
    SC 51089 free base
    		Antagonist 98.64%
    SC 51089 free base is a selective antagonist of prostaglandin E2 EP1 receptor, with Kis of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively.
  • HY-106054
    Nocloprost
    		Agonist
    Nocloprost, a prostaglandin E2 (PGE2) analog, is an orally active EP1- and EP3-receptor agonist.
  • HY-153129
    EP2 receptor antagonist-2
    		Antagonist
    EP2 receptor antagonist-2 (CID891729) is an antagonist of EP2 receptor.
  • HY-15274
    L-798106
    		Antagonist 99.85%
    L-798106 is potent and highly selective prostanoid EP3 receptor antagonist (Ki=0.3 nM), it also has  micromolar activities at the EP4, EP1 and EP2 receptors with Ki values of 916 nM, >5000 nM and >5000 nM, respectively.
  • HY-10418
    AH 6809
    		Antagonist 99.47%
    AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively.
  • HY-100441
    Treprostinil
    		Inhibitor 99.98%
    Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
  • HY-10797
    CJ-42794
    		Antagonist 98.84%
    CJ-42794 (CJ-042794) is a potent, orally active, selective prostaglandin E receptor 4 (EP4) antagonist with an IC50 value of 10 nM, which is 200-fold more selective than EP1, EP2 and EP3.
  • HY-N0314
    Pectolinarin
    		Inhibitor 99.89%
    Pectolinarin possesses anti-inflammatory activity.
  • HY-10413
    MK-2894
    		Antagonist 99.31%
    MK-2894 is a potent, selective, orally active and high affinity (Ki=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC50=2.5 nM).
  • HY-10835
    DG-041
    		Antagonist 99.15%
    DG-041 is a potent, high affinity and selective EP3 receptor antagonist with IC50s of 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively.
  • HY-10794
    MF498
    		Antagonist 98.90%
    MF498 is a selective and orally active E prostanoid Receptor 4 (EP4) antagonist with a Ki value of 0.7 nM.
  • HY-111271
    L 888607
    		Agonist 99.95%
    L 888607 is a potent, selective, stable and orally active CRTH2 agonist.
  • HY-17642
    Omidenepag
    		Agonist 99.78%
    Omidenepag,a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM.
  • HY-14839
    Evatanepag
    		Agonist 99.48%
    Evatanepag (CP-533536) is a non-prostanoid, potent and selective EP2 receptor agonist.
  • HY-18971
    TG4-155
    		Antagonist 99.69%
    TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM.