1. GPCR/G Protein
  2. Prostaglandin Receptor

PF-04418948 

Cat. No.: HY-18966 Purity: 99.60%
Handling Instructions

PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM.

For research use only. We do not sell to patients.

PF-04418948 Chemical Structure

PF-04418948 Chemical Structure

CAS No. : 1078166-57-0

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 77 In-stock
Estimated Time of Arrival: December 31
5 mg USD 70 In-stock
Estimated Time of Arrival: December 31
10 mg USD 110 In-stock
Estimated Time of Arrival: December 31
50 mg USD 440 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

    PF-04418948 purchased from MCE. Usage Cited in: J Virol. 2018 Aug 1. pii: JVI.01018-18.

    A549 cells are added with an EP2 or an EP4 inhibitor. After 48 h, cells are subjected to WB with an anti-Axl antibody.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References

    Description

    PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM.

    Clinical Trial
    Solvent & Solubility
    In Vitro: 

    10 mM in DMSO

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.4425 mL 12.2127 mL 24.4254 mL
    5 mM 0.4885 mL 2.4425 mL 4.8851 mL
    10 mM 0.2443 mL 1.2213 mL 2.4425 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
    Molecular Weight

    409.41

    Formula

    C₂₃H₂₀FNO₅

    CAS No.

    1078166-57-0

    SMILES

    O=C(C1(COC2=CC=C3C=C(OC)C=CC3=C2)CN(C(C4=CC=C(F)C=C4)=O)C1)O

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Shipping

    Room temperature in continental US; may vary elsewhere

    Purity: 99.60%

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
    C1   V1   C2   V2

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    Product Name:
    PF-04418948
    Cat. No.:
    HY-18966
    Quantity:

    PF-04418948

    Cat. No.: HY-18966