2287259-07-6
2287259-07-6
Chemical Structure
EP4 receptor antagonist 1
- CAS No.: 2287259-07-6
- Formula:C23H21F3N4O3
- Molecular Weight:458.43
IUPAC Name: (S,E)-4-(1-(4-(prop-1-en-1-yl)-1-(4-(trifluoromethyl)benzyl)-1H-1,2,3-triazole-5-carboxamido)ethyl)benzoic acid
InChIKey: ZTWUZRMXAVDXJV-XGACYXMMSA-N
SMILES: O=C(O)C1=CC=C([C@@H](NC(C2=C(/C=C/C)N=NN2CC3=CC=C(C(F)(F)F)C=C3)=O)C)C=C1
Biological Activity: EP4 receptor antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy. EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC50s of 6.1 nM and 16.2 nM, respectively. IC50s >10 μM for human EP1, EP2,and EP3 receptors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EP4 receptor antagonist 1 | 99.94% | EP4 receptor antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy. EP4 receptor antagonist 1 inhibits human and mouse EP4 receptor with IC50s of 6.1 nM and 16.2 nM, respectively. IC50s >10 μM for human EP1, EP2,and EP3 receptors. | ||||||||||||||||||||
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