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  3. L 888607

L 888607 

Cat. No.: HY-111271 Purity: 99.88%
Handling Instructions

L 888607 is a potent, and selective CRTH2 (also known as DP2) agonist with a Ki of 0.8 nM.

For research use only. We do not sell to patients.

L 888607 Chemical Structure

L 888607 Chemical Structure

CAS No. : 860033-06-3

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 352 In-stock
Estimated Time of Arrival: December 31
5 mg USD 320 In-stock
Estimated Time of Arrival: December 31
10 mg USD 520 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1700 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2400 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L 888607:

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Description

L 888607 is a potent, and selective CRTH2 (also known as DP2) agonist with a Ki of 0.8 nM.

IC50 & Target[1]

CRTH2/DP2 Receptor

0.8 nM (Ki)

DP/DP1 Receptor

2331 nM (Ki)

TP Receptor

283 nM (Ki)

EP2 Receptor

8748 nM (Ki)

EP3-III Receptor

1260 nM (Ki)

EP4 Receptor

4634 nM (Ki)

FP Receptor

10018 nM (Ki)

IP Receptor

14434 nM (Ki)

Molecular Weight

375.84

Formula

C₁₉H₁₅ClFNO₂S

CAS No.

860033-06-3

SMILES

O=C(O)C[[email protected]@H]1CCN2C1=C(SC3=CC=C(Cl)C=C3)C4=C2C=C(F)C=C4

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 150 mg/mL (399.11 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6607 mL 13.3035 mL 26.6071 mL
5 mM 0.5321 mL 2.6607 mL 5.3214 mL
10 mM 0.2661 mL 1.3304 mL 2.6607 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.65 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.65 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Animal Administration

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
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Product Name:
L 888607
Cat. No.:
HY-111271
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