1. GPCR/G Protein
  2. Prostaglandin Receptor

Terutroban (Synonyms: S-18886)

Cat. No.: HY-16991 Purity: 99.59%
Data Sheet SDS Handling Instructions

Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.

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Terutroban Chemical Structure

Terutroban Chemical Structure

CAS No. : 165538-40-9

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10 mM * 1 mL in DMSO $72 In-stock
10 mg $65 In-stock
50 mg $280 In-stock
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Description

Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist. IC50 value: Target: TP receptor in vivo: Terutroban is a selective antagonist of the thromboxane/prostaglandin endoperoxide receptor, in preventing retinal ischaemia in a model of diabetes in rats. Terutroban significantly protect retinal vascularity from ischaemia in experimental diabetes, and this result could be attributed not only to its antiplatelet/antithrombotic activities but also to its vascular properties.[1] Terutroban has antiplatelet properties. In addition, Terutroban has shown to improve flow-mediated dilatation of the brachial artery after a single administration in patients with coronary artery disease. [2] Terutroban is a potent antithrombotic agent and also possesses antiatherosclerotic and antivasoconstrictor properties. [3]

References
Molecular Weight

407.91

Formula

C₂₀H₂₂ClNO₄S

CAS No.

165538-40-9

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 22 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
Terutroban
Cat. No.:
HY-16991
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