1. GPCR/G Protein
  2. Prostaglandin Receptor

Terutroban (Synonyms: S-18886)

Cat. No.: HY-16991 Purity: 99.59%
Handling Instructions

Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.

For research use only. We do not sell to patients.

Terutroban Chemical Structure

Terutroban Chemical Structure

CAS No. : 165538-40-9

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 86 In-stock
Estimated Time of Arrival: December 31
10 mg USD 78 In-stock
Estimated Time of Arrival: December 31
50 mg USD 336 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References


Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist. IC50 value: Target: TP receptor in vivo: Terutroban is a selective antagonist of the thromboxane/prostaglandin endoperoxide receptor, in preventing retinal ischaemia in a model of diabetes in rats. Terutroban significantly protect retinal vascularity from ischaemia in experimental diabetes, and this result could be attributed not only to its antiplatelet/antithrombotic activities but also to its vascular properties.[1] Terutroban has antiplatelet properties. In addition, Terutroban has shown to improve flow-mediated dilatation of the brachial artery after a single administration in patients with coronary artery disease. [2] Terutroban is a potent antithrombotic agent and also possesses antiatherosclerotic and antivasoconstrictor properties. [3]

Solvent & Solubility
In Vitro: 

DMSO : ≥ 22 mg/mL (53.93 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4515 mL 12.2576 mL 24.5152 mL
5 mM 0.4903 mL 2.4515 mL 4.9030 mL
10 mM 0.2452 mL 1.2258 mL 2.4515 mL
*Please refer to the solubility information to select the appropriate solvent.
Molecular Weight







O=C(O)CCC1=C2CC[[email protected]@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C

Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Cat. No.: HY-16991