2. Signaling Pathways
  3. GPCR/G Protein
  4. Prostaglandin Receptor
  5. TXA2/TP Isoform
  6. TXA2/TP Inhibitor

TXA2/TP Inhibitor

TXA2/TP Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-100441
    Treprostinil
    		Inhibitor 99.98%
    Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
  • HY-118014
    CAY10535
    		Inhibitor
    CAY10535 is a FP and TP receptor inhibitor and can be used for research of cardiovascular diseases.
  • HY-124150
    BM567
    		Inhibitor
    BM567 is a sulfonylurea compound (compound 1), which exhibits antithrombogenic efficacy as thromboxane A2 receptor (TXR) antagonists and thromboxane A2 synthase (TXS) inhibitors, with IC50s of 1.1 and 12 nM, respectively.
  • HY-B0428
    Ozagrel
    		Inhibitor 99.74%
    Ozagrel (OKY-046)is an anti-asthmatic agent and a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM.
  • HY-N0607
    Ginsenoside Ro
    		Inhibitor 98.69%
    Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) exhibits a Ca2+-antagonistic antiplatelet effect with an IC50 of 155  μM. Ginsenoside Ro reduces the production of TXA2 more than it reduces the activities of COX-1 and TXAS.
  • HY-B0428A
    Ozagrel sodium
    		Inhibitor 99.98%
    Ozagrel sodium (OKY-046 sodium) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel sodium is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM.
  • HY-101606
    Etersalate
    		Inhibitor
    Etersalate inhibits platelet function and decreases thromboxane A2 (TXA2) levels.