1. GPCR/G Protein
  2. Prostaglandin Receptor
  3. Ozagrel sodium

Ozagrel sodium (Synonyms: OKY-046 sodium)

Cat. No.: HY-B0428A Purity: 99.91%
Handling Instructions

Ozagrel sodium (OKY-046 sodium) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel sodium is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM.

For research use only. We do not sell to patients.

Ozagrel sodium Chemical Structure

Ozagrel sodium Chemical Structure

CAS No. : 189224-26-8

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
50 mg USD 145 In-stock
Estimated Time of Arrival: December 31
100 mg USD 220 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Ozagrel sodium (OKY-046 sodium) is a thromboxane A2 (TXA2) synthase inhibitor. Ozagrel sodium is an antiplatelet agent, which selectively inhibits human platelet aggregation with an IC50 of 53.12 μM[1].

IC50 & Target[1]

TXA2

 

Clinical Trial
Molecular Weight

250.23

Formula

C₁₃H₁₁N₂NaO₂

CAS No.

189224-26-8

SMILES

O=C(O[Na])/C=C/C1=CC=C(CN2C=CN=C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (199.82 mM; Need ultrasonic)

DMSO : 6.25 mg/mL (24.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9963 mL 19.9816 mL 39.9632 mL
5 mM 0.7993 mL 3.9963 mL 7.9926 mL
10 mM 0.3996 mL 1.9982 mL 3.9963 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.62 mg/mL (2.48 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.62 mg/mL (2.48 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

Keywords:

OzagrelOKY-046OKY046OKY 046Prostaglandin Receptorthromboxane A2TXA2antiplateletplateletaggregationInhibitorinhibitorinhibit

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Product Name:
Ozagrel sodium
Cat. No.:
HY-B0428A
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