2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
    Neuronal Signaling
  4. TRP Channel
  5. TRPA Isoform

TRPA

 

TRPA Related Products (8):

Cat. No. Product Name Effect Purity
  • HY-107436
    LE135
    		Activator 99.03%
    LE135 is a potent RAR antagonist that binds selectively to RARα (Ki of 1.4 μM) and RARβ (Ki of 220 nM), and has a higher affinity to RARβ.
  • HY-107535
    AS1269574
    		Activator 98.76%
    AS1269574 is a potent, orally available GPR119 agonist, with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119.
  • HY-W014421
    AP-18
    		Inhibitor 99.80%
    AP-18, a potent and selective TRPA1 inhibitor, blocks activation of TRPA1 by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively.
  • HY-15065
    Chembridge-5861528
    		Antagonist 99.27%
    Chembridge-5861528 (TCS 5861528) is a potent TRPA1 channel antagonist that antagonizes similarly allyl isothiocyanate- and 4-HNE-evoked TRPA1 responses, with IC50 values of 14.3 μM and 18.7 μM, respectively.
  • HY-120689
    PF-04745637
    		Antagonist 98.65%
    PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM for human TRPA1.
  • HY-N7965
    Methyl kakuol
    		Agonist
    Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM.
  • HY-104061
    AMG8788
    		Antagonist
    AMG8788 is a potent, selective, orally active antagonist of TRPM8 with an IC50 of 63.2 nM.
  • HY-104062
    AMG9678
    		Antagonist
    AMG9678 is a potent, selective, orally active antagonist of TRPM8 with an IC50 of 31.2 nM.