2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3818):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17161
    (E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde
    (E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde is a natural phenolic compound.
    (E)-5-Hydroxy-6-isoprenyl-2-(pent-1-en-1-yl)benzofuran-4-carbaldehyde
  • HY-W749329
    (5β)-3,12-Dioxocholan-24-oic acid
    (5β)-3,12-Dioxocholan-24-oic acid is a natural product that can be found in animal bile.
    (5β)-3,12-Dioxocholan-24-oic acid
  • HY-106353A
    epi-Smilagenin
    epi-Smilagenin is a 5β-spirostan-3α-ol and steroidal sapogenin. epi-Smilagenin can be found in the rumen content of sheep intoxicated by Brachiaria decumbens.
    epi-Smilagenin
  • HY-N17313
    7-Demethoxylophorine
    7-Demethoxylophorine is a natural product that can be found in mistletoe.
    7-Demethoxylophorine
  • HY-N9307
    8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione
    8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione is a natural diterpene.
    8-Acetoxy-15,16-epoxy-8,9-secolabda-13(16),14-diene-7,9-dione
  • HY-165030
    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is an active compound.
    1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
  • HY-N17545
    2′,3′-O-Diacetyl-3-O-α-L-arabinopyranosyl-23-hydroxyolea-12-en-28-oic acid
    2′,3′-O-Diacetyl-3-O-α-L-arabinopyranosyl-23-hydroxyolea-12-en-28-oic acid is a natural product that can be found in hedera nepalensis?var.?sinensis?(tobl.) rehd.
    2′,3′-O-Diacetyl-3-O-α-L-arabinopyranosyl-23-hydroxyolea-12-en-28-oic acid
  • HY-N18350
    26-Degluco-torvoside H
    26-Degluco-torvoside H (Compound 4) is a Furostanol glycoside derivative. 26-Degluco-torvoside H forms via hydrolysis of Torvoside H by β-glucosidase from Solanum torvum leaves.
    26-Degluco-torvoside H
  • HY-16778
    Etiguanfacine
    Etiguanfacine is a derivative of Guanfacine (HY-17416A). Etiguanfacine can be used for research to reduce the gastrointestinal side effects of Guanfacine.
    Etiguanfacine
  • HY-N16869
    Plantagiolide B
    Plantagiolide B is a natural steroid.
    Plantagiolide B
  • HY-N16538
    4-(Acetoxymethyl)phenyl glucoside
    4-(Acetoxymethyl)phenyl glucoside is a type of gastrodin derivative that can cross the blood-brain barrier. 4-(Acetoxymethyl)phenyl glucoside exhibits sedative, anticonvulsant and analgesic effects in mouse models. 4-(Acetoxymethyl)phenyl glucoside can be used for research on senile cardiovascular and cerebrovascular diseases as well as brain nerve disorders.
    4-(Acetoxymethyl)phenyl glucoside
  • HY-W674261
    WAY-620521
    WAY-620521 is an active molecule.
    WAY-620521
  • HY-119012
    L 681217
    L 681217 is an active compound.
    L 681217
  • HY-122040
    5-Chloro hydrochlorothiazide
    5-Chloro hydrochlorothiazide is a derivative of hydrochlorothiazide (HY-B0252), and has diuretic action.
    5-Chloro hydrochlorothiazide
  • HY-178247
    4-Demethoxydoxorubicinone
    4-Demethoxydoxorubicinone is a derivative of Doxorubicin (HY-15142A). 4-Demethoxydoxorubicinone can be used for the research of cancer.
    4-Demethoxydoxorubicinone
  • HY-118854
    Fepradinol
    Fepradinol is an active compound.
    Fepradinol
  • HY-106401
    Penclomedine
    Penclomedine (NSC 338720), a synthetic alpha-picoline derivative, is an orally active antitumor agent. Penclomedine has a strong inhibitory effect on breast cancer cells, such as CD8F1 and MX-1 cells.
    Penclomedine
  • HY-W747567
    Leukotriene E4 methyl ester
    Leukotriene E4 methyl ester is a methyl ester of Leukotriene E4 (HY-113465). Leukotriene E4 methyl ester can be used for the research of inflammatory diseases.
    Leukotriene E4 methyl ester
  • HY-W779743
    NE58043
    NE58043 (Compound 21) is a nitrogen-containing bisphosphonate compound. NE58043 has no significant inhibitory activity against Entamoeba histolytica and Plasmodium falciparum with IC50 > 200 μM. NE58043 shows a LD50 of 171 μM for human nasopharyngeal carcinoma KB cells. NE58043 can be used for the research of cancer and infection, such as nasopharyngeal carcinoma.
    NE58043
  • HY-106185
    BMS-188797
    BMS-188797 is a novel Taxane analog. BMS-188797 enhances the efficacy of radiotherapy against lung cancer.
    BMS-188797