2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3819):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-106185
    BMS-188797
    BMS-188797 is a novel Taxane analog. BMS-188797 enhances the efficacy of radiotherapy against lung cancer.
    BMS-188797
  • HY-N18254
    Hokbusine A
    Hokbusine A is a diterpenic alkaloid and C19 norditerpenoid (aconitine-type) alkaloid that can be found in the roots of Aconitum napellus L. (Swiss variety) and Aconitum jaluense.Hokbusine A exhibits low acute toxicity in ddY mice via intraperitoneal administration, with an LD50 value greater than 1 mg/kg.
    Hokbusine A
  • HY-N13791
    Platachromone B
    Platachromone B is a natural phenolic compound.
    Platachromone B
  • HY-148604
    Imuracetam
    Imuracetam is a racetam compound. Racetam compounds have good cognitive-enhancing effects.
    Imuracetam
  • HY-N19796
    Diaporol I
    Diaporol I is a pimarane-type sesquiterpene that can be isolated from the mangrove-derived endophytic fungus Diaporthe sp.
    Diaporol I
  • HY-121247
    Bromotetrandrine
    Bromotetrandrine is a potent inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). Bromotetrandrine shows significant MDR reversal activity in vitro and in vivo, which may be related to the inhibition of P-gp overexpression and the increase in intracellular accumulation of anticancer agents. Bromotetrandrine is a brominated derivative of tetrandrine, which is promising for MDR modulator for tumor assessment.
    Bromotetrandrine
  • HY-N9778
    Phoyunbene B
    Phoyunbene B is a similar substance to Resveratrol (HY-16561). Phoyunbene B exhibits stronger growth inhibitory activity against human liver cancer cells HepG2 compared to Resveratrol. Phoyunbene B induces G2/M phase cell cycle arrest and apoptosis. Phoyunbene B increases Bax/Bcl-2 and activates Caspase-3. Phoyunbene B inhibits the invasion and migration of cancer cells. Phoyunbene B can be used for research on liver cancer.
    Phoyunbene B
  • HY-172079
    3-CEC hydrochloride
    3-CEC hydrochloride is a drug derivative.
    3-CEC hydrochloride
  • HY-N7997
    Schindilactone E
    Schindilactone E is a natural product that can be found in Schisandra chinensis?(Turcz.) Baill..
    Schindilactone E
  • HY-N17538
    22α-Hydroxyoleanolic acid
    22α-Hydroxyoleanolic acid (compound 11) is a triterpenoid found in the aerial parts of Schefflera kwangsiensis.
    22α-Hydroxyoleanolic acid
  • HY-170801
    Anticonvulsant agent 7
    		Inhibitor
    Anticonvulsant agent 7 (Compound 19) is an orally active broad-spectrum anticonvulsant that demonstrates excellent anticonvulsive activity in both the MES (maximal electroshock seizure) and 6 Hz epilepsy modelsmouse.
    Anticonvulsant agent 7
  • HY-N13768
    Nujiangefolin A
    Nujiangefolin A is a natural phenolic compound.
    Nujiangefolin A
  • HY-171845
    Chlorcyclamide
    Chlorcyclamide is a class of sulfonamide that can be used for the study of diabetes.
    Chlorcyclamide
  • HY-N17201
    Stelleranoid B
    Stelleranoid B is a natural flavonoid.
    Stelleranoid B
  • HY-125054
    Kelletinin A
    Kelletinin A is an active compound.
    Kelletinin A
  • HY-W223348
    Org-9768
    Org-9768 (Compound (2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine) is a drug intermediate for synthesizing the mitochondrial permeability transition pore (mPTP) inhibitor. Org-9768 can be used for the researches of neurological and cardiovascular disease, such as Parkinson's disease.
    Org-9768
  • HY-118608
    2α-Methyl androsterone
    2α-Methyl androsterone is an anabolic androgenic steroid metabolite of mesterolone and drostanolone.
    2α-Methyl androsterone
  • HY-129406
    AF 698
    AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice.
    AF 698
  • HY-B1504
    Acecarbromal
    Acecarbromal (Acetylcarbromal) is a Urea (HY-Y0271) derivative. Acecarbromal is a hypnotic and sedative agent.
    Acecarbromal
  • HY-123332
    YM-08050
    YM-08050 is a new anti-psychotic and Benzamide (HY-Z0283) derivative. YM-08050 inhibits stereotyped behaviors, conditioned avoidance responses, or spontaneous movements induced by Apomorphine (HY-12723) or Methamphetamine.
    YM-08050