2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-172848
    1(R)-Tetrahydrocannabidiphorol
    1(R)-Tetrahydrocannabidiphorol is a drug analogue and can be used for the research of neurological disease.
    1(R)-Tetrahydrocannabidiphorol
  • HY-N9673
    Epimedonin G
    Epimedonin G is a 2-phenoxychromone compound found in Epimedium brevicornum. Epimedonin G can be used for the research of cancer.
    Epimedonin G
  • HY-47824
    WAY-313165
    		98.0%
    WAY-313165 is an active molecule.
    WAY-313165
  • HY-B1700B
    (S,S)-Mivacurium dichloride
    (S,S)-Mivacurium dichloride (Compound 29a) is a neuromuscular blocking agent and causes muscle relaxation.
    (S,S)-Mivacurium dichloride
  • HY-N18255
    Timosaponin G
    Timosaponin G is a steroidal saponin found in the rhizomes of Anemarrhena asphodeloides.
    Timosaponin G
  • HY-105514
    KP-10614
    		Inhibitor
    KP-10614 is a potent, orally active platelet aggregation inhibitor. KP-10614 inhibits platelet aggregation induced by ADP with IC50 of 1 nM. KP-10614 causes dose-dependent inhibition of ex vivo platelet aggregation in rats. KP-10614 shows antithrombotic effects in various thrombosis models. KP-10614 can be used for thrombotic diseases research.
    KP-10614
  • HY-119651
    Perthane
    Perthane is an active compound.
    Perthane
  • HY-N17979
    5-Hydroxy-3′,4′,7,8-tetramethoxyflavone
    5-Hydroxy-3′,4′,7,8-tetramethoxyflavone is a flavone found in the whole plant of Peperomia sui. 5-Hydroxy-3′,4′,7,8-tetramethoxyflavone shows no activity against cancer cell lines in vitro.
    5-Hydroxy-3′,4′,7,8-tetramethoxyflavone
  • HY-N17209
    Taccalonolide Q
    Taccalonolide Q is a natural steroid.
    Taccalonolide Q
  • HY-N17643
    3,3',5,5'-Tetramethoxy-7,9':7',9-diepoxylignan-4,4'-di-O-β-D-glucopyranoside
    3,3',5,5'-Tetramethoxy-7,9':7',9-diepoxylignan-4,4'-di-O-β-D-glucopyranoside is a natural product that can be found in tulip tree.
    3,3',5,5'-Tetramethoxy-7,9':7',9-diepoxylignan-4,4'-di-O-β-D-glucopyranoside
  • HY-181059
    AMPK/mTOR modulator-1
    AMPK/mTOR modulator-1, Ginsenoside derivative, is an orally active mTOR inhibitor and AMPK activator. AMPK/mTOR modulator-1 activates AMPK signaling with a Kd of 4.759 μM. AMPK/mTOR modulator-1 promotes M1-like tumor-associated macrophage polarization while suppressing M2-like polarization. AMPK/mTOR modulator-1 can enhance glycolysis. AMPK/mTOR modulator-1 significantly inhibits tumor progression and shows anti-inflammation activity. AMPK/mTOR modulator-1 can be used for the research of colorectal cancer.
    AMPK/mTOR modulator-1
  • HY-N10985
    Xanthone V1a
    Xanthone V1a, a derivative of Xanthone (HY-N0126), is an antioxidant that can be found in the roots of Cudrania tricuspidata and twig extracts of Maclura fruticosa. Xanthone V1a exerts cytotoxic effects against colon, hepatocellular, and gastric carcinoma cells. Xanthone V1a exhibits scavenging activitys against DPPH and ABTS. Xanthone V1a can be used for the research of colon carcinoma, hepatocellular carcinoma, and gastric carcinoma.
    Xanthone V1a
  • HY-N17644
    Rubiarbonol L
    Rubiarbonol L is an arborinane-type triterpenoid found in the roots of Rubia yunnanensis.
    Rubiarbonol L
  • HY-122412
    Lenampicillin
    Lenampicillin is an active compound.
    Lenampicillin
  • HY-N17726
    Divaricatacid
    Divaricatacid is a cimifugin derivative (linear dihydrofurochromone-class compound) that can be found in Actaea species, excluding A. racemosa, A. americana, A. laciniata, and A. podocarpa. Divaricatacid serves as a chemical marker to distinguish Actaea species other than A. racemosa from authentic black cohosh (A. racemosa) products.
    Divaricatacid
  • HY-101045
    AT-112
    AT-112 is a ketotanserin analogue. AT-112 has hemodynamic effects. AT-112 significantly reduces portal vein branch blood flow and portal vein pressure. AT-112 can be used to study the pathogenesis of portal hypertension.
    AT-112
  • HY-178999
    Carnosol analog 1
    Carnosol analog 1 (Compound 10) is a derivative of carnosol. Carnosol analog 1 attenuates myotube atrophy (67.08% reversal) and adipocyte lipolysis in C26 tumor-conditioned models. Carnosol analog 1 alleviates cachexia-related weight loss without altering tumor progression in C26 tumor-bearing mice. Carnosol analog 1 can be used for the study of cancer cachexia.
    Carnosol analog 1
  • HY-171117
    1β-OH Glycine DCA
    1β-OH Glycine DCA (Compound Glyco 1β,3α,12α-triol) is a bile acid derivative.
    1β-OH Glycine DCA
  • HY-117712
    LG 6-101
    LG 6-101 is an orally active antiarrhythmic agent. LG 6-101 shows strong antiarrhythmic effects in a coronary-artery-ligation model of rats, better than Propafenone (HY-B0432). LG 6-101 also delays the occurence of ventricular premature beat (VPB)'s and has protective effects against cardiac arrest caused by aconitine.
    LG 6-101
  • HY-19844
    ANA-975
    ANA975, 5-amino-3-β -D-ribofuranosyl-3H-thiazolo[4,5-d]pyrimidin-2-one derivative, is an oral prodrug of the TLR-7 agonist Isatoribine (HY-13655A). ANA975 is converted to Isatoribine via a combined mechanism of hydrolysis by esterases and oxidation by aldehyde oxidase. ANA975 can be used in the research of hepatitis C virus infection.
    ANA-975