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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative 関連製品 (3822):

製品番号 製品名 製品効果 純度 構造式
  • HY-N9804
    3,3′,5-Trihydroxybibenzyl
    3,3′,5-Trihydroxybibenzyl is a natural phenolic compound.
    3,3′,5-Trihydroxybibenzyl
  • HY-W753481
    Guaiacol rutinoside
    Guaiacol rutinoside (compound GuRG) is a guaiacol glycoconjugate (rutinoside form) that can be found in the fruit, leaves, and shoots of Vitis vinifera cv. Monastrell.
    Guaiacol rutinoside
  • HY-129663
    L-687384
    L-687384 is an active compound.
    L-687384
  • HY-W012346
    Geranyl isobutyrate
    Geranyl isobutyrate is a synthetic α,β‑unsaturated branched‑chain aliphatic ester and a geraniol derivative. Geranyl isobutyrate acts as a food and feed flavouring agent and a biologically active antimicrobial compound. Geranyl isobutyrate shows antimicrobial activity against Gram‑positive and most Gram‑negative bacteria.
    Geranyl isobutyrate
  • HY-138178
    16-Oxolyclanitin-29-yl p-coumarate
    16-Oxolyclanitin-29-yl p-coumarate is a natural triterpene.
    16-Oxolyclanitin-29-yl p-coumarate
  • HY-N13815
    3,2'-Dihydroxy-4,5-dimethoxybibenzyl
    3,2'-Dihydroxy-4,5-dimethoxybibenzyl is a natural phenolic compound.
    3,2'-Dihydroxy-4,5-dimethoxybibenzyl
  • HY-N18040
    Esculentoside F
    Esculentoside F is a triterpene saponin found in the root of Phytolacca acinosa Roxb.
    Esculentoside F
  • HY-181475
    8,12-Iso-iPF2α-VI-1,5-lactone
    8,12-Iso-iPF2α-VI-1,5-lactone is a racemic mixture of the lactone form of the free acid 8,12-iso-iPF2α-VI, and is used in studies of immune-related diseases.
    8,12-Iso-iPF2α-VI-1,5-lactone
  • HY-N7303
    Aesculuside B
    Aesculuside B is a natural product that can be found in Aesculus chinensis?Bunge.
    Aesculuside B
  • HY-Y0123S5
    DL-Tyrosine-13C
    DL-Tyrosine-13C is the 13C-labeled DL-Tyrosine (HY-Y0123). DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine).
    DL-Tyrosine-<sup>13</sup>C
  • HY-122332
    2'-Fluoroaminopterin
    2'-Fluoroaminopterin is an active compound.
    2'-Fluoroaminopterin
  • HY-W145597
    D-Glucuronamide
    D-Glucuronamide is the derivate of D-glucuronic acid.
    D-Glucuronamide
  • HY-154978
    Cisplatin-resistant cells-IN-1
    Cisplatin-resistant cells-IN-1 (Compound 8) has high cytotoxicity against Cisplatin (HY-17394)-resistant cells. Cisplatin-resistant cells-IN-1 reduces the metabolic activity effectively in the low nanomolar range (IC50: 0.14-1.79 μM in A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR cells).
    Cisplatin-resistant cells-IN-1
  • HY-100835
    N-(4-Hydroxyphenylacetyl)spermine
    N-(4-Hydroxyphenylacetyl)spermine is an active compound.
    N-(4-Hydroxyphenylacetyl)spermine
  • HY-N17017
    Tinospin E
    Tinospin E is a natural diterpene.
    Tinospin E
  • HY-181041
    Multitarget AD-IN-5
    Multitarget AD-IN-5 (Compound 20), 9-Aminoacridine (HY-B1422) derivative, is a neuroprotective agent. Multitarget AD-IN-5 shows IC50 values of 0.614, 0.448, 3.73 and 1.55 μM for hAChE, hBChE, hMAO-A and hMAO-B. Multitarget AD-IN-5 can reduce length and diameter of Aβ42 fibers, and decrease the number of fibers per unit area. Multitarget AD-IN-5 can be used for research of Alzheimer's disease.
    Multitarget AD-IN-5
  • HY-W415753
    Alaptide
    Alaptide, a spirocyclic synthetic dipeptide and a derivative of melanocyte-stimulating hormone release-inhibiting factor (MIF), is a transdermal permeation modifier. Alaptide loaded on nanofibrous membranes accelerates the healing of skin incisions, particularly the healing of skin burns. Alaptide is a nootropic agent, that influences the dopaminergic system and increases homovanillic acid level in the striatum of rat models. Alaptide can be used for wound healing with large damaged areas and neurological diseases research.
    Alaptide
  • HY-169917
    THP-1/MV-4-11 against-1
    THP-1/MV-4-11 against-1 (compound 12k) is an anticancer agent with potency inhibitory against THP-1/MV/4 cells (IC50=29 nM and 98 nM, respectively). THP-1/MV-4-11 against-1 is one of 5-substituted thiazolyl urea derivatives, can be used in leukemic diseases research.
    THP-1/MV-4-11 against-1
  • HY-W436420
    WAY-299375 98.0%
    WAY-299375 is an active molecule for research into amyloid diseases and synucleinopathies.
    WAY-299375
  • HY-19031
    PCF-39
    PCF-39 is a Hypoxanthine (HY-N0091) derivative and immunomodulator agent. PCF-39 induces an increased spleen cellularity.
    PCF-39