2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N16713
    Heptaphylline
    Heptaphylline is a natural alkaloid.
    Heptaphylline
  • HY-128031
    Resolvin D1 methyl ester
    Resolvin D1 methyl ester (RvD1 methyl ester) is the methyl ester of Resolvin D1 (HY-125527). Resolvin D1 methyl ester reduces triglyceride levels.
    Resolvin D1 methyl ester
  • HY-110411
    Chlorproethazine hydrochloride
    Chlorproethazine hydrochloride is an orally active phenothiazine compound. Chlorproethazine hydrochloride can eliminate spasticity when administered intravenously and also effectively reduce rigidity in decerebrate cats. Chlorproethazine hydrochloride can be used in the research of neurological diseases.
    Chlorproethazine hydrochloride
  • HY-N16924
    Eriodictyol 7-O-β-D-glucuronide ethyl ester
    Eriodictyol 7-O-β-D-glucuronide ethyl ester is a natural flavonoid.
    Eriodictyol 7-O-β-D-glucuronide ethyl ester
  • HY-N8003A
    (2R,3S)-Pteroside C
    (2R,3S)-Pteroside C is a natural sesquiterpene.
    (2R,3S)-Pteroside C
  • HY-111744
    Deacetylanisomycin
    Deacetylanisomycin is a potent growth regulator in plants and an inactive derivative of Anisomycin. Anisomycin is a potent protein synthesis inhibitor .
    Deacetylanisomycin
  • HY-N16700
    (+)-Hinokinin
    (+)-Hinokinin (Compound 8) is a lignin compound found in Phyllanthus niruri.
    (+)-Hinokinin
  • HY-N16915
    Swertiajaponin 2''-O-rhamnoside
    Swertiajaponin 2''-O-rhamnoside (2''-O-Rhamnosylswertiajaponin) is a natural flavonoid.
    Swertiajaponin 2''-O-rhamnoside
  • HY-125924A
    DSPE-PEG20000-Amine ammonium
    DSPE-PEG20000-Amine ammonium is an amine derivative of phospholipid-polyethylene glycol, which is used to synthesize solid lipid and thermosensitive liposome nanoparticles for the delivery of anticancer agents. DSPE-PEG20000-Amine ammonium is applicable for cancer research.
    DSPE-PEG20000-Amine ammonium
  • HY-N18043
    Rehmaglutin C
    Rehmaglutin C is an iridoid lactone.Rehmaglutin C can be found in the dried root of Rehmannia glutinosa LiBosCH.
    Rehmaglutin C
  • HY-121626
    SKF 83692
    SKF 83692 is an active compound.
    SKF 83692
  • HY-N16994
    Gnemontanin F
    Gnemontanin F is a natural phenolic compound.
    Gnemontanin F
  • HY-P11124
    MGF24
    MGF24 is a modified protease-resistant MGF derivative. MGF24 protects dopaminergic neurons from 6-Hydroxydopamine (6-OHDA) (HY-113028)-induced apoptosis by inducing Heme oxygenase-1 (HO-1). MGF24 activates PKC-ε, which in turn activates Nrf2, up-regulating HO-1. MGF24 has neuroprotective activity and reduces myocardial infarct size in sheep models of myocardial ischemia. MGF24 can be used for neurological diseases like stroke, nerve injury and amyotrophic lateral sclerosis research.
    MGF24
  • HY-158576
    N-Cyclohexanecarbonyltetradecylamine
    N-Cyclohexanecarbonyltetradecylamine is an analog of N-cyclohexanecarbonyl-pentadecylamine, a selective inhibitor of acidic PEAase
    N-Cyclohexanecarbonyltetradecylamine
  • HY-N7941
    Celangulin II
    Celangulin II is a natural product that can be found in Tripterygium wilfordii Hook. f., Begonia spp..
    Celangulin II
  • HY-114705
    Ameltolide
    		98.56%
    Ameltolide (LY-201116; ADD 75073) is a novel anticonvulsant agent and can be used for epilepsy research.
    Ameltolide
  • HY-N19180
    Hancockiamide C
    Hancockiamide C is a phenylacetic piperazine natural products found in Aspergillus hancockii. Hancockiamide C is synthesized via the hkm biosynthetic gene cluster, involving NRPS Hkm11 and the acetyltransferase Hkm3. Hancockiamide C inhibits seed germination of Arabidopsis thaliana (MIC = 6.3 μg/mL), but shows no activity against Eragrostis tef seeds.
    Hancockiamide C
  • HY-N2836A
    (E)-Alepterolic acid
    (E)-Alepterolic acid is a natural product that can be found in Forsythia suspensa?(Thunb.) Vahl.
    (E)-Alepterolic acid
  • HY-121284
    Triazamate
    Triazamate is an active compound.
    Triazamate
  • HY-N17147
    Labda-8(17),12E,14-trien-16,15-olide
    Labda-8(17),12E,14-trien-16,15-olide is a natural diterpene.
    Labda-8(17),12E,14-trien-16,15-olide