2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D2432
    Mannose-PEG-Cy3
    Mannose-PEG-Cy3 is a Cy3 (HY-D0822) labeled Mannose-PEG.
    Mannose-PEG-Cy3
  • HY-D2848
    Chitosan-Cy5.5 (MW 2000)
    Chitosan-Cy5.5 (MW 2000) is a fluorescent dye composed of CY5.5 (HY-D0924) and chitosan. Chitosan-Cy5.5 (MW 2000) can be used for bioimaging, drug delivery and biomaterial research (Ex/Em = 680/710 nm).
    Chitosan-Cy5.5 (MW 2000)
  • HY-158726
    Complex 3
    Complex 3 is a fluorescent dithiocarbazate-copper complex with anticancer activity, which localizes to mitochondria. Complex 3 displays excitation/emission maxima of 455-495/535 nm, respectively. Complex 3 inhibits the growth of BxPC-3, AsPC-1, PANC-1, and WI38 pancreatic cancer cells with IC50 values of 0.74, 0.41, 0.62, and 2.06 µM, respectively. Complex 3 induces lipid peroxidation and mitochondrial rupture and shrinkage in AsPC-1 cells. Complex 3 also induces mitochondrial apoptosis and cytokine-cytokine receptor interaction dysfunction in AsPC-1 cells. Complex 3 reduces tumor volume in an AsPC-1 mouse xenograft model.
    Complex 3
  • HY-D2635
    Cy3 HA biotin 3000
    Cy3 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 550/570 nm).
    Cy3 HA biotin 3000
  • HY-D0660
    Acid red 131
    Acid red 131 is an acid dye that can be decolorized when aluminum sulfate is used as a coagulant.
    Acid red 131
  • HY-D2485
    Sulfo Cy3 bis COOH
    Sulfo Cy3 bis COOH is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
    Sulfo Cy3 bis COOH
  • HY-D2735
    QSY-9-succinimidyl ester
    QSY-9-succinimidyl ester is a nonfluorescent acceptor molecule with a terminal NHS ester group. QSY-9-succinimidyl ester has a wide and intense quenching range from 500-600 nm that makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with fluorescent dyes at 500 nm to 600 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
    QSY-9-succinimidyl ester
  • HY-130785
    LysoFP-NH2
    LysoFP-NH2 is a lysosomal-targeted fluorescent probe with amino acid functionalized derivatives. LysoFP-NH2 can be used to detect lysosomal NO levels in living cells.
    LysoFP-NH2
  • HY-137073
    Cy7 alkyne chloride
    Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds.
    Cy7 alkyne chloride
  • HY-D0683
    Direct yellow 28
    Direct yellow 28 is a good dyeing agent for cotton fabrics.
    Direct yellow 28
  • HY-D0388
    Acid Brown 5
    Acid Brown 5 is a brown dye whose staining effects can be removed by the electrocoagulation (EC) process.
    Acid Brown 5
  • HY-172284
    6-TAMRA cadaverine
    6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
    6-TAMRA cadaverine
  • HY-D0387
    Pigment Yellow 93
    Pigment Yellow 93 is a disazomethine dye with solid-state fluorescence.a biologically active chemical.
    Pigment Yellow 93
  • HY-D2623
    Cy3 HA (MW 7000)
    Cy3 HA (MW 7000) is a hyaluronic acid labeled with CY3 (HY-D0822). Cy3 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 550/570 nm).
    Cy3 HA (MW 7000)
  • HY-100041R
    Bromobimane (Standard)
    Bromobimane (Standard) is the analytical standard of Bromobimane (HY-100041). This product is intended for research and analytical applications. Bromobimane (Monobromobimane) is a nonfluorescent and converts into fluorescent products when reacts with thiols. Bromobimane has potential applications in labeling thiols.
    Bromobimane (Standard)
  • HY-D0451
    C.I. Direct orange 102
    C.I. Direct orange 102 is a good dyeing agent for cotton fabrics.
    C.I. Direct orange 102
  • HY-D2443
    AF594 DBCO
    AF594 DBCO is an AlexaFluor 594-conjugated DBCO click chemistry probe for fluorescent labeling of azido-modified cholesterol probes. DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection.
    AF594 DBCO
  • HY-D2422A
    Cy5.5-Paclitaxel
    Cy5.5-Paclitaxel is a Cy5.5 (HY-D0821) labeled Paclitaxel (HY-B0015).
    Cy5.5-Paclitaxel
  • HY-D2667
    Cy5.5 HA MA (MW 50000)
    Cy5.5 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY5.5 (HY-D0924). Cy5.5 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 680/710 nm).
    Cy5.5 HA MA (MW 50000)
  • HY-D2697
    Cy7.5 HA MA (MW 3000)
    Cy7.5 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY7.5 (HY-D0926). Cy7.5 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 770/820 nm).
    Cy7.5 HA MA (MW 3000)
Cat. No. Product Name / Synonyms Application Reactivity