2. シグナル伝達
  3. Immunology/Inflammation
  4. Human leukocyte immunoglobulin (Ig)-like receptors (LILR)
  5. Human leukocyte immunoglobulin (Ig)-like receptors (LILR) Inhibitor

Human leukocyte immunoglobulin (Ig)-like receptors (LILR) Inhibitor

Human leukocyte immunoglobulin (Ig)-like receptors (LILR) Isoform Comparison

Human leukocyte immunoglobulin (Ig)-like receptors (LILR) Inhibitors (4):

製品番号 製品名 製品効果 純度
  • HY-P99226
    Daxdilimab Inhibitor
    Daxdilimab is an anti-ILT7 monoclonal antibody, ILT7 is a cell surface molecule specific to the pDC type of dendritic cells. Daxdilimab can be used in acute lung injury (ALI) in patients with COVID-19 infection research.
  • HY-P991727
    Zamristobart Inhibitor
    Zamristobart is an anti-LILRB1 (leukocyte immunoglobulin-like receptor B1) IgG4κ type humanized antibody with immunostimulant and antineoplastic activities. The recommed isotype control is Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
  • HY-P99226A
    Daxdilimab (FUT8-KO) Inhibitor
    Daxdilimab (FUT8-KO) is an anti-ILT7 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.
  • HY-184157
    IB15C Inhibitor
    IB15C is an ILT3 (LILRB4) inhibitor with a human Kd of 0.92 μM. IB15C binds to a specific ILT3 pocket, disrupts ApoE interaction, and interferes with downstream inhibitory signaling pathways. IB15C reduces SHP1 and SHP2 phosphorylation, suppresses pro-inflammatory cytokine secretion, enhances amyloid uptake, and attenuates NF-κB activation. IB15C can be used for the research of alzheimer's disease.