2. Signaling Pathways
  3. Immunology/Inflammation
  4. Human leukocyte immunoglobulin (Ig)-like receptors (LILR)
  5. LILRB Isoform
  6. LILRB Inhibitor

LILRB Inhibitor

LILRB Inhibitor (1):

Cat. No. 상품명 효과 Purity
  • HY-184157
    IB15C
    		Inhibitor
    IB15C is an ILT3 (LILRB4) inhibitor with a human Kd of 0.92 μM. IB15C binds to a specific ILT3 pocket, disrupts ApoE interaction, and interferes with downstream inhibitory signaling pathways. IB15C reduces SHP1 and SHP2 phosphorylation, suppresses pro-inflammatory cytokine secretion, enhances amyloid uptake, and attenuates NF-κB activation. IB15C can be used for the research of alzheimer's disease.