Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds 関連製品 (10876):

製品番号	製品名	製品効果	純度	構造式

HY-P1339AS

Orexin B, human-¹³C₆,¹⁵N TFA
Orexin B, human-¹³C₆,¹⁵N (Human orexin B-¹³C₆,¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled Orexin B, human (HY-P1339). Orexin B, human is the agonist for Orexin Receptor, with K_is of 420 nM and 36 nM for OX1 and OX2. Orexin B, human participates in the regulation of appetite, wakefulness, cardiovascular function and neuroendocrine.

HY-100584S

Davercin-¹³C,d₃
Davercin-¹³C,d₃ (Erythromycin Cyclocarbonate-¹³C,d₃) is the ¹³C-labeled Davercin (HY-100584). Davercin (Erythromycin Cyclocarbonate), derivative of Erythromycin, which is active against Gram-positive and some Gram-negative microorganisms.

HY-143914S

N-Nitroso-Acebutolol-d₇
N-Nitroso-Acebutolol-d₇ is the deuterium labeled N-Nitroso-Acebutolol.

HY-135581S1

Raloxifene 6-glucuronide-d₄ lithium
Raloxifene 6-glucuronide-d₄ (lithium) is deuterium labeled Raloxifene 6-glucuronide. Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC₅₀ of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression.

HY-B1885S

Fenitrothion-d₆
Fenitrothion-d₆ is the deuterium labeled Fenitrothion (HY-B1885). Fenitrothion is a broad-spectrum and orally active insecticide/acaricide. Fenitrothion inhibits cholinesterase, AMPKα and IRS1/PI3K/AKT. Fenitrothion causes Apoptosis, reduces SOD activity. Fenitrothion shows insecticidal effect against Rhyzopertha dominica and Tribolium castaneum adults. Fenitrothion is widely used in cotton crops, vegetable crops, fruit crops and field crops, especially rice. Fenitrothion can be used for brain and spleen toxicology studies.

HY-18204S3

(Rac)-Valsartan-d₉
(Rac)-Valsartan-d₉ is deuterium labeled Valsartan. Valsartan (CGP 48933) is an angiotensin II receptor antagonist and has the potential for high blood pressure and heart failure research.

HY-150667S

2-Amino-6-(3-methoxy-anilino)purine-d₃
2-Amino-6-(3-methoxy-anilino)purine-d₃ is the deuterium labeled 2-Amino-6-(3-methoxy-anilino)purine.

HY-W699907

Pantoprazole sulfide-d₈
Pantoprazole sulfide-d₈ is the deuterium labeled Pantoprazole sulfide (HY-W016033). Pantoprazole sulfide is a metabolite of Pantoprazole (HY-17507), which is a proton-pump inhibitor.

HY-W724357

Napropamide-d₁₀
Napropamide-d₁₀ (Napropamid-d₁₀) is the deuterium labeled Napropamide (HY-B1972). Napropamide (Napropamid) is an amide herbicide that can be used to control weeds in fruits, vegetables, tobacco, and ornamental plants. Napropamide mainly exerts its effect by inhibiting DNA synthesis and cell division. Napropamide has moderate to high persistence in the field, with a half-life of 24-131 days, and is prone to photodegradation.

HY-W777620

1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone-¹³C,d₃
1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone-¹³C,d₃ (rac-Cotinine-¹³C,d₃) is the deuterium and ¹³C-labeled 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone (HY-W588192).

HY-B0106S

Levetiracetam-d₆
Levetiracetam-d₆ is the deuterium labeled Levetiracetam. Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent.

HY-113400S1

Cytidine diphosphate-¹³C₉ dilithium
Cytidine diphosphate-¹³C₉ dilithium is ¹³C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.

HY-128741S

D-Allose-¹³C
D-Allose-¹³C is the ¹³C labeled D-Allose (HY-128741). D-Allose exhibits antitumor activity against various cancer cells. D-Allose scavenges reactive oxygen species (ROS) and reduces oxidative stress damage. D-Allose exhibits anti-inflammatory and neuroprotective through inhibition of TLR4/PI3K/AKT signaling pathway. D-Allose exhibits antihypertensive, cryoprotective, and anti-osteoporotic activities.

HY-17474AS

Parecoxib-d₅ sodium
Parecoxib-d₅ sodium is the deuterium labeled Parecoxib sodium. Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.

HY-113958S

Difethialone-d₄
Difethialone-d₄ (Baraki-d₄; LM 2219-d₄) is the deuterium labeled Difethialone (HY-113958). Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts.

HY-W701580

6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione-d₃
6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione-d₃ (6-Amino-3-methyluracil-d₃) is the deuterium labeled 6-Amino-3-methylpyrimidine-2,4(1H,3H)-dione (HY-W038777).

HY-W005059S

2-(4-Aminophenyl)ethanol-d₆
2-(4-Aminophenyl)ethanol-d₆ (p-aminophenylethanol-d₆) is the deuterium labeled 2-(4-Aminophenyl)ethanol (HY-W005059). 2-(4-Aminophenyl)ethanol is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-132956S

Tigloyl-L-carnitine-d₃ chloride
Tigloyl-L-carnitine-d₃ (chloride) is the deuterium labeled Tigloyl-L-carnitine chloride.

HY-126199S

(Z)-Tetrachlorvinphos-d₆
(Z)-Tetrachlorvinphos-d₆ is the deuterium labeled Tetrachlorvinphos (HY-126199). Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals.

HY-W012570S

Decyl aldehyde-d₂
Decyl aldehyde-d₂ is deuterated labeled Decyl aldehyde (HY-W012570). Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.

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