1. Others Neuronal Signaling GPCR/G Protein
  2. Orexin Receptor (OX Receptor) Isotope-Labeled Compounds
  3. Orexin B, human-13C6,15N TFA

Orexin B, human-13C6,15N TFA  (Synonyms: Human orexin B-13C6,15N TFA)

Cat. No.: HY-P1339AS
Handling Instructions Technical Support

Orexin B, human-13C6,15N (Human orexin B-13C6,15N) TFA is the 13C- and 15N-labeled Orexin B, human (HY-P1339). Orexin B, human is the agonist for Orexin Receptor, with Kis of 420 nM and 36 nM for OX1 and OX2. Orexin B, human participates in the regulation of appetite, wakefulness, cardiovascular function and neuroendocrine.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Orexin B, human-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N TFA

Orexin B, human-13C6,15N TFA Chemical Structure

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Description

Orexin B, human-13C6,15N (Human orexin B-13C6,15N) TFA is the 13C- and 15N-labeled Orexin B, human (HY-P1339). Orexin B, human is the agonist for Orexin Receptor, with Kis of 420 nM and 36 nM for OX1 and OX2. Orexin B, human participates in the regulation of appetite, wakefulness, cardiovascular function and neuroendocrine[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2906.33 (free base)

Formula

C117 13C6H212N44 15NO35S·xC2HF3O2

Sequence

Arg-Ser-Gly-Pro-Pro-Gly-{Leu-13C6,15N}-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2

Sequence Shortening

RSGPPG-{Leu-13C6,15N}-QGRLQRLLQASGNHAAGILTM-NH2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Orexin B, human-13C6,15N TFA
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HY-P1339AS
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