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  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds 関連製品 (10873):

製品番号 製品名 製品効果 純度 構造式
  • HY-W702947
    1-Nitrosopiperidine-d4
    1-Nitrosopiperidine-d4 is the deuterium labeled 1-Nitrosopiperidine (HY-W150598).
    1-Nitrosopiperidine-d<sub>4</sub>
  • HY-N0589S
    Dehydrodiisoeugenol-d4
    Dehydrodiisoeugenol-d4 is the deuterium labeled Dehydrodiisoeugenol (HY-N0589). Dehydrodiisoeugenol is an orally active anti-inflammatory and anti-tumor agent. Dehydrodiisoeugenol inhibits the proliferation of colorectal cancer cells, and induces apoptosis, autophagy, endoplasmic reticulum stress and cell cycle arrest. Dehydrodiisoeugenol also exerts anti-inflammatory effects by inhibiting the activation of NF-κB and the expression of COX-2. Dehydrodiisoeugenol can be used in the research related to colorectal cancer, inflammatory diseases and ulcerative colitis.
    Dehydrodiisoeugenol-d<sub>4</sub>
  • HY-123669AS
    (R)-trans-138727-d4
    (R)-trans-138727-d4 is the deuterium labeled (R)-trans-138727.
    (R)-trans-138727-d<sub>4</sub>
  • HY-14870S3
    Selexipag-d6
    Selexipag-d6 is deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor).
    Selexipag-d<sub>6</sub>
  • HY-W742901
    2,2'-Bis(hydroxyphenyl)methane-d4
    2,2'-Bis(hydroxyphenyl)methane-d4 is the deuterium labeled 2,2’-Bis(hydroxyphenyl)methane (HY-112034).
    2,2'-Bis(hydroxyphenyl)methane-d<sub>4</sub>
  • HY-W010736S
    1,2-Dipalmitoyl-sn-glycerol-d9
    1,2-Dipalmitoyl-sn-glycerol-d9 is a deuterated labeled 1,2-Dipalmitoyl-sn-glycerol. 1,2-Dipalmitoyl-sn-glycerol is an endogenous metabolite.
    1,2-Dipalmitoyl-sn-glycerol-d<sub>9</sub>
  • HY-W700136
    N-(4-(Benzyloxy)-3-(methylthio)phenyl)acetamide-d3
    N-(4-(Benzyloxy)-3-(methylthio)phenyl)acetamide-d3 is the deuterium labeled N-(4-(Benzyloxy)-3-(methylthio)phenyl)acetamide (HY-W699901).
    N-(4-(Benzyloxy)-3-(methylthio)phenyl)acetamide-d<sub>3</sub>
  • HY-133707S
    β-Muricholic acid-d5
    β-Muricholic acid-d5 is the deuterium labeled β-Muricholic acid.
    β-Muricholic acid-d<sub>5</sub>
  • HY-W768990
    Vinclozolin-13C3,d3
    Vinclozolin-13C3,d3 is the deuterium and 13C-labeled Vinclozolin (HY-B2061).
    Vinclozolin-<sup>13</sup>C<sub>3</sub>,d<sub>3</sub>
  • HY-W101563S
    Propan-2-amine-d6 hydrochloride 98.43%
    Propan-2-amine-d6 hydrochloride is the deuterium labeled Propan-2-amine.
    Propan-2-amine-d<sub>6</sub> hydrochloride
  • HY-W178868S
    Lodoxamide impurity 1-d5
    Lodoxamide impurity 1-d5 is deuterium labeled n-Ethyl-2-hydroxyacetamide.
    Lodoxamide impurity 1-d<sub>5</sub>
  • HY-W700648
    Zolpidem phenyl-4-carboxylic acid-d6
    Zolpidem phenyl-4-carboxylic acid-d6 is the deuterium labeled 4-(3-(2-(Dimethylamino)-2-oxoethyl)-6-methylimidazo[1,2-a]pyridin-2-yl)benzoic acid (HY-W700647).
    Zolpidem phenyl-4-carboxylic acid-d<sub>6</sub>
  • HY-W699813
    3β-Ursodeoxycholic acid-d5
    3β-Ursodeoxycholic acid-d5 (Isoursodeoxycholic acid-d5) is the deuterium labeled 3β-Ursodeoxycholic acid.
    3β-Ursodeoxycholic acid-d<sub>5</sub>
  • HY-12751S
    Trimethobenzamide-d6
    Trimethobenzamide-d6 is deuterium labeled Trimethobenzamide. Trimethobenzamide is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
    Trimethobenzamide-d<sub>6</sub>
  • HY-12296S
    Navtemadlin-d7
    Navtemadlin-d7 is the deuterium labeled Navtemadlin. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM.
    Navtemadlin-d<sub>7</sub>
  • HY-W778990
    2-Deoxyuridine-1,2,3,4,5-13C5
    2-Deoxyuridine-1,2,3,4,5-13C5 is the 13C-labeled 2'-Deoxyuridine (HY-D0186). 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD).
    2-Deoxyuridine-1,2,3,4,5-<sup>13</sup>C<sub>5</sub>
  • HY-W015824S3
    DL-Aspartic acid-13C1
    DL-Aspartic acid-13C1 is the 13C labeled DL-Aspartic acid.
    DL-Aspartic acid-<sup>13</sup>C<sub>1</sub>
  • HY-N6741S
    β-Zearalenol-13C18
    β-Zearalenol-13C18 is the 13C-labeled β-Zearalenol. β-Zearalenol is a non-steroidal estrogenic mycotoxin synthesized by Fusarium species. β-Zearalenol potentially influences transcription and effects gene expression on translational level.
    β-Zearalenol-<sup>13</sup>C<sub>18</sub>
  • HY-17507S1
    Pantoprazole-d3
    Pantoprazole-d3 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
    Pantoprazole-d<sub>3</sub>
  • HY-144561S
    6α,3'-p-Dihydroxy paclitaxel-d5
    6α,3'-p-Dihydroxy paclitaxel-d5 is the deuterium labeled 6α,3′-p-Dihydroxypaclitaxel (HY-N11628).
    6α,3'-p-Dihydroxy paclitaxel-d<sub>5</sub>