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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Z9003S
    Indomethacin ethyl ester-d4
    Indomethacin ethyl ester-d4 is the deuterium labeled Indomethacin ethyl ester.
    Indomethacin ethyl ester-d<sub>4</sub>
  • HY-143981S
    15-Hydroxy Lubiprostone-d7
    15-Hydroxy Lubiprostone-d7 is the deuterium labeled 15-Hydroxy Lubiprostone.
    15-Hydroxy Lubiprostone-d<sub>7</sub>
  • HY-17573S
    Carbetocin-d7
    Carbetocin-d7 is the deuterium labeled Carbetocin (HY-17573). Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS.
    Carbetocin-d<sub>7</sub>
  • HY-W345136S
    Didesmethylsibutramine-d7
    Didesmethylsibutramine-d7 is the deuterium labeled Didesmethylsibutramine.
    Didesmethylsibutramine-d<sub>7</sub>
  • HY-15284S
    Prasugrel-d5
    Prasugrel-d5 is deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation.
    Prasugrel-d<sub>5</sub>
  • HY-77956S4
    Thyminose-d3
    Thyminose-d3 is the deuterium labeled Thyminose. Thyminose is an endogenous metabolite.
    Thyminose-d<sub>3</sub>
  • HY-W746556
    Methyl cholate-d5
    Methyl cholate-d5 is the deuterium labeled Methyl cholate. Methyl cholate is a bile acid analog and a specific inhibitor of TcdB toxin from Clostridioides difficile. Methyl cholate exerts a stronger selective inhibitory effect on TcdB than on TcdA. Methyl cholate induces conformational stabilization by binding to a unique site of TcdB, thereby blocking the binding of the toxin to host receptors and its self-processing process. Methyl cholate effectively protects human fibroblasts from TcdB-induced cytopathic effects. Methyl cholate exhibits dose-dependent anti-hepatic fibrosis activity in both cellular and zebrafish models, and significantly reduces the expression levels of α-SMA and COL-I. Methyl cholate is suitable for in-depth research in the fields of Clostridioides difficile infection and hepatic fibrosis.
    Methyl cholate-d<sub>5</sub>
  • HY-W740756
    N-Ethyl-3,4-(methylenedioxy)aniline-d5
    N-Ethyl-3,4-(methylenedioxy)aniline-d5 (N-Ethyl-3H-1,2-benzodioxol-6-amine-d5) is the deuterium labeled N-Ethylbenzo[d][1,3]dioxol-5-amine (HY-W015360).
    N-Ethyl-3,4-(methylenedioxy)aniline-d<sub>5</sub>
  • HY-W008253S3
    5-Hydroxyindole-3-acetic acid-13C6
    5-Hydroxyindole-3-acetic acid-13C6 is the 13C-labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
    5-Hydroxyindole-3-acetic acid-<sup>13</sup>C<sub>6</sub>
  • HY-147338S2
    5-Methylcytidine 5′-triphosphate-d8 trisodium
    5-Methylcytidine 5'-triphosphate-d8 trisodium is the deuterium-labeled form of 5-Methylcytidine 5'-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5'-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5'-triphosphate trisodium can be used to replace unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells.
    5-Methylcytidine 5′-triphosphate-d<sub>8</sub> trisodium
  • HY-151187S
    4-n-Butylanisole-2,3,5,6-d4
    4-n-Butylanisole-2,3,5,6-d4 is the deuterium labeled 4-n-Butylanisole.
    4-n-Butylanisole-2,3,5,6-d<sub>4</sub>
  • HY-W013326S
    Bisphenol Z-d6
    Bisphenol Z-d6 is the deuterium labeled 4,4'-(Cyclohexane-1,1-diyl)diphenol (HY-W013326).
    Bisphenol Z-d<sub>6</sub>
  • HY-10002AS2
    (1S)-Calcitriol-d6
    (1S)-Calcitriol-d6 (1α,25-Dihydroxy-3-epi-vitamin D3-d6) is the deuterium labeled (1S)-Calcitriol (HY-10002A). (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion.
    (1S)-Calcitriol-d<sub>6</sub>
  • HY-W740246
    2-Butyl-4-chloro-5-formylimidazole-d3
    2-Butyl-4-chloro-5-formylimidazole-d3 is the deuterium labeled 2-Butyl-4-chloro-5-formylimidazole (HY-W016155). 2-Butyl-4-chloro-5-formylimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    2-Butyl-4-chloro-5-formylimidazole-d<sub>3</sub>
  • HY-W013809S
    Ethyl stearate-d35
    Ethyl stearate-d35 is the deuterium labeled Ethyl stearate.
    Ethyl stearate-d<sub>35</sub>
  • HY-W777978
    2-Bromo-3'-methoxyacetophenone-13C,d3
    2-Bromo-3'-methoxyacetophenone-13C,d3 (α-Bromo-3'-methoxyacetophenone-13C,d3) is the deuterium and 13C labeled 2-Bromo-3'-methoxyacetophenone (HY-W004800).
    2-Bromo-3'-methoxyacetophenone-<sup>13</sup>C,d<sub>3</sub>
  • HY-P0059S
    Teriparatide-d10
    Teriparatide-d10 (Human parathyroid hormone-(1-34)-d10) is the deuterium labeled Teriparatide (HY-P0059). Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research.
    Teriparatide-d<sub>10</sub>
  • HY-W012444S
    Glyceryl 1-monooctanoate-d15
    Glyceryl 1-monooctanoate-d15 is the deuterium labeled Glyceryl 1-monooctanoate (HY-W012444). Glyceryl 1-monooctanoate is a glycerol monolaurate derivative. Glyceryl 1-monooctanoate is a broad-spectrum antimicrobial, suppresses the growth of pathogenic yeast (Candida albicans and Candida parapsilosis), as well as Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli, Klebsiella pneumoniae) bacteria.
    Glyceryl 1-monooctanoate-d<sub>15</sub>
  • HY-Y0842S4
    Formamide-d1
    Formamide-d1 is the deuterium labeled Formamide (HY-Y0842). Formamide is an effective DNA denaturant that significantly reduces the stability of DNA in buffer solutions. Formamide can also be used as a decalcifying agent for rat cardiac cells. Additionally, formamide is widely used as a solvent or chemical raw material for ion compounds, resins, and plasticizers.
    Formamide-d<sub>1</sub>
  • HY-40354S1
    Tofacitinib-13C3,15N
    99.57%
    Tofacitinib-13C3,15N (Tasocitinib-13C3,15N) is 13C and 15N labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
    Tofacitinib-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N