2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-17465S
    Glycopyrrolate-d5 bromide
    		99.37%
    Glycopyrrolate-d5 (bromide) is deuterium labeled Glycopyrrolate.
    Glycopyrrolate-d<sub>5</sub> bromide
  • HY-N0832S1
    L-Histidine-13C6,15N3
    L-Histidine-13C6,15N3 is 13C and 15N-labeled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
    L-Histidine-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>3</sub>
  • HY-17034AS
    Dexmedetomidine-13C,d3 hydrochloride
    		99.93%
    Dexmedetomidine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Dexmedetomidine (hydrochloride). Dexmedetomidine hydrochloride ((+)-Medetomidine hydrochloride) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine hydrochloride shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine hydrochloride exhibits anxiolysis, sedation, and modest analgesia effects.
    Dexmedetomidine-<sup>13</sup>C,d<sub>3</sub> hydrochloride
  • HY-18206S
    Lisinopril-d5
    Lisinopril-d5 is the deuterium labeled Lisinopril. Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
    Lisinopril-d<sub>5</sub>
  • HY-10208S
    Pazopanib-d6
    		98.0%
    Pazopanib-d6 is the deuterium labeled Pazopanib. Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
    Pazopanib-d<sub>6</sub>
  • HY-W010031S1
    1-Methyluric acid-d3
    1-Methyluric acid-d3 is the deuterium labeled 1-Methyluric acid (HY-W010031). 1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.
    1-Methyluric acid-d<sub>3</sub>
  • HY-W710638
    Pentane-1,5-diamine-15N2 dihydrochloride
    Pentane-1,5-diamine-15N2 dihydrochloride is the 15N-labeled Pentane-1,5-diamine dihydrochloride (HY-W016750). Pentane-1,5-diamine dihydrochloride is an endogenous metabolite.
    Pentane-1,5-diamine-<sup>15</sup>N<sub>2</sub> dihydrochloride
  • HY-N10634S
    D-Glucosyl-β-N-palmitoylsphingosine-d3
    D-Glucosyl-β-N-palmitoylsphingosine-d3 (N-ω-CD3-Hexadecaoyl-glucopsychosie) is deuterium labeled D-Glucosyl-β-1,1′-N-palmitoylsphingosine (HY-N10634). D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl(β) Ceramide (d18:1/16:0)) is an endogenous Mincle ligand possessing immunostimulatory activity.
    D-Glucosyl-β-N-palmitoylsphingosine-</sub>d<sub>3</sub>
  • HY-N0186S3
    Indole-3-butyric acid-d2
    		99.79%
    Indole-3-butyric acid-d2 (Indolebutyric acid-d2) is the deuterium labeled Indole-3-butyric acid (HY-N0186). Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process.
    Indole-3-butyric acid-d<sub>2</sub>
  • HY-12678S
    Entrectinib-d4
    Entrectinib-d4 (NMS-E628-d4; RXDX-101-d4) is the deuterium labeled Entrectinib (HY-12678). Entrectinib is an orally active, BBB-penetrated and centrally active inhibitor of TrkA/B/C, ROS1 and ALK, with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Entrectinib induces apoptosis and cycle arrest in cancer cells, has antitumor activity, and attenuates bleomycin-induced lung fibrosis in mice.
    Entrectinib-d<sub>4</sub>
  • HY-150631S
    Glutathione-glycine-13C2,15N trifluoroacetate
    		99.86%
    Glutathione-glycine-13C2,15N (trifluoroacetate) is the 13C and 15N labeled Glutathione-glycine trifluoroacetate.
    Glutathione-glycine-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N trifluoroacetate
  • HY-176415S
    Cys-MC-GGFG-Dxd-d5
    Cys-MC-GGFG-Dxd-d5 is the deuterium labeled Cys-MC-GGFG-Dxd (HY-176415). Cys-MC-GGFG-Dxd is a conjugate of Cys and Deruxtecan (HY-13631E). Cys-MC-GGFG-Dxd is a linker-toxin building block in antibody-drug conjugates (ADCs) used to link antibody Cys residues to cytotoxic drugs. Cys-MC-GGFG-Dxd can be used in cancer research.
    Cys-MC-GGFG-Dxd-d<sub>5</sub>
  • HY-W087940S
    Benzene-1,2,4,5-tetracarboxylic acid-d6
    		99.8%
    Benzene-1,2,4,5-tetracarboxylic acid-d6 is the deuterium labeled Benzene-1,2,4,5-tetracarboxylic acid.
    Benzene-1,2,4,5-tetracarboxylic acid-d<sub>6</sub>
  • HY-10917S
    GW2580-d6
    		98.36%
    GW2580-d6 is the deuterium labeled GW2580. GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling.
    GW2580-d<sub>6</sub>
  • HY-125818S4
    Cytidine-5'-triphosphate-d14 dilithium
    		98.2%
    Cytidine-5'-triphosphate-d14 (Cytidine triphosphate-d14 dilithium; 5'-CTP-d14) dilithium is deuterium labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
    Cytidine-5'-triphosphate-d<sub>14</sub> dilithium
  • HY-N7403S
    N-(3-Phenylpropionyl)glycine-d2
    		99.64%
    N-(3-Phenylpropionyl)glycine-d2 is the deuterium labeled N-(3-Phenylpropionyl)glycine.
    N-(3-Phenylpropionyl)glycine-d<sub>2</sub>
  • HY-17413S2
    Zidovudine-d4
    Zidovudine-d4 is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.
    Zidovudine-d<sub>4</sub>
  • HY-127035S3
    Tristearin-d5
    		98.93%
    Tristearin-d5 is the deuterium labeled Tristearin (HY-127035). Tristearin is a triglyceride derived from three units of stearic acid.
    Tristearin-d<sub>5</sub>
  • HY-125774S
    Bimatoprost acid-d4
    Bimatoprost acid-d4 (17-Phenyl trinor PGF2α-d4) is the deuterium labeled Bimatoprost acid.
    Bimatoprost acid-d<sub>4</sub>
  • HY-142907S
    (2-Fluoro-4-biphenyl)acetic acid-d5
    		99.64%
    (2-Fluoro-4-biphenyl)acetic acid-d5 is the deuterium labeled (2-Fluoro-4-biphenyl)acetic acid.
    (2-Fluoro-4-biphenyl)acetic acid-d<sub>5</sub>