Glycopyrrolate-d₅ bromide (Synonyms: Glycopyrronium-d5 bromide)

Name: Glycopyrrolate-d 5 bromide
Brand: MedChemExpress
SKU: HY-17465S
Rating: 4.5 (1 reviews)

Cat. No.: HY-17465S Purity: 99.37%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Glycopyrrolate-d₅ (bromide) is deuterium labeled Glycopyrrolate.

For research use only. We do not sell to patients.

Glycopyrrolate-d₅ bromide Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote
50 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Glycopyrrolate-d₅ bromide:

Glycopyrrolate In-stock
Glycopyrrolate (Standard) Get quote

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

Biological Activity
Purity & Documentation
References
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Description

Glycopyrrolate-d₅ (bromide) is deuterium labeled Glycopyrrolate.

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

403.37

Formula

C₁₉H₂₃D₅BrNO₃

Unlabeled CAS

596-51-0

Appearance

Solid

Color

White to off-white

SMILES

C[N+]1(C)CC(OC(C(O)(C2CCCC2)C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=O)CC1.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (247.91 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4791 mL	12.3956 mL	24.7911 mL
5 mM	0.4958 mL	2.4791 mL	4.9582 mL
10 mM	0.2479 mL	1.2396 mL	2.4791 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.37%

Select Batch:

Data Sheet (278 KB) SDS (252 KB)

COA (257 KB) HNMR (139 KB) RP-HPLC (169 KB) LCMS (91 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Haddad, E.B., et al., Pharmacological characterization of the muscarinic receptor antagonist, glycopyrrolate, in human and guinea-pig airways. Br J Pharmacol, 1999. 127(2): p. 413-20. [Content Brief]

[3]. Neverlien, P.O., et al., Glycopyrrolate treatment of drooling in an adult male patient with cerebral palsy. Clin Exp Pharmacol Physiol, 2000. 27(4): p. 320-2. [Content Brief]

[4]. Olsen, A.K. and P. Sjogren, Oral glycopyrrolate alleviates drooling in a patient with tongue cancer. J Pain Symptom Manage, 1999. 18(4): p. 300-2. [Content Brief]

[5]. Kumar, M.G., et al., Oral Glycopyrrolate for Refractory Pediatric and Adolescent Hyperhidrosis. Pediatr Dermatol, 2013. [Content Brief]

[6]. Garnock-Jones, K.P., Glycopyrrolate oral solution: for chronic, severe drooling in pediatric patients with neurologic conditions. Paediatr Drugs, 2012. 14(4): p. 263-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.4791 mL	12.3956 mL	24.7911 mL	61.9778 mL
	5 mM	0.4958 mL	2.4791 mL	4.9582 mL	12.3956 mL
	10 mM	0.2479 mL	1.2396 mL	2.4791 mL	6.1978 mL
	15 mM	0.1653 mL	0.8264 mL	1.6527 mL	4.1319 mL
	20 mM	0.1240 mL	0.6198 mL	1.2396 mL	3.0989 mL
	25 mM	0.0992 mL	0.4958 mL	0.9916 mL	2.4791 mL
	30 mM	0.0826 mL	0.4132 mL	0.8264 mL	2.0659 mL
	40 mM	0.0620 mL	0.3099 mL	0.6198 mL	1.5494 mL
	50 mM	0.0496 mL	0.2479 mL	0.4958 mL	1.2396 mL
	60 mM	0.0413 mL	0.2066 mL	0.4132 mL	1.0330 mL
	80 mM	0.0310 mL	0.1549 mL	0.3099 mL	0.7747 mL
	100 mM	0.0248 mL	0.1240 mL	0.2479 mL	0.6198 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Glycopyrrolate-d₅ bromide Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glycopyrrolate-d₅Glycopyrronium-d5Isotope-Labeled CompoundsmAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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Glycopyrrolate-d5 bromide (Synonyms: Glycopyrronium-d5 bromide)

Customer Review

Other Forms of Glycopyrrolate-d5 bromide:

Glycopyrrolate-d5 bromide Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All mAChR Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review

Glycopyrrolate-d5 bromide Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Glycopyrrolate-d5 bromide Related Classifications

Keywords:

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Glycopyrrolate-d₅ bromide (Synonyms: Glycopyrronium-d5 bromide)

Other Forms of Glycopyrrolate-d₅ bromide:

Glycopyrrolate-d₅ bromide Related Antibodies

Glycopyrrolate-d₅ bromide Related Antibodies

Glycopyrrolate-d₅ bromide Related Classifications