2. Signaling Pathways
  3. Others
  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (11062):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-107384AR
    Asimadoline hydrochloride (Standard)
    Asimadoline hydrochloride (Standard) (EMD-61753 hydrochloride (Standard)) is the analytical standard of Asimadoline (hydrochloride) (HY-107384A). This product is intended for research and analytical applications. Asimadoline (EMD-61753) hydrochloride is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Asimadoline hydrochloride has low permeability across the blood brain barrier and has peripheral anti-inflammatory actions. Asimadoline hydrochloride ameliorates allodynia in diabetic rats and has the potential for irritable bowel syndrome (IBS).
    Asimadoline hydrochloride (Standard)
  • HY-103082R
    CLK1-IN-1 (Standard)
    CLK1-IN-1 (Standard) is the analytical standard of CLK1-IN-1 (HY-103082). This product is intended for research and analytical applications. CLK1-IN-1 is a potent and selective of Cdc2-like kinase 1 (CLK1) inhibitor, with an IC50 of 2 nM.
    CLK1-IN-1 (Standard)
  • HY-108341AR
    PF-06424439 methanesulfonate (Standard)
    PF-06424439 methanesulfonate (Standard) is the analytical standard of PF-06424439 (methanesulfonate) (HY-108341A). This product is intended for research and analytical applications. PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. PF-06424439 methanesulfonate is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate.
    PF-06424439 methanesulfonate (Standard)
  • HY-107471R
    CB2 receptor agonist 3 (Standard)
    CB2 receptor agonist 3 (Standard) is the analytical standard of CB2 receptor agonist 3 (HY-107471). This product is intended for research and analytical applications. CB2 receptor agonist 3 is a robust and selective CB2 cannabinoid agonist with Kis of 7.6 and 900 nM for CB2 and CB1, respectively. CB2 receptor agonist 3 significantly increases P-ERK 1/2 expression in HL-60 cells.
    CB2 receptor agonist 3 (Standard)
  • HY-131101R
    Nor-Acetildenafil (Standard)
    Nor-Acetildenafil (Standard) is the analytical standard of Nor-Acetildenafil. This product is intended for research and analytical applications. Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor.
    Nor-Acetildenafil (Standard)
  • HY-78446R
    KSD 2405 (Standard)
    KSD 2405 (Standard) is the analytical standard of KSD 2405. This product is intended for research and analytical applications. KSD 2405 is an endogenous metabolite.
    KSD 2405 (Standard)
  • HY-A0020R
    Eldecalcitol (Standard)
    Eldecalcitol (Standard) is the analytical standard of Eldecalcitol. This product is intended for research and analytical applications. Eldecalcitol (ED-71) is an orally active vitamin D3 analogue, inhibits bone resorption and increases bone mineral density. Eldecalcitol (ED-71) displays anti-tumor effect and inhibits cell proliferation, migration and induces apoptosis by suppressing GPx-1.
    Eldecalcitol (Standard)
  • HY-15340R
    LG100268 (Standard)
    LG100268 (Standard) is the analytical standard of LG100268. This product is intended for research and analytical applications. LG100268 (LG268) is a potent, selective and orally active retinoid X receptor (RXR) agonist with EC50 values of 4 nM, 3 nM, and 4 nM for RXR-α, RXR-β, and RXR-γ, respectively. LG100268 displays >1000-fold selectivity for RXR over RAR, the Ki values are 3.4 nM, 6.2 nM and 9.2 nM for RXR-α, RXR-β, and RXR-γ, respectively. LG100268 activates RXR homodimers to induce transcriptional activation. LG100268 can be used for the study of lung carcinogenesisy.
    LG100268 (Standard)
  • HY-W003303R
    (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine (Standard)
    (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine (Standard) is the analytical standard of (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine (HY-W003303). This product is intended for research and analytical applications.
    (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine (Standard)
  • HY-B1244R
    Dimetridazole (Standard)
    Dimetridazole (Standard) is the analytical standard of Dimetridazole (HY-B1244). This product is intended for research and analytical applications. Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections.
    Dimetridazole (Standard)
  • HY-B1768R
    Succimer (Standard)
    Succimer (Standard) is the analytical standard of Succimer. This product is intended for research and analytical applications. Succimer is a widely used chelating agent for the treatment of Pb poisoning.
    Succimer (Standard)
  • HY-12199R
    Pitolisant (Standard)
    Pitolisant (Standard) is the analytical standard of Pitolisant. This product is intended for research and analytical applications. Pitolisant is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (Ki=0.16 nM).
    Pitolisant (Standard)
  • HY-15900R
    Voxtalisib (Standard)
    Voxtalisib (Standard) is the analytical standard of Voxtalisib. This product is intended for research and analytical applications. Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.
    Voxtalisib (Standard)
  • HY-W099331R
    Monoethylglycinexylidide hydrochloride (Standard)
    Benfuracarb (Standard) is the analytical standard of Benfuracarb. This product is intended for research and analytical applications. Benfuracarb is a broad-spectrum carbamate insecticide with crop protection activity. Benfuracarb is used to control springtails, aphids, and other pests, typically on sugar beet crops. Benfuracarb exhibits toxicity to humans and aquatic organisms. Benfuracarb exposure to zebrafish embryos resulted in a reduction in the body length of zebrafish larvae. Superoxide dismutase (SOD) activity was significantly increased after Benfuracarb treatment. Benfuracarb also interfered with the transcriptional levels of marker genes associated with early embryonic development.
    Monoethylglycinexylidide hydrochloride (Standard)
  • HY-121214R
    Amisulbrom (Standard)
    Amisulbrom (Standard) is the analytical standard of Amisulbrom (HY-121214). Amisulbrom is a fungicide. Amisulbrom can inhibit the cytochrome-bc1 complex of the mitochondrial electron and induce mitochondrial dysfunction. Amisulbrom can induce cell apoptosis, ROS production and cause G2/M phase arrest. Amisulbrom shows cardiovascular toxicity to zebrafish. Amisulbrom can be used for the researches of infection and cardiovascular disease.
    Amisulbrom (Standard)
  • HY-I0434R
    Cinacalcet impurity 1 (Standard)
    [(1R)-1-(naphthalen-1-yl)ethyl]bis({3-[3-(trifluoromethyl)phenyl]propyl})amine (Standard) is the analytical standard of [(1R)-1-(naphthalen-1-yl)ethyl]bis({3-[3-(trifluoromethyl)phenyl]propyl})amine. This product is intended for research and analytical applications.
    Cinacalcet impurity 1 (Standard)
  • HY-106991AR
    Amustaline dihydrochloride (Standard)
    Amustaline (dihydrochloride) (Standard) is the analytical standard of Amustaline (dihydrochloride). This product is intended for research and analytical applications. Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products).
    Amustaline dihydrochloride (Standard)
  • HY-W017105R
    Pyrazine-2,3-dicarboxylic acid (Standard)
    Pyrazine-2,3-dicarboxylic acid (Standard) is the analytical standard of Pyrazine-2,3-dicarboxylic acid. This product is intended for research and analytical applications. Pyrazine-2,3-dicarboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Pyrazine-2,3-dicarboxylic acid (Standard)
  • HY-W011733R
    Tulobuterol hydrochloride (Standard)
    Tulobuterol (hydrochloride) (Standard) is the analytical standard of Tulobuterol (hydrochloride). This product is intended for research and analytical applications. Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation.
    Tulobuterol hydrochloride (Standard)
  • HY-A0031R
    Bazedoxifene (Standard)
    Bazedoxifene (Standard) is the analytical standard of Bazedoxifene. This product is intended for research and analytical applications. Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer.
    Bazedoxifene (Standard)