Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
-
Reference Standards Related Products (11754)
Related Products (11754)
-
Enitociclib (Standard)
0 ImagesCat. No.: HY-103019RCAS No.: 1610408-97-3Synonyms: (+)-BAY-1251152 (Standard); (+)-VIP152 (Standard); (S)-Enitociclib (Standard)Enitociclib (Standard) is the analytical standard of Enitociclib (HY-103019). This product is intended for research and analytical applications. Enitociclib ((+)-BAY-1251152; (+)-VIP152) is a selective CDK9 inhibitor (IC50=3 nM) that inhibits transcriptional elongation by blocking Ser2/Ser5 phosphorylation of RNA polymerase II. Enitociclib specifically depletes key short-lived proteins such as c-MYC, MCL-1 and induces tumor cell apoptosis. Enitociclib also interferes with the production of enhancer RNAs (eRNA) and enhancer-promoter interactions, and downregulates oncogene expression at the epigenetic level. Enitociclib exerts synergistic effects with agents including Bortezomib (HY-10227), Lenalidomide (HY-A0003), Pomalidomide (HY-10984), Venetoclax (HY-15531) and Paclitaxel (HY-B0015), and even reverses paclitaxel resistance. Enitociclib serves as a vital research tool for various malignancies such as double-hit diffuse large B-cell lymphoma, multiple myeloma and pancreatic ductal adenocarcinoma.
-
Ginsenoside Ro (Standard)
0 ImagesCat. No.: HY-N0607RCAS No.: 34367-04-9Synonyms: Polysciasaponin P3 (Standard); Chikusetsusaponin 5 (Standard); Chikusetsusaponin V (Standard)Ginsenoside Ro (Standard) is the analytical standard of Ginsenoside Ro. This product is intended for research and analytical applications. Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) exhibits a Ca2+-antagonistic antiplatelet effect with an IC50 of 155 μM. Ginsenoside Ro reduces the production of TXA2 more than it reduces the activities of COX-1 and TXAS.
-
1,3-Dicaffeoylquinic acid (Standard)
0 ImagesCat. No.: HY-N1412RCAS No.: 19870-46-3Synonyms: 1,3-O-Dicaffeoylquinic acid (Standard); 1,5-Dicaffeoylquinic acid (Standard)1,3-Dicaffeoylquinic acid (Standard) is the analytical standard of 1,3-Dicaffeoylquinic acid. This product is intended for research and analytical applications. 1,3-Dicaffeoylquinic acid is a caffeoylquinic acid derivative that exhibits antioxidant activity and radical scavenging activity.
-
Licofelone (Standard)
0 ImagesSynonyms: ML-3000 (Standard)Licofelone (Standard) is the analytical standard of Licofelone. This product is intended for research and analytical applications. Licofelone (ML-3000) is a dual COX/5-lipoxygenase (5-LOX) inhibitor (IC50=0.21/0.18 μM, respectively) for the treatment of osteoarthritis. Licofelone exerts anti-inflammatory and anti-proliferative effects. Licofelone induces apoptosis, and decreases the production of proinflammatory leukotrienes and prostaglandins.
-
Azemiglitazone (Standard)
0 ImagesCat. No.: HY-108022RCAS No.: 1133819-87-0Synonyms: MSDC-0602 (Standard)Azemiglitazone (Standard) is the analytical standard of Azemiglitazone (HY-108022). This product is intended for research and analytical applications. Azemiglitazone (MSDC-0602) is an orally active thiazolidinedione (TZD) -like molecule, which binds to PPARγ with low binding and activating affinity. Azemiglitazone inhibits mitochondrial pyruvate carrier (MPC), which inhibits Alzheimer’s disease and diminishes nonalcoholic steatohepatitis (NASH) caused liver injury.
-
2-(Benzo[d][1,3]dioxol-5-ylamino)ethanol hydrochloride (Standard)
![2-(Benzo[d][1,3]dioxol-5-ylamino)ethanol hydrochloride (Standard)](https://file.medchemexpress.com/product_pic/hy-w103079r.gif "Click to View 2-(Benzo[d][1,3]dioxol-5-ylamino)ethanol hydrochloride (Standard) Product Detail")
0 ImagesCat. No.: HY-W103079RCAS No.: 94158-14-2Synonyms: 4-(2-Hydroxyethyl)amino-1,2-methylenedioxybenzene hydrochloride (Standard)2-(Benzo[d][1,3]dioxol-5-ylamino)ethanol hydrochloride (Standard) is the analytical standard of 2-(Benzo[d][1,3]dioxol-5-ylamino)ethanol hydrochloride. This product is intended for research and analytical applications.
-
Amsacrine (Standard)
0 ImagesSynonyms: m-AMSA (Standard); acridinyl anisidide (Standard)Amsacrine (Standard) is the analytical standard of Amsacrine. This product is intended for research and analytical applications. Amsacrine (m-AMSA; acridinyl anisidide) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells.
-
Immepip dihydrobromide (Standard)
0 ImagesCat. No.: HY-101321ARCAS No.: 164391-47-3Immepip (dihydrobromide) (Standard) is the analytical standard of Immepip (dihydrobromide). This product is intended for research and analytical applications. Immepip dihydrobromide is a H3 agonist. Immepip dihydrobromide can reduce cortical histamine release. Immepip dihydrobromide can be used for the research of neurological diseases.
-
Cefaclor (Standard)
0 ImagesCefaclor (Standard) is the analytical standard of Cefaclor. This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections.
-
Diformylphloroglucinol (Standard)
0 ImagesCat. No.: HY-W130232RCAS No.: 4396-13-8Diformylphloroglucinol (Standard) is the analytical standard of Diformylphloroglucinol (HY-W130232). This product is intended for research and analytical applications. Diformylphloroglucinol is an acylphloroglucinol compound that can be used in the synthesis of Psiguadial B. Psiguadial B is a neuroprotective agent.
-
NRX-252114 (Standard)
0 ImagesCat. No.: HY-111836RCAS No.: 2763260-39-3NRX-252114 (Standard) is the analytical standard of NRX-252114 (HY-111836). This product is intended for research and analytical applications. NRX-252114 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-252114 enhances the binding of pSer33/S37A β-catenin peptide for β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 induces mutant β-catenin degradation.
-
Antifungal agent 1 (Standard)
0 ImagesCat. No.: HY-102025RCAS No.: 1265166-14-0Antifungal agent 1 (Standard) is the analytical standard of Antifungal agent 1 (HY-102025). This product is intended for research and analytical applications. Antifungal agent 1 is a potent antifungal agent.
-
Trimethylamine N-oxide (Standard)
0 ImagesTrimethylamine N-oxide (Standard) is the analytical standard of Trimethylamine N-oxide. This product is intended for research and analytical applications. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.
-
Avadomide (Standard)
0 ImagesSynonyms: CC 122 (Standard)Avadomide (Standard) is the analytical standard of Avadomide. This product is intended for research and analytical applications. Avadomide is an orally active cereblon modulator. Avadomide modulates cereblon E3 ligase activity, inhibits NF-κB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide exhibits potent antitumor and immunomodulatory activities.
-
Avatrombopag maleate (Standard)
0 ImagesSynonyms: AKR-501 maleate (Standard); E5501 maleate (Standard); YM477 maleate (Standard)Avatrombopag (maleate) (Standard) is the analytical standard of Avatrombopag (maleate). This product is intended for research and analytical applications. Avatrombopag maleate (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag maleate mimics the biological activities of TPO. Avatrombopag maleate increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag maleate is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A.
-
SN 6 (Standard)
0 ImagesCat. No.: HY-107658RCAS No.: 415697-08-4SN 6 (Standard) is the analytical standard of SN 6 (HY-107658). This product is intended for research and analytical applications. SN 6 is a selective Na+/Ca2+ exchanger (NCX) inhibitor, and inhibits 45Ca2+ uptake by NCX1, NCX2, and NCX3, with IC50s of 2.9, 16, and 8.6 μM, respectively.
-
GSK3145095 (Standard)
0 ImagesCat. No.: HY-111946RCAS No.: 1622849-43-7GSK3145095 (Standard) is the analytical standard of GSK3145095 (HY-111946). This product is intended for research and analytical applications. GSK3145095 is a RIP1 Kinase inhibitor with an IC50 of 6.3 nM .
-
Ibufenac (Standard)
0 ImagesSynonyms: Dytransin (Standard)Ibufenac (Dytransin) is an orally active nonsteroidal anti-inflammatory agent. Ibufenac exerts anti-inflammatory, analgesic and antipyretic effects. Ibufenac is being studied for the treatment of rheumatic diseases such as rheumatoid arthritis.
-
Prexasertib (Standard)
0 ImagesCat. No.: HY-18174RCAS No.: 1234015-52-1Synonyms: LY2606368 (Standard); ACR-368 (Standard)Prexasertib (Standard) is the analytical standard of Prexasertib (HY-18174). This product is intended for research and analytical applications. Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint Kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. Prexasertib inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity.
-
UCL 2077 (Standard)
0 ImagesCat. No.: HY-108592RCAS No.: 918311-87-2UCL 2077 (Standard) is the analytical standard of UCL 2077 (HY-108592). This product is intended for research and analytical applications. UCL 2077 is a selective slow-afterhyperpolarization (sAHP) channel blocker (IC50 = 500 nM in hippocampal neurons in culture), having minimal effects on Ca2+ channels, action potentials, input resistance and the medium after hyperpolarization. UCL 2077 is also a subtype-selective blocker of the epilepsy associated KCNQ channels.
